YLR315W 123.077521 INESSENTIAL biological_process unknown, molecular_function unknown, YDR457W 110.277681 INESSENTIAL TOM1 hect-domain-containing protein, containing kinase motifs; similar to Rsp5, polyubiquitylation*, ubiquitin--protein ligase, cellular_component unknown YBR272C 87.972941 INESSENTIAL HSM3 Hsm3p may be a member of the yeast MutS homolog family, mismatch repair, molecular_function unknown, YFR036W 79.619205 INESSENTIAL CDC26 cell division control protein, ubiquitin-dependent protein degradation*, ubiquitin--protein ligase*, anaphase-promoting complex YNL284C 78.190380 INESSENTIAL MRPL10 Mitochondrial ribosomal protein MRPL10 (YmL10), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YOR019W 40.499119 INESSENTIAL biological_process unknown, molecular_function unknown, YGL220W 30.494658 INESSENTIAL biological_process unknown, molecular_function unknown, YHR066W 30.449392 INESSENTIAL SSF1 homologous to Ssf2p,molecular_function unknown, YNL015W 30.064565 INESSENTIAL PBI2 Proteinase inhibitor that inhibits protease Prb1p (yscB), biological_process unknown, YHR048W 29.227105 INESSENTIAL biological_process unknown, YHR049C-A 28.094622 INESSENTIAL biological_process unknown, molecular_function unknown, YOR293W 26.773110 INESSENTIAL RPS10A Ribosomal protein S10A, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YLR046C 26.582539 INESSENTIAL biological_process unknown, molecular_function unknown, YNL166C 26.482155 IN BNI5 bud neck protein, biological_process unknown, molecular_function unknown, YHR034C 25.196959 INESSENTIAL biological_process unknown, molecular_function unknown, YGL023C 24.320181 INESSENTIAL PIB2 similar to Fab1 and Vps27; involved in telomere-proximal repression of gene expression,molecular_function unknown, YML095C-A 22.827955 INESSENTIAL biological_process unknown, molecular_function unknown, YHR046C 22.736038 INESSENTIAL Inositol monophosphatase, biological_process unknown, molecular_function unknown, YGL195W 22.175061 INESSENTIAL GCN1 translational activator of GCN4 through activation of GCN2 in response to starvation YAL048C 21.752444 INESSENTIAL molecular_function unknown YGL041C 21.409754 INESSENTIAL biological_process unknown, molecular_function unknown, YJR063W 21.223502 INESSENTIAL RPA12 A12.2 subunit of RNA polymerase I, transcription from Pol I promoter, DNA-directed RNA polymerase I, DNA-directed RNA polymerase I YPL091W 21.121151 INESSENTIAL GLR1 Glutathione oxidoreductase,glutathione reductase (NADPH), YGL206C 20.440625 INESSENTIAL CHC1 presumed vesicle coat protein YOR138C 20.073016 INESSENTIAL biological_process unknown, molecular_function unknown, YLR200W 19.766318 INESSENTIAL YKE2 Polypeptide 6 of a Yeast Non-native Actin Binding Complex, homolog of a component of the bovine NABC complex YHR078W 19.587056 INESSENTIAL biological_process unknown, molecular_function unknown, YLR049C 19.305672 INESSENTIAL biological_process unknown, molecular_function unknown, YGR231C 19.264475 INESSENTIAL PHB2 mitochondrial protein, prohibitin homolog; homolog of mammalian BAP37 and S. cerevisiae Phb1p, proteolysis and peptidolysis*, molecular_function unknown, mitochondrion YHR079C 18.790766 INESSENTIAL IRE1 Ire1p is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities, myo-inositol metabolism*, protein serine/threonine kinase*, endoplasmic reticulum membrane* YPL031C 18.561288 INESSENTIAL PHO85 cyclin-dependent protein kinase, protein phosphorylation*, cyclin-dependent protein kinase*, YFL023W 18.490920 INESSENTIAL FYV11 biological_process unknown, molecular_function unknown, cellular_component unknown YHR050W 18.403454 INESSENTIAL SMF2 localized to mitochondrial membrane, manganese ion transport, manganese ion transporter, mitochondrial membrane YMR304W 18.268145 INESSENTIAL UBP15 putative deubiquitinating enzyme, deubiquitylation, ubiquitin-specific protease, cellular_component unknown YOR227W 18.067566 INESSENTIAL biological_process unknown, molecular_function unknown, YNL223W 17.979887 INESSENTIAL AUT2 Anchor protein. Mediates attachment of autophagosomes to microtubules., autophagy*, microtubule binding, microtubule associated protein YBR038W 17.773527 IN CHS2 chitin synthase 2, cytokinesis*, chitin synthase, cytokinetic ring (sensu Saccharomyces) YIL110W 17.301151 INESSENTIAL biological_process unknown, molecular_function unknown, YGL200C 16.088872 INESSENTIAL EMP24 type I transmemebrane protein, component of COPII-coated, ER-derived transport vesicles YBR274W 15.662800 INESSENTIAL CHK1 Protein kinase Chk1, cell cycle, YHR091C 15.637681 INESSENTIAL MSR1 Arginyl-tRNA synthetase,arginine--tRNA ligase, YDR433W 15.508790 INESSENTIAL KRE22 biological_process unknown, molecular_function unknown, YDR092W 14.967403 INESSENTIAL UBC13 ubiquitin-conjugating enzyme, polyubiquitylation*, ubiquitin conjugating enzyme, nucleus YKL057C 14.200437 INESSENTIAL NUP120 100-kDa protein (predicted molecular weight is 120 kDa) with two leucine zipper motifs, coiled-coil region, and some homology to Nup133p, mRNA-nucleus export*, structural protein, nuclear pore YBL101C 14.188260 INESSENTIAL ECM21 involved in cell wall biogenesis,molecular_function unknown, YPL069C 14.115121 INESSENTIAL BTS1 geranylgeranyl diphosphate synthase YOR073W 13.987898 INESSENTIAL biological_process unknown, molecular_function unknown, YNL040W 13.948604 INESSENTIAL biological_process unknown, molecular_function unknown, YDL069C 13.921306 INESSENTIAL CBS1 translational activator of cytochrome b, protein biosynthesis, molecular_function unknown, mitochondrial inner membrane YHR080C 13.622224 INESSENTIAL biological_process unknown, molecular_function unknown, YDR422C 13.619392 INESSENTIAL SIP1 SNF1 protein kinase substrate, transcription, YNL029C 13.511752 INESSENTIAL KTR5 Putative mannosyltransferase, cell wall organization and biogenesis*, mannosyltransferase, Golgi apparatus YJL006C 13.483963 INESSENTIAL CTK2 cyclin-like protein, protein phosphorylation*, cyclin, YNL208W 13.301541 INESSENTIAL biological_process unknown, molecular_function unknown, YMR275C 13.207449 INESSENTIAL BUL1 Rsp5p ubiquitin ligase binding protein, polyubiquitylation*, molecular_function unknown, plasma membrane YDL216C 13.120201 INESSENTIAL RRI1 biological_process unknown, molecular_function unknown, cellular_component unknown YER077C 13.096220 INESSENTIAL biological_process unknown, molecular_function unknown, YGL125W 13.083928 INESSENTIAL MET13 putative methylenetetrahydrofolate reductase (mthfr), protein biosynthesis*, structural protein of ribosome*, mitochondrial large ribosomal-subunit* YOL086C 12.953110 INESSENTIAL ADH1 Alcohol dehydrogenase,acylglycerone-phosphate reductase, YOL049W 12.905269 INESSENTIAL GSH2 Glutathione Synthetase,glutathione synthase, YMR032W 12.807841 INESSENTIAL HOF1 SH3 domain containing-protein, cytokinesis, cytoskeletal protein binding protein, cytokinetic ring (sensu Saccharomyces) YMR256C 12.802004 INESSENTIAL COX7 subunit VII of cytochrome c oxidase,cytochrome-c oxidase, YAL016W 12.554597 INESSENTIAL TPD3 protein phosphatase 2A regulatory subunit A, protein biosynthesis*, protein phosphatase type 2A, protein phosphatase type 2A YKL113C 12.487821 INESSENTIAL RAD27 42 kDa 5' to 3' exonuclease required for Okazaki fragment processing, DNA repair, YDL090C 12.469516 INESSENTIAL RAM1 beta subunit of farnesyltransferase YLR441C 12.466400 INESSENTIAL RPS1A Ribosomal protein S1A (rp10A), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YPL024W 12.443297 INESSENTIAL NCE4 involved in cell separation YLR262C 12.428776 INESSENTIAL YPT6 highly homologous to the human GTPase, Rab6 YCR020W-B 12.395328 INESSENTIAL HTL1 high-temperature lethal, biological_process unknown, molecular_function unknown, YMR002W 12.384157 INESSENTIAL biological_process unknown, molecular_function unknown, YKL169C 12.353017 INESSENTIAL biological_process unknown, molecular_function unknown, YDL005C 12.245408 INESSENTIAL MED2 Stoichiometric member of mediator complex, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YDR027C 12.129748 INESSENTIAL LUV1 involved in vacuole biogenesis,molecular_function unknown, YER068W 12.098877 INESSENTIAL MOT2 putative zinc finger protein, mating (sensu Saccharomyces), YPR106W 12.020850 INESSENTIAL ISR1 protein kinase,protein kinase, YDR470C 11.983918 INESSENTIAL UGO1 mitochondrial fusion, molecular_function unknownmitochondrial outer membrane YLR333C 11.727855 INESSENTIAL RPS25B Ribosomal protein S25B (S31B) (rp45) (YS23), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDR340W 11.662299 INESSENTIAL biological_process unknown, molecular_function unknown, YNL234W 11.567291 INESSENTIAL biological_process unknown, molecular_function unknown, YNL246W 11.567213 INESSENTIAL biological_process unknown, molecular_function unknown, YPL271W 11.561064 INESSENTIAL ATP15 nuclear gene for ATP synthase epsilon subunit, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, central stalk YIL098C 11.547204 INESSENTIAL FMC1 Formation of Mitochondrial Cytochromes 1 YLR304C 11.339933 INESSENTIAL ACO1 Aconitase, mitochondrial, tricarboxylic acid cycle*, aconitate hydratase, cytosol* YNL021W 11.209242 INESSENTIAL HDA1 histone deacetylase, shares sequence similarity with Rpd3p, Hos1p, Hos2p, and Hos3p, chromatin architecture*, histone deacetylase, histone deacetylase complex YDR226W 11.182613 INESSENTIAL ADK1 adenylate kinase,adenylate kinase, YPL086C 11.114430 INESSENTIAL ELP3 RNA polymerase II-associated Histone acetyltransferase YBR166C 11.098116 INESSENTIAL TYR1 Prephenate dehydrogenase (NADP+),prephenate dehydrogenase (NADP+), YNL235C 10.996788 INESSENTIAL biological_process unknown, molecular_function unknown, YDL044C 10.954805 INESSENTIAL MTF2 involved in mRNA splicing, mRNA processing, RNA binding, mitochondrion YOL148C 10.812968 INESSENTIAL SPT20 transcription factor, member of the histone acetyltransferase SAGA complex SAGA complex YGL141W 10.798885 INESSENTIAL HUL5 ubiquitin-protein ligase (E3), polyubiquitylation*, ubiquitin--protein ligase, cellular_component unknown YDL042C 10.737489 INESSENTIAL SIR2 regulator of silencing at HML, HMR, telomeres, and rDNA, chromatin silencing at HML and HMR (sensu Saccharomyces)*, histone deacetylase, nucleolus* YGR181W 10.729536 INESSENTIAL TIM13 Subunit of mitochondrial protein import machinery, mitochondrial translocation, protein transporter, mitochondrial intermembrane space YMR166C 10.646805 INESSENTIAL biological_process unknown, molecular_function unknown, YFL011W 10.643912 INESSENTIAL HXT10 high-affinity hexose transporter, transport, YPL260W 10.488358 INESSENTIAL biological_process unknown, molecular_function unknown, YJL063C 10.484888 INESSENTIAL MRPL8 Mitochondrial ribosomal protein MRPL8 (YmL8) (E. coli L17), protein biosynthesis*, structural protein of ribosome, mitochondrial large ribosomal-subunit YDR418W 10.261203 INESSENTIAL RPL12B Ribosomal protein L12B (L15B) (YL23), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YNR010W 10.201337 INESSENTIAL CSE2 Component of RNA polymerase II mediator subcomplex, transcription from Pol II promoter*, RNA polymerase II transcription mediator, mediator complex YKR074W 10.171762 INESSENTIAL biological_process unknown, molecular_function unknown, YDR121W 10.146666 INESSENTIAL DPB4 DNA polymerase II (epsilon) 4th subunit, lagging strand elongation*, epsilon DNA polymerase, epsilon DNA polymerase YGL174W 10.105878 INESSENTIAL BUD13 biological_process unknown, molecular_function unknown, YLR261C 10.086672 INESSENTIAL biological_process unknown, molecular_function unknown, YNL008C 10.077884 INESSENTIAL biological_process unknown, molecular_function unknown, YNL005C 9.996925 INESSENTIAL MRP7 Mitochondrial ribosomal protein MRP7 (YmL2) (E. coli L27), protein biosynthesis, structural protein of ribosome*, mitochondrial large ribosomal-subunit YHR059W 9.906818 INESSENTIAL FYV4 biological_process unknown, molecular_function unknown, cellular_component unknown YIL128W 9.860412 INESSENTIAL MET18 regulator of TFIIH, transcription from Pol II promoter*, RNA polymerase II transcription factor, nucleoplasm YHR051W 9.847912 INESSENTIAL COX6 subunit VI of cytochrome c oxidase,cytochrome-c oxidase, YFL036W 9.794744 INESSENTIAL RPO41 mitohcondrial RNA polymerase, mitochondrial genome maintenance*, DNA-directed RNA polymerase, mitochondrial matrix YNL169C 9.752894 INESSENTIAL PSD1 Phosphatidylserine Decarboxylase 1,phosphatidylserine decarboxylase, YDR245W 9.725181 INESSENTIAL MNN10 galactosyltransferase, actin filament organization*, alpha-1,6-mannosyltransferase, mannosyltransferase complex YLR073C 9.714732 INESSENTIAL biological_process unknown, molecular_function unknown, YOR309C 9.678267 INESSENTIAL biological_process unknown, molecular_function unknown, YML056C 9.663336 INESSENTIAL IMD4 IMP dehydrogenase homolog, biological_process unknown, IMP dehydrogenase, cellular_component unknown YJR125C 9.624901 INESSENTIAL ENT3 Ent3p, actin filament organization*, cytoskeletal adaptor, actin cortical patch (sensu Saccharomyces) YDR089W 9.616769 INESSENTIAL biological_process unknown, molecular_function unknown, YJL077C 9.613400 INESSENTIAL ICS3 Increased Copper Sensitivity,molecular_function unknown, YPR077C 9.606382 INESSENTIAL biological_process unknown, molecular_function unknown, YJL075C 9.162497 INESSENTIAL biological_process unknown, molecular_function unknown, YLR139C 9.151645 INESSENTIAL SLS1 73 kDa mitochondrial integral membrane protein YIL095W 8.970796 INESSENTIAL PRK1 probable serine threonine-protein kinase, protein phosphorylation*, protein serine/threonine kinase, actin cortical patch (sensu Saccharomyces) YGR062C 8.970289 INESSENTIAL COX18 required for mitochondrial cytochrome oxidase activity, cytochrome c oxidase biogenesis, molecular_function unknown, mitochondrial membrane YJL003W 8.508919 INESSENTIAL biological_process unknown, molecular_function unknown, YOL008W 8.466311 INESSENTIAL biological_process unknown, molecular_function unknown, YGL170C 8.432330 INESSENTIAL SPO74 biological_process unknown, molecular_function unknown, YGR078C 8.422433 INESSENTIAL PAC10 Polypeptide 3 of a Yeast Non-native Actin Binding Complex, homolog of a component of the bovine NABC complex, tubulin folding, molecular_function unknown, cellular_component unknown YHR182W 8.333133 INESSENTIAL biological_process unknown, molecular_function unknown, YLL033W 8.316083 INESSENTIAL biological_process unknown, molecular_function unknown, YJL028W 8.313550 INESSENTIAL biological_process unknown, molecular_function unknown, YIL139C 8.305123 INESSENTIAL REV7 subunit of DNA polymerase-zeta (Pol-zeta), an enzyme whose sole function appears to be translesion synthesis, DNA repair*, zeta DNA polymerase, nucleus YMR066W 8.249474 INESSENTIAL SOV1 (putative) involved in respiration,molecular_function unknown, YPL084W 8.020468 INESSENTIAL BRO1 BCK1-like resistance to osmotic shock, signal transduction, molecular_function unknown, cellular_component unknown YJL102W 7.974398 INESSENTIAL MEF2 mitochondrial elongation factor G-like protein, protein synthesis elongation, translation elongation factor, mitochondrion YOL035C 7.839473 INESSENTIAL biological_process unknown, molecular_function unknown, YHR073W 7.768105 INESSENTIAL OSH3 Oxysterol-binding protein, biological_process unknown, molecular_function unknown, YGL208W 7.690436 INESSENTIAL SIP2 component of Snf1 protein complex involved in response to glucose starvation, transcription, YLR234W 7.680497 INESSENTIAL TOP3 DNA Topoisomerase III, meiotic recombination*, DNA topoisomerase I, YNR047W 7.638611 INESSENTIAL biological_process unknown, molecular_function unknown, YPL268W 7.573668 INESSENTIAL PLC1 phosphoinositide-specific phospholipase C, pseudohyphal growth*, 1-phosphatidylinositol-4,5-biphosphate phosphodiesterase, cellular_component unknown YKL002W 7.566175 INESSENTIAL DID4 biological_process unknown, molecular_function unknown, YKL150W 7.556981 INESSENTIAL MCR1 NADH-cytochrome b5 reductase,cytochrome b5 reductase, YGL072C 7.554705 INESSENTIAL biological_process unknown, molecular_function unknown, YDR241W 7.406134 INESSENTIAL BUD26 BUD site selection, biological_process unknown, molecular_function unknown, YFR049W 7.396937 INESSENTIAL YMR31 mitochondrial ribosomal protein (precursor), protein biosynthesis, structural protein of ribosome, mitochondrial small ribosomal-subunit YNL307C 7.382133 INESSENTIAL MCK1 43.1 kDa Serine threonine tyrosine protein kinase, protein phosphorylation*, protein threonine/tyrosine kinase, soluble fraction YNL064C 7.333829 INESSENTIAL YDJ1 yeast dnaJ homolog (nuclear envelope protein); heat shock protein YKR082W 7.311946 INESSENTIAL NUP133 nuclear pore protein, mRNA-nucleus export*, structural protein, nuclear pore YGR086C 7.238065 INESSENTIAL biological_process unknown, molecular_function unknown, YGL246C 7.226676 INESSENTIAL RAI1 biological_process unknown, molecular_function unknown, YKL009W 7.220278 INESSENTIAL MRT4 involved in mRNA decay,molecular_function unknown, YJR030C 7.217532 INESSENTIAL biological_process unknown, molecular_function unknown, YDR210W 7.188100 INESSENTIAL biological_process unknown, molecular_function unknown, YDR165W 7.120666 INESSENTIAL biological_process unknown, molecular_function unknown, YKR044W 7.085022 INESSENTIAL biological_process unknown, molecular_function unknown, YJL059W 6.974645 INESSENTIAL YHC3 Homolog of human CLN3, biological_process unknown, molecular_function unknown, YBR163W 6.942830 INESSENTIAL DEM1 Weak similarity to Pta1p (pre-tRNA processing protein), biological_process unknown, molecular_function unknown, cellular_component unknown YHR039C-B 6.938350 INESSENTIAL YNL037C 6.882135 INESSENTIAL IDH1 alpha-4-beta-4 subunit of mitochondrial isocitrate dehydrogenase 1, tricarboxylic acid cycle*, isocitrate dehydrogenase (NAD+), mitochondrial matrix YDR441C 6.840011 INESSENTIAL APT2 Adenine Phosphoribosyltransferase,adenine phosphoribosyltransferase, YDR138W 6.829518 INESSENTIAL HPR1 involved in mitosis, recombination; similar to TOP1 across 2 regions, DNA recombination, molecular_function unknown, nucleus YCR091W 6.816125 INESSENTIAL KIN82 Putative serine threonine protein kinase most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily, biological_process unknown, protein kinase, YGL143C 6.780507 INESSENTIAL MRF1 Mitochondrial polypeptide chain release factor, protein biosynthesis*, translation release factor, mitochondrion YIL149C 6.722992 INESSENTIAL MLP2 colied-coil protein (putative), similar to myosin and TPR, protein-nucleus import, molecular_function unknown, nuclear membrane* YGL009C 6.675415 INESSENTIAL LEU1 isopropylmalate isomerase,3-isopropylmalate dehydratase, YDL083C 6.651276 INESSENTIAL RPS16B Ribosomal protein S16B (rp61R), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YMR067C 6.610361 INESSENTIAL biological_process unknown, molecular_function unknown, YNL199C 6.569458 INESSENTIAL GCR2 Transcription factor, glycolysis, YPR099C 6.547756 INESSENTIAL biological_process unknown, molecular_function unknown, YGR262C 6.540907 INESSENTIAL BUD32 biological_process unknown, molecular_function unknown, cellular_component unknown YPR132W 6.536454 INESSENTIAL RPS23B Ribosomal protein S23B (S28B) (rp37) (YS14), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDL038C 6.491760 INESSENTIAL biological_process unknown, molecular_function unknown, YLR074C 6.455561 INESSENTIAL BUD20 BUD site selection, biological_process unknown, molecular_function unknown, cellular_component unknown YBL093C 6.343145 INESSENTIAL ROX3 RNA polymerase II holoenzyme mediator subunit, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YER095W 6.254941 INESSENTIAL RAD51 RecA homolog; Rad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsis (independently of ZIP1 and DMC1), and interacts with Rad52p and Rad55p; human Rad51p homolog interacts with Brca2 protein which has been implicated in causing breast cancer,recombinase, YIL060W 6.209017 INESSENTIAL biological_process unknown, molecular_function unknown, YOR080W 6.095922 INESSENTIAL DIA2 Digs Into Agar, invasive growth, molecular_function unknown, cellular_component unknown YDR268W 6.084825 INESSENTIAL MSW1 mitochondrial tryptophanyl-tRNA synthetase,tryptophan--tRNA ligase, YJR034W 6.036694 INESSENTIAL PET191 involved in cytochrome c oxidase assembly, cytochrome c oxidase biogenesis, molecular_function unknown, mitochondrial inner membrane YCR028C-A 5.942914 INESSENTIAL RIM1 Single-stranded zinc finger DNA-binding protein YDR519W 5.937096 INESSENTIAL FKB2 FKBP (FK506 binding protein) 13; peptidylprolyl cis-trans isomerase activity, biological_process unknown, peptidylprolyl isomerase, endoplasmic reticulum membrane YNR073C 5.898018 INESSENTIAL biological_process unknown, molecular_function unknown, YDL094C 5.890238 INESSENTIAL biological_process unknown, molecular_function unknown, YLR228C 5.870994 INESSENTIAL ECM22 involved in cell wall biogenesis (putative), biological_process unknown, molecular_function unknown, YJL096W 5.765065 INESSENTIAL MRPL49 mitochondrial ribosomal protein of the large subunit, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YKL139W 5.664076 INESSENTIAL CTK1 alpha subunit of the kinase which phosphorylates the RNA polymerase largest subunit CTD (carboxyl-terminal domain), protein phosphorylation*, protein kinase, YBR277C 5.641956 INESSENTIAL biological_process unknown, molecular_function unknown, YLR093C 5.576915 INESSENTIAL NYV1 vacuolar v-SNARE, non-selective vesicle fusion, v-SNARE, vacuolar membrane YLR062C 5.544160 INESSENTIAL BUD28 biological_process unknown, molecular_function unknown, cellular_component unknown YOR241W 5.525325 INESSENTIAL MET7 Folylpolyglutamate synthetase,folylpolyglutamate synthase, YDR532C 5.465063 INESSENTIAL KRE28 biological_process unknown, molecular_function unknown, YOL067C 5.452841 INESSENTIAL RTG1 Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus YLL006W 5.399272 INESSENTIAL MMM1 mitochondrial outer membrane protein, mitochondrion inheritance*, molecular_function unknown, mitochondrial outer membrane YOR201C 5.387214 INESSENTIAL PET56 Ribose methyltransferase for mitochondrial 21S rRNA, ribosomal large subunit assembly and maintenance, rRNA (guanine-N1-)-methyltransferase, mitochondrion YML016C 5.373096 INESSENTIAL PPZ1 serine-threonine phosphatase Z,protein serine/threonine phosphatase, YOR035C 5.352365 INESSENTIAL SHE4 Required for mother cell-specific HO expression,molecular_function unknown, YPL042C 5.319647 INESSENTIAL SSN3 a cyclin(SSN8)-dependent serine threonine protein kinase, protein phosphorylation*, non-specific RNA polymerase II transcription factor*, transcription factor complex YLR233C 5.318346 INESSENTIAL EST1 involved in telomere length regulation YMR266W 5.313176 INESSENTIAL RSN1 biological_process unknown, molecular_function unknown, YIL035C 5.295752 INESSENTIAL CKA1 alpha subunit of casein kinase II, establishment of cell polarity (sensu Saccharomyces)*, casein kinase II, casein kinase II YOR089C 5.274071 INESSENTIAL VPS21 small GTP-binding protein; geranylgeranylated; geranylgeranylation required for membrane association; also involved in endocytosis post vesicle internalization, endocytosis, YNL003C 5.206006 INESSENTIAL PET8 mitochondrial carrier protein family, biological_process unknown, molecular_function unknown, cellular_component unknown YML054C 5.188879 INESSENTIAL CYB2 Cytochrome b2 [L--lactate cytochrome-c oxidoreductase],L-lactate dehydrogenase (cytochrome), YJR079W 5.185898 INESSENTIAL biological_process unknown, molecular_function unknown, YNL164C 5.104045 INESSENTIAL biological_process unknown, molecular_function unknown, YLR251W 5.100169 INESSENTIAL biological_process unknown, molecular_function unknown, YNR022C 5.064984 INESSENTIAL biological_process unknown, molecular_function unknown, YER074W 5.057421 INESSENTIAL RPS24A 40S ribosomal protein S24A, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YPR101W 5.022389 INESSENTIAL SNT309 Component of a protein complex associated with the splicing factor Prp19p., mRNA splicing, YLR242C 5.019369 INESSENTIAL ARV1 similar to Nup120p and C.elegans R05H5.5 protein and Nup120p, biological_process unknown, molecular_function unknown, YDR025W 5.000218 INESSENTIAL RPS11A Ribosomal protein S11A (S18A) (rp41A) (YS12), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YPL045W 4.893511 INESSENTIAL VPS16 Vacuolar sorting protein, protein-vacuolar targeting*, molecular_function unknown, vacuolar membrane* YDR452W 4.883698 INESSENTIAL PHM5 vacuolar polyphosphatase YHR183W 4.855999 INESSENTIAL GND1 Phosphogluconate Dehydrogenase (Decarboxylating),phosphogluconate dehydrogenase (decarboxylating), YGL087C 4.763762 INESSENTIAL MMS2 Similar to ubiquitin conjugating protein family, ubiquitin-dependent protein degradation*, ubiquitin conjugating enzyme, cellular_component unknown YBR189W 4.761086 INESSENTIAL RPS9B Ribosomal protein S9B (S13) (rp21) (YS11), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YFR019W 4.727882 INESSENTIAL FAB1 type II PI(4)P5-kinase (PIP4,5 kinase) similar to human PIP5K-II, vacuole organization and biogenesis, 1-phosphatidylinositol-3-phosphate 5-kinase, vacuolar membrane YGL229C 4.721713 INESSENTIAL SAP4 Sit4 protein phosphatase-associated protein, G1/S transition of mitotic cell cycle, protein serine/threonine phosphatase, cytoplasm YDR315C 4.675221 INESSENTIAL IPK1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IP5 2-kinase) YPL029W 4.672830 INESSENTIAL SUV3 putative ATP-dependent helicase,RNA helicase, YNL011C 4.537965 INESSENTIAL biological_process unknown, molecular_function unknown, YNL028W 4.529307 INESSENTIAL biological_process unknown, molecular_function unknown, YOR209C 4.493421 INESSENTIAL NPT1 nicotinate phosphoribosyl transferase (putative),nicotinate phosphoribosyltransferase, YML128C 4.389130 INESSENTIAL MSC1 biological_process unknown, molecular_function unknown, cellular_component unknown YPL274W 4.371586 INESSENTIAL SAM3 High affinity S-adenosylMethionine Permease, sulfur amino acid transport, amino acid-polyamine transporter, cellular_component unknown YBR200W 4.364414 INESSENTIAL BEM1 contains two SH3 domains YKL166C 4.352877 INESSENTIAL TPK3 cAMP-dependent protein kinase catalytic subunit, protein phosphorylation*, protein serine/threonine kinase*, cytoplasm* YLR270W 4.330152 INESSENTIAL biological_process unknown, molecular_function unknown, YNL139C 4.307399 INESSENTIAL RLR1 Involved in transcription, transcription,nucleus YHR064C 4.245845 INESSENTIAL PDR13 Hsp70 Protein YOL033W 4.221712 INESSENTIAL MSE1 Mitochondrial glutamyl-tRNA synthetase,glutamate--tRNA ligase, YOR312C 4.214524 INESSENTIAL RPL20B 60S ribosomal protein L20B (L18B), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YNL187W 4.210719 INESSENTIAL biological_process unknown, molecular_function unknown, YHR167W 4.203272 INESSENTIAL THP2 biological_process unknown, molecular_function unknown, nucleus YML014W 4.185904 INESSENTIAL biological_process unknown, molecular_function unknown, YHR168W 4.185755 INESSENTIAL GTP-binding protein, biological_process unknown, molecular_function unknown, YML115C 4.183873 INESSENTIAL VAN1 mannosyltransferase,mannosyltransferase, YKR054C 4.139571 INESSENTIAL DYN1 heavy chain of cytoplasmic dynein, mitotic chromosome segregation*, motor, spindle pole body* YHR008C 4.132380 INESSENTIAL SOD2 Manganese-containing superoxide dismutase,superoxide dismutase, YJL189W 4.109209 INESSENTIAL RPL39 Ribosomal protein L39 (L46) (YL40), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YDR322W 4.094919 INESSENTIAL MRPL35 Mitochondrial ribosomal protein MRPL35 (YmL35), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YJR010C-A 4.087321 INESSENTIAL SPC1 signal peptidase subunit, signal peptide processing, molecular_function unknown, signal peptidase complex YGR234W 4.059291 INESSENTIAL YHB1 Flavohemoglobin, stress response, molecular_function unknown, cellular_component unknown YJL150W 4.024917 INESSENTIAL biological_process unknown, molecular_function unknown, YEL040W 4.019339 INESSENTIAL UTR2 biological_process unknown, molecular_function unknown, YGR036C 3.964147 INESSENTIAL CAX4 CAX4p contains 3 short stretches of amino acids that are characteristic for a wide variety of phosphatases, including lipid phosphatases and a protein phosphatase.,molecular_function unknown, YGL236C 3.958807 INESSENTIAL MTO1 Mitochondrial Translation Optimization; Strong similarity to E. coli GidA, protein biosynthesis, molecular_function unknown, mitochondrion YBL100C 3.957771 INESSENTIAL biological_process unknown, molecular_function unknown, YGL179C 3.954274 INESSENTIAL TOS3 biological_process unknown, YKL116C 3.949592 INESSENTIAL PRR1 probable serine threonine-specific protein kinase (EC 2.7.1.-), biological_process unknown, YPL149W 3.948661 INESSENTIAL APG5 involved in autophagy, autophagy*, molecular_function unknown, cellular_component unknown YLR382C 3.909733 INESSENTIAL NAM2 mitochondrial leucyl tRNA synthetase,leucine--tRNA ligase, YEL050C 3.898734 INESSENTIAL RML2 mitochondrial ribosomal protein L2 of the large subunit, protein biosynthesis*, structural protein of ribosome, mitochondrial large ribosomal-subunit YLR281C 3.861666 INESSENTIAL biological_process unknown, molecular_function unknown, YMR091C 3.823423 INESSENTIAL NPL6 involved in nuclear protein targeting,molecular_function unknown, YDL068W 3.784387 INESSENTIAL biological_process unknown, molecular_function unknown, YPL129W 3.771423 INESSENTIAL ANC1 transcription initiation factor TFIIF small subunit, transcription initiation from Pol II promoter*, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex* YBL059W 3.749577 INESSENTIAL biological_process unknown, molecular_function unknown, YGL101W 3.730349 INESSENTIAL biological_process unknown, molecular_function unknown, YLR306W 3.722439 INESSENTIAL UBC12 Ubiquitin-conjugating enzyme, polyubiquitylation*, ubiquitin conjugating enzyme, cellular_component unknown YAL046C 3.715321 INESSENTIAL biological_process unknown, molecular_function unknown, YBL058W 3.708474 INESSENTIAL SHP1 putative regulatory subunit for Glc7p, a phosphatase required for glucose repression, sporulation (sensu Saccharomyces)*, molecular_function unknown, cellular_component unknown YDR509W 3.705379 INESSENTIAL biological_process unknown, molecular_function unknown, YDL075W 3.692244 INESSENTIAL RPL31A Ribosomal protein L31A (L34A) (YL28), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YLR226W 3.668502 INESSENTIAL BUR2 involved in transcriptional regulation, mitotic chromosome segregation, molecular_function unknown, cellular_component unknown YLR096W 3.651184 INESSENTIAL KIN2 Serine threonine protein kinase YBR251W 3.627055 INESSENTIAL MRPS5 Probable mitochondrial ribosomal protein S5, protein biosynthesis, structural protein of ribosome, mitochondrial ribosome YGL173C 3.623778 INESSENTIAL KEM1 cytoplasmic 5'-to-3' exonuclease., 35S primary transcript processing*, 5'-3' exoribonuclease, cytoplasm YBL047C 3.609334 INESSENTIAL EDE1 USO1 homolog (S. cerevisiae), cytoskeletal-related transport protein, Ca++ binding, biological_process unknown*, molecular_function unknown, actin cortical patch (sensu Saccharomyces) YER004W 3.607049 INESSENTIAL biological_process unknown, molecular_function unknown, YCR083W 3.597872 INESSENTIAL TRX3 mitochondrial thioredoxin, oxidative stress response, thioredoxin, mitochondrion YLR264W 3.593775 INESSENTIAL RPS28B Ribosomal protein S28B (S33B) (YS27), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YMR250W 3.534555 INESSENTIAL GAD1 glutamate decarboxylase, amino acid metabolism, glutamate decarboxylase, cellular_component unknown YNL030W 3.524138 INESSENTIAL HHF2 Histone H4 (HHF1 and HHF2 code for identical proteins) YPL262W 3.480199 INESSENTIAL FUM1 mitochondrial and cytoplasmic fumarase (fumarate hydralase), tricarboxylic acid cycle*, fumarate hydratase, cytosol* YOR034C 3.473484 INESSENTIAL AKR2 involved in constitutive endocytosis of Ste3p,molecular_function unknown, YJL088W 3.443329 INESSENTIAL ARG3 Ornithine carbamoyltransferase, arginine biosynthesis*, ornithine carbamoyltransferase, cytosol YIL009C-A 3.438243 INESSENTIAL EST3 181aa protein - 20.5 kD,molecular_function unknown, YDL047W 3.428689 INESSENTIAL SIT4 type 2A related protein phosphatase, G1/S transition of mitotic cell cycle, protein serine/threonine phosphatase, cytoplasm YLR318W 3.425571 INESSENTIAL EST2 103 kD basic protein, catalytic subunit of telomerase YNL192W 3.423848 INESSENTIAL CHS1 chitin synthase 1, cytokinesis, chitin synthase, YOR383C 3.416684 INESSENTIAL FIT3 biological_process unknown, molecular_function unknown, YLR043C 3.416445 INESSENTIAL TRX1 thioredoxin, oxidative stress response*, thioredoxin, cytosol YJL092W 3.410858 INESSENTIAL HPR5 DNA helicase, DNA repair, DNA helicase, nucleus YGR096W 3.410394 INESSENTIAL biological_process unknown, molecular_function unknown, YPL193W 3.376813 INESSENTIAL RSA1 RiboSome Assembly, ribosomal large subunit assembly and maintenance, molecular_function unknown, nucleoplasm YBR162C 3.352971 INESSENTIAL TOS1 YNL236W 3.350291 INESSENTIAL SIN4 component of RNA polymerase II holoenzyme mediator complex, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YOL095C 3.345748 INESSENTIAL HMI1 mitochondrial DNA helicase (putative), biological_process unknown, YGL033W 3.335285 INESSENTIAL HOP2 Meiosis-specific gene required for the pairing of homologous chromosomes,molecular_function unknown, YKL096W 3.332013 INESSENTIAL CWP1 cell wall mannoprotein YGL003C 3.319264 INESSENTIAL CDH1 protein required for Clb2 and Ase1 degradation, ubiquitin-dependent protein degradation*, enzyme activator, anaphase-promoting complex YIL133C 3.301436 INESSENTIAL RPL16A Ribosomal protein L16A (L21A) (rp22) (YL15), protein biosynthesis, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YLL013C 3.271604 INESSENTIAL biological_process unknown, molecular_function unknown, YDR105C 3.260932 INESSENTIAL biological_process unknown, molecular_function unknown, YGL015C 3.201931 INESSENTIAL biological_process unknown, molecular_function unknown, YGR104C 3.169110 INESSENTIAL SRB5 subunit of RNA polymerase II holoenzyme mediator complex, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YOL076W 3.158515 INESSENTIAL MDM20 involved in mitochondrial inheritance and actin assembly, cytoskeleton organization and biogenesis*, actin binding, intracellular YIL134W 3.146673 INESSENTIAL FLX1 mitochondrial inner membrane carrier protein for FAD, mitochondrial transport, flavin adenine dinucleotide transporter, mitochondrion YPR163C 3.137828 INESSENTIAL TIF3 Translation initiation factor eIF-4B, protein synthesis initiation, translation initiation factor, ribosome YPR036W 3.121367 INESSENTIAL VMA13 vacuolar ATPase V1 domain subunit H (54 kDa), vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V1 domain YNL302C 3.118442 INESSENTIAL RPS19B Ribosomal protein S19B (rp55B) (S16aB) (YS16B), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDR442W 3.081892 INESSENTIAL biological_process unknown, molecular_function unknown, YFL001W 3.079749 INESSENTIAL DEG1 Depressed growth-rate protein, RNA processing, pseudouridylate synthase, nucleus* YJR113C 3.075455 INESSENTIAL RSM7 protein of the small subunit of the mitochondrial ribosome YFL016C 3.062357 INESSENTIAL MDJ1 DnaJ homolog involved in mitochondrial biogenesis and protein folding, protein folding*, heat shock protein, mitochondrial inner membrane YJR131W 3.050168 INESSENTIAL MNS1 specific alpha-mannosidase,mannosyl-oligosaccharide 1,2-alpha-mannosidase, YIL028W 3.014903 INESSENTIAL biological_process unknown, molecular_function unknown, YDR520C 3.005181 INESSENTIAL biological_process unknown, molecular_function unknown, YNL133C 3.004951 INESSENTIAL FYV6 biological_process unknown, molecular_function unknown, cellular_component unknown YFR001W 2.950219 INESSENTIAL LOC1 Double-stranded RNA-binding protein YER070W 2.925901 INESSENTIAL RNR1 ribonucleotide reductase, DNA replication, ribonucleoside-diphosphate reductase, cytosol YPR114W 2.893096 INESSENTIAL biological_process unknown, molecular_function unknown, YHR057C 2.889159 INESSENTIAL CYP2 Peptidylprolyl isomerase (cyclophilin) ER or secreted, stress response, peptidylprolyl isomerase, cellular_component unknown YGL219C 2.885250 INESSENTIAL biological_process unknown, molecular_function unknown, cellular_component unknown YGL211W 2.870812 INESSENTIAL biological_process unknown, molecular_function unknown, YLR028C 2.839488 INESSENTIAL ADE16 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase IMP cyclohydrolase,IMP cyclohydrolase, YCR047C 2.822829 INESSENTIAL BUD23 Protein carboxyl methylase, biological_process unknown, molecular_function unknown, YGR217W 2.802023 INESSENTIAL CCH1 putative calcium channel, transport, YJL056C 2.795749 INESSENTIAL ZAP1 Metalloregulatory protein involved in zinc-responsive transcriptional regulation, transcription regulation from Pol II promoter*, specific RNA polymerase II transcription factor, YPR069C 2.777530 INESSENTIAL SPE3 putrescine aminopropyltransferase (spermidine synthase),spermidine synthase, YPL047W 2.753328 INESSENTIAL biological_process unknown, molecular_function unknown, YLR447C 2.724939 INESSENTIAL VMA6 vacuolar ATPase V0 domain subunit d (36 kDa), vacuolar acidification*, hydrogen-transporting two-sector ATPase, vacuolar membrane* YGR200C 2.695614 INESSENTIAL ELP2 90 kD subunit of elongator and elongating RNA pol II holoenzyme, transcription, YHR194W 2.686444 INESSENTIAL biological_process unknown, molecular_function unknown, YCR073W-A 2.673269 INESSENTIAL SOL2 shows similarity to glucose-6-phosphate dehydrogenase non-catalytic domains; homologous to Sol1p and Sol3p,molecular_function unknown, YCL002C 2.622267 INESSENTIAL biological_process unknown, molecular_function unknown, YLR235C 2.615524 INESSENTIAL biological_process unknown, molecular_function unknown, YLR327C 2.605649 INESSENTIAL biological_process unknown, molecular_function unknown, YPL187W 2.559948 INESSENTIAL MF mating factor alpha, pheromone response, pheromone, extracellular YDR155C 2.537694 INESSENTIAL CPH1 cyclophilin peptidyl-prolyl cis-trans isomerase, biological_process unknown, peptidylprolyl isomerase, cytoplasm YKR001C 2.535610 INESSENTIAL VPS1 putative GTP-binding protein; similar to mammalian Mx proteins, protein-vacuolar targeting*, GTPase, membrane fraction YDR508C 2.493140 INESSENTIAL GNP1 high-affinity glutamine permease, transport, YER139C 2.473541 INESSENTIAL biological_process unknown, molecular_function unknown, YCR102C 2.433448 INESSENTIAL Alcohol dehydrogenase, biological_process unknown, molecular_function unknown, YHR047C 2.411825 INESSENTIAL AAP1 arginine alanine aminopeptidase, biological_process unknown, aminopeptidase, cellular_component unknown YGR180C 2.407386 INESSENTIAL RNR4 Ribonucleotide Reductase, DNA replication, ribonucleoside-diphosphate reductase, nucleus YDR443C 2.374822 INESSENTIAL SSN2 transcription factor, repression of transcription from Pol II promoter, non-specific RNA polymerase II transcription factor, transcription factor complex YJR032W 2.340834 INESSENTIAL CPR7 peptidyl-prolyl cis trans isomerase, biological_process unknown, peptidylprolyl isomerase, cytoplasm YGR257C 2.314853 INESSENTIAL biological_process unknown, molecular_function unknown, YJL183W 2.313118 INESSENTIAL MNN11 mannosyltransferase complex component, biological_process unknown, YMR089C 2.307891 INESSENTIAL YTA12 mitochondrial membrane ATPase of the CDC48 PAS1 SEC18 (AAA) family, protein complex assembly*, adenosinetriphosphatase*, mitochondrial inner membrane YLR372W 2.300792 INESSENTIAL SUR4 involved in fatty acid biosynthesis, fatty acid biosynthesis*, molecular_function unknown, endoplasmic reticulum membrane YFR030W 2.298873 INESSENTIAL MET10 subunit of assimilatory sulfite reductase, sulfate assimilation, sulfite reductase (NADPH), cellular_component unknown YDR296W 2.298741 INESSENTIAL MHR1 Involved in mitochondrial homologous DNA recombination,molecular_function unknown, YLR244C 2.264524 INESSENTIAL MAP1 methionine aminopeptidase,methionyl aminopeptidase, YHR038W 2.256259 INESSENTIAL FIL1 Putative mitochondrial ribosome recycling factor, protein biosynthesis, translation termination factor, mitochondrion YDL045W-A 2.254491 INESSENTIAL MRP10 homologous to Yml37p, component of the 37 S subunit of mitochondrial ribosomes, protein biosynthesis, structural protein of ribosome, mitochondrial small ribosomal-subunit YCL034W 2.252801 INESSENTIAL biological_process unknown, molecular_function unknown, YAL047C 2.247818 INESSENTIAL SPC72 component of spindle pole bodies, microtubule nucleation*, structural protein of cytoskeleton, outer plaque of spindle pole body YMR060C 2.233494 INESSENTIAL TOM37 mitochondrial import receptor, heterodimerizes with Tom70p, preferentially recognizes the mature regions of precursor proteins associated with ATP-dependent cytosolic chaperones, mitochondrial translocation, protein transporter, mitochondrial outer membrane translocase complex YOR096W 2.233299 INESSENTIAL RPS7A Ribosomal protein S7A (rp30), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YBR014C 2.232871 INESSENTIAL Glutaredoxin homolog, biological_process unknown, molecular_function unknown, YOL013W-A 2.227692 INESSENTIAL biological_process unknown, molecular_function unknown, YLR342W 2.104038 INESSENTIAL FKS1 1,3-beta-D-glucan synthase, cell wall organization and biogenesis*, 1,3-beta-glucan synthase, actin cap (sensu Saccharomyces)* YLL007C 2.064591 INESSENTIAL biological_process unknown, molecular_function unknown, YBL054W 2.054998 INESSENTIAL Homolog to myb transforming proteins, biological_process unknown, molecular_function unknown, YOR112W 2.046913 INESSENTIAL biological_process unknown, molecular_function unknown, YGR177C 2.031782 INESSENTIAL ATF2 Alcohol acetyltransferase,alcohol O-acetyltransferase, YCL036W 2.009723 INESSENTIAL biological_process unknown, molecular_function unknown, YDR337W 1.994164 INESSENTIAL MRPS28 Mitochondrial ribosomal protein MRPS28 (E. coli S15), protein biosynthesis*, structural protein of ribosome*, mitochondrial small ribosomal-subunit YLR118C 1.978305 INESSENTIAL biological_process unknown, molecular_function unknown, YOL109W 1.948729 INESSENTIAL ZEO1 Overexpression causes resistance to Zeocin,molecular_function unknown, YMR177W 1.938504 INESSENTIAL MMT1 (putative) mitochondrial metal transporter YMR162C 1.934436 INESSENTIAL biological_process unknown, molecular_function unknown, YGL135W 1.929596 INESSENTIAL RPL1B Ribosomal protein L1B, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YHR010W 1.910990 INESSENTIAL RPL27A Ribosomal protein L27A, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YLR295C 1.883141 INESSENTIAL ATP14 ATP synthase subunit h, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, F0 sector YGL108C 1.877325 INESSENTIAL biological_process unknown, molecular_function unknown, YKR018C 1.871792 INESSENTIAL biological_process unknown, molecular_function unknown, YML017W 1.860793 INESSENTIAL PSP2 (putative) involved in mRNA splicing,molecular_function unknown, YLR237W 1.847309 INESSENTIAL THI7 thiamine transporter, thiamin transport, thiamin transporter, plasma membrane YKR050W 1.811485 INESSENTIAL TRK2 membrane protein; low affinity potassium transport, transport, YGR159C 1.810706 INESSENTIAL NSR1 nuclear localization sequence binding protein, rRNA processing*, RNA binding, nucleolus YER154W 1.805748 INESSENTIAL OXA1 involved in cytochrome c oxidase and ATP synthase assembly, mitochondrial translocation, protein transporter, mitochondrial inner membrane YOR049C 1.792478 INESSENTIAL biological_process unknown, molecular_function unknown, YOR292C 1.759201 INESSENTIAL biological_process unknown, molecular_function unknown, YGR160W 1.757123 INESSENTIAL FYV13 biological_process unknown, molecular_function unknown, cellular_component unknown YIL077C 1.751481 INESSENTIAL biological_process unknown, molecular_function unknown, YJL176C 1.744407 INESSENTIAL SWI3 transcription factor, chromatin modeling, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex YEL006W 1.731192 INESSENTIAL biological_process unknown, molecular_function unknown, YGR215W 1.727117 INESSENTIAL RSM27 protein of the small subunit of the mitochondrial ribosome YPR067W 1.713350 INESSENTIAL ISA2 Iron Sulfur Assembly -- IscA NifA homolog, iron transport, molecular_function unknown, mitochondrial intermembrane space YNL177C 1.687085 INESSENTIAL biological_process unknown, molecular_function unknown, YGL016W 1.686254 INESSENTIAL KAP122 karyopherin-beta family protein YBL081W 1.673755 INESSENTIAL biological_process unknown, molecular_function unknown, YBR057C 1.668258 INESSENTIAL MUM2 similar to ubiquitin C-terminal hydrolase, involved in meiosis, meiosis, molecular_function unknown, YPR072W 1.666236 INESSENTIAL NOT5 member of the NOT complex, a global negative regulator of transcription, transcription, YDL198C 1.636820 INESSENTIAL YHM1 (putative) mitochondrial carrier protein, transport, YHR076W 1.630631 INESSENTIAL biological_process unknown, molecular_function unknown, YLR439W 1.604282 INESSENTIAL MRPL4 Mitochondrial 60S ribosomal protein L4, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YPR131C 1.601848 INESSENTIAL NAT3 N-terminal acetyltransferase YLR149C 1.597627 INESSENTIAL biological_process unknown, molecular_function unknown, YML018C 1.577200 INESSENTIAL biological_process unknown, molecular_function unknown, YDR300C 1.576477 INESSENTIAL PRO1 gamma-glutamyl kinase,glutamate 5-kinase, YNL165W 1.518890 INESSENTIAL biological_process unknown, molecular_function unknown, YML110C 1.511863 INESSENTIAL COQ5 Putative mitochondrial C-methyltransferase, ubiquinone metabolism,mitochondrion YPL188W 1.470096 INESSENTIAL POS5 involved in oxidative stress, biological_process unknown, molecular_function unknown, YLR386W 1.465091 INESSENTIAL biological_process unknown, molecular_function unknown, YDR450W 1.443902 INESSENTIAL RPS18A Ribosomal protein S18A, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDR363W-A 1.442894 INESSENTIAL SEM1 unknown function, similar to S. pombe Dss1,molecular_function unknown, YHR143W 1.440883 INESSENTIAL Ser-Thr rich protein, biological_process unknown, molecular_function unknown, YLR039C 1.439586 INESSENTIAL RIC1 involved in transcription of ribosomal protein genes and ribosomal RNA, transcription regulation from Pol II promoter*, molecular_function unknown, nucleus YPR148C 1.434860 INESSENTIAL biological_process unknown, molecular_function unknown, YGR165W 1.420963 INESSENTIAL biological_process unknown, molecular_function unknown, YGL129C 1.416584 INESSENTIAL RSM23 protein of the small subunit of the mitochondrial ribosome YGR154C 1.393326 INESSENTIAL biological_process unknown, molecular_function unknown, YGL036W 1.371502 INESSENTIAL MTC2 Mtf1 Two Hybrid Clone 2, biological_process unknown, molecular_function unknown, YDR417C 1.365887 INESSENTIAL biological_process unknown, molecular_function unknown, YNL081C 1.357721 INESSENTIAL biological_process unknown, molecular_function unknown, YNL135C 1.345186 INESSENTIAL FPR1 peptidylprolyl cis-trans isomerase, biological_process unknown, peptidylprolyl isomerase, cytoplasm YGR105W 1.319810 INESSENTIAL VMA21 vacuolar H+-ATPase assembly protein, vacuolar acidification, YLR067C 1.316071 INESSENTIAL PET309 involved in COX1 mRNA stability, protein biosynthesis*, molecular_function unknown, mitochondrial inner membrane YDR522C 1.282191 INESSENTIAL SPS2 involved in meiosis, meiosis, molecular_function unknown, YOR231W 1.277757 INESSENTIAL MKK1 protein kinase involved in protein kinase C pathway, protein phosphorylation*, MAP kinase kinase, cellular_component unknown YJL136C 1.275670 INESSENTIAL RPS21B Ribosomal protein S21B (S26B) (YS25), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YEL044W 1.275269 INESSENTIAL biological_process unknown, molecular_function unknown, YDL033C 1.236329 INESSENTIAL YLR403W 1.219503 INESSENTIAL SFP1 split zinc finger protein, biological_process unknown, YLR402W 1.206247 INESSENTIAL biological_process unknown, molecular_function unknown, YJL184W 1.158740 INESSENTIAL biological_process unknown, molecular_function unknown, YEL033W 1.146897 INESSENTIAL biological_process unknown, molecular_function unknown, YDR017C 1.146791 INESSENTIAL KCS1 Shows homology to basic leucine zipper family of transcription factors YNL055C 1.144705 INESSENTIAL POR1 Outer mitochondrial membrane porin (voltage-dependent anion channel, or VDAC), transport, YOR235W 1.110009 INESSENTIAL biological_process unknown, molecular_function unknown, YJL122W 1.095813 INESSENTIAL biological_process unknown, molecular_function unknown, YER054C 1.079622 INESSENTIAL GIP2 (putative) regulator of Glc7, a PP1 family protein phosphatase YHR093W 1.055553 INESSENTIAL AHT1 the AHT1 DNA sequence is upstream of HXT4 and contains an HXT4 regulatory element which is a multicopy suppressor of glucose transport defects; probable non-functional ORF, biological_process unknown, molecular_function unknown, YDR507C 1.015751 INESSENTIAL GIN4 putative serine threonine kinase, protein phosphorylation*, protein kinase, bud neck YGL118C 1.013191 INESSENTIAL biological_process unknown, molecular_function unknown, YCR046C 1.003082 INESSENTIAL IMG1 mitochondrial ribosomal protein, protein biosynthesis, structural protein of ribosome, mitochondrial ribosome YNL250W 0.995337 INESSENTIAL RAD50 Contains a purine-binding domain, two heptad repeats and a hydrophobic tail., DNA repair, YIL041W 0.983310 INESSENTIAL biological_process unknown, molecular_function unknown, YNL023C 0.971894 INESSENTIAL FAP1 Transcription factor homolog; similarity to Drosophila melanogaster shuttle craft protein; similarity to human NFX1 protein; similarity to human DNA-binding protein tenascin YMR026C 0.959309 INESSENTIAL PEX12 C3HC4 zinc-binding integral peroxisomal membrane protein, peroxisome organization and biogenesis, molecular_function unknown, peroxisomal membrane YER052C 0.958525 INESSENTIAL HOM3 Aspartate kinase (L-aspartate 4-P-transferase) (EC 2.7.2.4),aspartate kinase, YLR131C 0.958459 INESSENTIAL ACE2 zinc finger transcription factor, G1-specific transcription in mitotic cell cycle, transcription activating factor, nucleus* YKL119C 0.946680 INESSENTIAL VPH2 25.2 kDa protein involved in assembly of vacuolar H(+) ATPase, vacuolar acidification*, molecular_function unknown, endoplasmic reticulum membrane YGL240W 0.930734 INESSENTIAL DOC1 component of the anaphase-promoting complex, ubiquitin-dependent protein degradation*, enzyme activator, anaphase-promoting complex YGR225W 0.928331 INESSENTIAL AMA1 Required for sporulation; highly induced during sporulation YBL075C 0.928259 INESSENTIAL SSA3 heat-inducible cytosolic member of the 70 kDa heat shock protein family, stress response*, heat shock protein, cytoplasm YGR167W 0.925863 INESSENTIAL CLC1 Clathrin light chain YHR092C 0.915199 INESSENTIAL HXT4 High-affinity glucose transporter, transport, YMR267W 0.903354 INESSENTIAL PPA2 mitochondrial inorganic pyrophosphatase, respiration, inorganic diphosphatase, mitochondrion YGR153W 0.898989 INESSENTIAL TOS10 biological_process unknown, molecular_function unknown, YDR147W 0.858442 INESSENTIAL EKI1 Ethanolamine Kinase, phospholipid metabolism, ethanolamine kinase, YDL035C 0.855210 INESSENTIAL GPR1 G-protein coupled receptor YMR158W 0.843085 INESSENTIAL biological_process unknown, molecular_function unknown, YDR161W 0.827317 INESSENTIAL TCI1 interacts with PP2C, biological_process unknown, YLR240W 0.814223 INESSENTIAL VPS34 phosphatidylinositol 3-kinase, protein phosphorylation*, protein kinase*, membrane fraction YCL074W 0.785279 INESSENTIAL Reverse transcriptase YNL167C 0.778718 INESSENTIAL SKO1 CREB like repressor, bZIP protein that binds to CRE motifs, interacts with Mig1p, transcription, YLR338W 0.778140 INESSENTIAL KRE21 biological_process unknown, molecular_function unknown, YNL059C 0.772282 INESSENTIAL ARP5 Actin-related protein, biological_process unknown, molecular_function unknown, cell YKR024C 0.763251 INESSENTIAL DBP7 putative RNA helicase, 35S primary transcript processing*, ATP dependent RNA helicase, nucleolus YDL009C 0.759098 INESSENTIAL biological_process unknown, molecular_function unknown, YJL007C 0.751791 INESSENTIAL biological_process unknown, molecular_function unknown, YOR331C 0.745743 INESSENTIAL biological_process unknown, molecular_function unknown, YJR055W 0.740269 INESSENTIAL HIT1 involved in growth at high temperature, biological_process unknown, YKL066W 0.738361 INESSENTIAL biological_process unknown, molecular_function unknown, YNL315C 0.705923 INESSENTIAL ATP11 F1FO ATPase assembly protein, protein complex assembly, chaperone, mitochondrial matrix YCR063W 0.696335 INESSENTIAL BUD31 G10-like protein, biological_process unknown, molecular_function unknown, cellular_component unknown YML010C-B 0.686098 INESSENTIAL biological_process unknown, molecular_function unknown, YGR272C 0.677769 INESSENTIAL biological_process unknown, molecular_function unknown, YIL116W 0.669401 INESSENTIAL HIS5 histidinol-phosphate aminotransferase, histidine biosynthesis, histidinol-phosphate aminotransferase, cell YJR044C 0.665805 INESSENTIAL biological_process unknown, molecular_function unknown, YML062C 0.654095 INESSENTIAL MFT1 mitochondrial targeting protein, protein-mitochondrial targeting, molecular_function unknown, nucleus YBR282W 0.620551 INESSENTIAL MRPL27 Mitochondrial ribosomal protein MRPL27 (YmL27), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YJL188C 0.572994 INESSENTIAL BUD19 biological_process unknown, molecular_function unknown, YLR054C 0.572118 INESSENTIAL biological_process unknown, molecular_function unknown, YCR081W 0.513607 INESSENTIAL SRB8 RNA polymerase II mediator subunit, repression of transcription from Pol II promoter, RNA polymerase II transcription mediator, transcription factor complex YOR147W 0.487408 INESSENTIAL biological_process unknown, molecular_function unknown, YLR092W 0.478344 INESSENTIAL SUL2 high affinity sulfate permease, transport, YMR169C 0.473334 INESSENTIAL ALD3 aldehyde dehydrogenase, stress response, aldehyde dehydrogenase, cytoplasm YMR228W 0.460118 INESSENTIAL MTF1 Mitochondrial RNA polymerase specificity factor, transcription from mitochondrial promoter, transcription factor, mitochondrial matrix YDR462W 0.447172 INESSENTIAL MRPL28 Mitochondrial ribosomal protein MRPL28 (YmL28), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YBR268W 0.440473 INESSENTIAL MRPL37 Probable mitochondrial protein L37, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YPL101W 0.438330 INESSENTIAL biological_process unknown, molecular_function unknown, YGL167C 0.428936 INESSENTIAL PMR1 Ca++-Pump, ATPase, transport, YMR269W 0.425768 INESSENTIAL biological_process unknown, molecular_function unknown, YLR320W 0.421950 INESSENTIAL biological_process unknown, molecular_function unknown, YNL012W 0.415183 INESSENTIAL SPO1 encodes a protein with high similarity to phospholipase B, meiosis, phospholipase, nucleus YOR187W 0.402862 INESSENTIAL TUF1 Translation elongation factor Tu, mitochondrial YHR147C 0.390503 INESSENTIAL MRPL6 Mitochondrial ribosomal protein MRPL6 (YmL6), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YPL005W 0.367579 INESSENTIAL biological_process unknown, molecular_function unknown, YBR194W 0.354209 INESSENTIAL biological_process unknown, molecular_function unknown, cytoplasm YNL138W 0.334692 INESSENTIAL SRV2 70-kDa adenylyl cyclase-associated protein, cytoskeleton organization and biogenesis*, cytoskeletal protein binding protein*, actin cortical patch (sensu Saccharomyces) YGR249W 0.308795 INESSENTIAL MGA1 Mga1p shows similarity to heat shock transcription factor,molecular_function unknown, YDR056C 0.307999 INESSENTIAL biological_process unknown, molecular_function unknown, YLR098C 0.291497 INESSENTIAL CHA4 DNA-binding transcriptional activator or CHA1 YJR090C 0.288517 INESSENTIAL GRR1 cyclin F box protein, ubiquitin-dependent protein degradation*, ubiquitin--protein ligase*, nuclear ubiquitin ligase complex YBR279W 0.284900 INESSENTIAL PAF1 RNA polymerase II-associated protein, transcription, YKL003C 0.276988 INESSENTIAL MRP17 Mitochondrial ribosomal protein MRP17, protein biosynthesis, structural protein of ribosome, mitochondrial small ribosomal-subunit YJR074W 0.250252 INESSENTIAL MOG1 nuclear protein that interacts with GTP-Gsp1p, biological_process unknown, molecular_function unknown, YDL020C 0.246161 INESSENTIAL RPN4 ubiquitin-mediated 26S proteasome subunit, ubiquitin-dependent protein degradation, multicatalytic endopeptidase, 19S proteasome regulatory particle YGL071W 0.234428 INESSENTIAL RCS1 Putative transcription factor that binds the consensus site PyPuCACCCPu, iron transport, YMR193W 0.230470 INESSENTIAL MRPL24 Mitochondrial ribosomal protein MRPL24 (YmL24), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YKR092C 0.213493 INESSENTIAL SRP40 nucleolar protein that is immunologically and structurally related to rat Nopp140, a nonribosomal protein of the nucleolus and coiled bodies., nucleocytoplasmic transport, chaperone, nucleolus YGL035C 0.213255 INESSENTIAL MIG1 C2H2 zinc finger protein which resembles the mammalian Egr and Wilms tumour proteins, transcription regulation from Pol II promoter*, transcription co-repressor*, nucleus* YNL146W 0.192506 INESSENTIAL biological_process unknown, molecular_function unknown, YCR084C 0.188053 INESSENTIAL TUP1 glucose repression regulatory protein, exhibits similarity to beta subunits of G proteins, transcription, YDR338C 0.184394 INESSENTIAL biological_process unknown, molecular_function unknown, YDL107W 0.176711 INESSENTIAL MSS2 cox1 pre-mRNA splicing factor,molecular_function unknown, YNL220W 0.173303 INESSENTIAL ADE12 adenylosuccinate synthetase,adenylosuccinate synthase, YMR304C-A 0.172520 INESSENTIAL biological_process unknown, molecular_function unknown, YIR028W 0.167831 INESSENTIAL DAL4 allantoin permease,allantoin permease, YOL009C 0.164884 INESSENTIAL MDM12 Mdm12p is a mitochondrial outer membrane protein. An Mdm12p homolog exists in S. Pombe which confers a dominant negative phenotype when expressed in S. cerevisiae, mitochondrion inheritance*, molecular_function unknown, mitochondrial outer membrane YBR112C 0.164079 INESSENTIAL CYC8 Transcription regulatory protein, transcription, YLR083C 0.157326 INESSENTIAL EMP70 endosomal membrane protein YER050C 0.154344 INESSENTIAL RSM18 protein of the small subunit of the mitochondrial ribosome YNL079C 0.150507 INESSENTIAL TPM1 tropomyosin I, establishment of cell polarity (sensu Saccharomyces)*, actin lateral binding, cytokinetic ring (sensu Saccharomyces)* YGR101W 0.150253 INESSENTIAL biological_process unknown, molecular_function unknown, YLR047C 0.143246 INESSENTIAL biological_process unknown, molecular_function unknown, YLR090W 0.123755 INESSENTIAL XDJ1 Homolog of E. coli DnaJ, biological_process unknown, molecular_function unknown, YLR044C 0.120868 INESSENTIAL PDC1 pyruvate decarboxylase,alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, YGR008C 0.118519 INESSENTIAL STF2 ATPase stabilizing factor, ATP synthesis coupled proton transport, molecular_function unknown, hydrogen-transporting ATP synthase YLR370C 0.113049 INESSENTIAL ARC18 Arp2 3 Complex Subunit, actin filament organization, structural protein of cytoskeleton, Arp2/3 protein complex YDR136C 0.112130 INESSENTIAL biological_process unknown, molecular_function unknown, YML020W 0.100744 INESSENTIAL biological_process unknown, molecular_function unknown, YPL161C 0.072131 INESSENTIAL BEM4 Involved in polarity establishment and bud emergence, establishment of cell polarity (sensu Saccharomyces)*, molecular_function unknown, cellular_component unknown YPL073C 0.053073 INESSENTIAL biological_process unknown, molecular_function unknown, YPL040C 0.046884 INESSENTIAL ISM1 nuclear encoded mitochondrial isoleucyl-tRNA synthetase,isoleucine--tRNA ligase, YLR084C 0.044223 INESSENTIAL RAX2 YLR084C, maintenance of cell polarity (sensu Saccharomyces),bud neck YNL119W 0.037276 INESSENTIAL biological_process unknown, molecular_function unknown, YGR112W 0.031914 INESSENTIAL SHY1 mitochondrial protein with homology to the mammalian SURF-1 gene, respiration, molecular_function unknown, mitochondrial inner membrane YDR446W 0.021718 INESSENTIAL ECM11 (putative) involved in cell wall biogenesis,molecular_function unknown, YLR371W 0.014169 INESSENTIAL ROM2 GDP-GTP Exchange Protein (GEP) for Rho1p, establishment of cell polarity (sensu Saccharomyces)*, signal transducer*, bud tip YFR044C 0.012805 INESSENTIAL biological_process unknown, molecular_function unknown, YOR001W 0.007609 INESSENTIAL RRP6 involved in 5.8S rRNA processing, 35S primary transcript processing, 3'-5' exoribonuclease, nuclear exosome (RNase complex) YER014C-A 0.005807 INESSENTIAL BUD25 bud site selection, biological_process unknown, molecular_function unknown, cellular_component unknown YLR068W -0.003054 INESSENTIAL FYV7 biological_process unknown, molecular_function unknown, cellular_component unknown YNL025C -0.014091 INESSENTIAL SSN8 C-type cyclin associated with the Ssn3p cyclin-dependent kinase, repression of transcription from Pol II promoter, non-specific RNA polymerase II transcription factor*, transcription factor complex YDR127W -0.016596 INESSENTIAL ARO1 pentafunctional arom polypeptide (contains: 3-dehydroquinate synthase, 3-dehydroquinate dehydratase (3-dehydroquinase), shikimate 5-dehydrogenase, shikimate kinase, and epsp synthase),3-dehydroquinate dehydratase, YPR100W -0.017597 INESSENTIAL biological_process unknown, molecular_function unknown, YNL153C -0.034119 INESSENTIAL GIM3 bovine prefoldin subunit 4 homolog (putative), protein folding, YCL047C -0.042023 INESSENTIAL biological_process unknown, molecular_function unknown, YHR115C -0.052933 INESSENTIAL biological_process unknown, molecular_function unknown, YDR264C -0.061947 INESSENTIAL AKR1 Ankyrin repeat-containing protein, endocytosis*, molecular_function unknown, cellular_component unknown YLR444C -0.092651 INESSENTIAL biological_process unknown, molecular_function unknown, YLR150W -0.099714 INESSENTIAL STM1 gene product has affinity for quadruplex nucleic acids, biological_process unknown, molecular_function unknown, YGL019W -0.106732 INESSENTIAL CKB1 beta (38kDa) subunit of casein kinase II (CKII), establishment of cell polarity (sensu Saccharomyces)*, casein kinase II, casein kinase II YLR048W -0.115628 INESSENTIAL RPS0B Ribosomal protein S0B, protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YLR312W-A -0.126085 INESSENTIAL MRPL15 Mitochondrial ribosomal protein MRPL15 (YmL15), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YER066C-A -0.145762 INESSENTIAL biological_process unknown, molecular_function unknown, YMR012W -0.164507 INESSENTIAL CLU1 translation initiation factor eIF3 subunit, protein synthesis initiation*, translation initiation factor, ribosome* YLR388W -0.175238 INESSENTIAL RPS29A Ribosomal protein S29A (S36A) (YS29), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YAR031W -0.177832 INESSENTIAL PRM9 membrane protein, mating (sensu Saccharomyces), molecular_function unknown, integral membrane protein YCR092C -0.185873 INESSENTIAL MSH3 mutS homolog, forms a complex with Msh2p to repair insertion-deletion mispairs; redundant with Pms3 Msh6p in repair of insertion-deletion mispairs YIR026C -0.193546 INESSENTIAL YVH1 nitrogen starvation-induced protein phosphatase, meiosis*, protein tyrosine phosphatase, YKR035C -0.212241 INESSENTIAL biological_process unknown, molecular_function unknown, YDL151C -0.226963 INESSENTIAL FYV3 biological_process unknown, molecular_function unknown, cellular_component unknown YNL109W -0.268461 INESSENTIAL biological_process unknown, molecular_function unknown, YLR357W -0.270659 INESSENTIAL RSC2 Member of RSC complex., chromatin modeling, molecular_function unknown, nucleosome remodeling complex YAL044C -0.280195 INESSENTIAL GCV3 H-protein subunit of the glycine cleavage system, glycine metabolism, YKL213C -0.283478 INESSENTIAL DOA1 phospholipase A2-activating protein, ubiquitin-dependent protein degradation, molecular_function unknown, cellular_component unknown YCL029C -0.299398 INESSENTIAL BIK1 Microtubule-binding protein, mitotic anaphase B*, microtubule binding, spindle pole body* YOR026W -0.307502 INESSENTIAL BUB3 cell cycle checkpoint protein, mitotic spindle checkpoint, molecular_function unknown, cellular_component unknown YOL007C -0.334847 INESSENTIAL CSI2 Appears to be a structural component of the chitin synthase 3 complex YLR260W -0.345416 INESSENTIAL LCB5 sphingoid long chain base (LCB) kinase, sphingolipid metabolism, YIL100W -0.354806 INESSENTIAL biological_process unknown, molecular_function unknown, YML094W -0.365282 INESSENTIAL GIM5 bovine prefoldin subunit 5 homolog (putative), protein folding, YMR008C -0.368968 INESSENTIAL PLB1 Phospholipase B (lypophospholipase),lysophospholipase, YHL025W -0.371246 INESSENTIAL SNF6 subunit of the chromatin remodeling Snf Swi complex, chromatin modeling, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex YDR298C -0.388118 INESSENTIAL ATP5 ATP synthase subunit 5; oligomycin sensitivity-conferring protein, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, stator stalk YMR312W -0.397254 INESSENTIAL biological_process unknown, molecular_function unknown, YDL202W -0.400233 INESSENTIAL MRPL11 Mitochondrial ribosomal protein MRPL11 (YmL11), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YBL043W -0.401021 INESSENTIAL ECM13 (putative) involved in cell wall biogenesis,molecular_function unknown, YDR175C -0.404664 INESSENTIAL RSM24 protein of the small subunit of the mitochondrial ribosome YOR199W -0.412937 INESSENTIAL biological_process unknown, molecular_function unknown, YNL320W -0.417048 INESSENTIAL biological_process unknown, molecular_function unknown, YNL069C -0.423756 INESSENTIAL RPL16B Ribosomal protein L16B (L21B) (rp23) (YL15), protein biosynthesis, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YLR042C -0.427708 INESSENTIAL biological_process unknown, molecular_function unknown, YJL013C -0.427846 INESSENTIAL MAD3 spindle checkpoint complex subunit, mitotic spindle checkpoint, molecular_function unknown, nucleus YMR098C -0.429457 INESSENTIAL biological_process unknown, molecular_function unknown, YMR244C-A -0.433344 INESSENTIAL biological_process unknown, molecular_function unknown, YCR024C -0.433589 INESSENTIAL Asn-tRNA synthetase, protein biosynthesis, asparagine--tRNA ligase*, mitochondrion YNR006W -0.444544 INESSENTIAL VPS27 hydrophilic protein; has cysteine rich putative zinc finger esential for function YGR206W -0.447146 INESSENTIAL biological_process unknown, molecular_function unknown, YPL106C -0.456620 INESSENTIAL SSE1 HSP70 family member, highly homologous to Ssa1p and Sse2p, protein folding, cochaperone, cytoplasm YMR141C -0.463460 INESSENTIAL biological_process unknown, molecular_function unknown, YJL168C -0.464634 INESSENTIAL SET2 transcription factor containing a SET domain YCR044C -0.476864 INESSENTIAL PER1 Protein Processing in the ER,molecular_function unknown, YOR054C -0.479918 INESSENTIAL biological_process unknown, molecular_function unknown, YHR193C -0.511713 INESSENTIAL EGD2 GAL4 enhancer protein, homolog of human alpha NAC subunit of the nascent-polypeptide-associated complex, nascent polypeptide association, chaperone, nascent polypeptide-associated complex YLR358C -0.516968 INESSENTIAL biological_process unknown, molecular_function unknown, YDL189W -0.546217 INESSENTIAL biological_process unknown, molecular_function unknown, YPL191C -0.561579 INESSENTIAL biological_process unknown, molecular_function unknown, YLR217W -0.567763 INESSENTIAL biological_process unknown, molecular_function unknown, cellular_component unknown YBL072C -0.570738 INESSENTIAL RPS8A Ribosomal protein S8A (S14A) (rp19) (YS9), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDR486C -0.570957 INESSENTIAL VPS60 biological_process unknown, molecular_function unknown, cellular_component unknown YBR213W -0.580670 INESSENTIAL MET8 Effector in the expression of PAPS reductase and sulfite reductase, sulfate assimilation, siroheme synthase, YIR005W -0.601531 INESSENTIAL IST3 biological_process unknown, molecular_function unknown, cellular_component unknown YGL058W -0.609132 INESSENTIAL RAD6 Ubiquitin conjugating (E2) enzyme. The C-terminal 23 residues are critical for sporulation and histone polyubiquitinating activity, but not UV repair or induced mutagenesis., ubiquitin-dependent protein degradation*, ubiquitin conjugating enzyme, nucleus YDR069C -0.611778 INESSENTIAL DOA4 ubiquitin isopeptidase, deubiquitylation*, ubiquitin-specific protease, 26S proteasome YJL140W -0.615962 INESSENTIAL RPB4 fourth-largest subunit of RNA polymerase II, transcription from Pol II promoter, DNA-directed RNA polymerase II, DNA-directed RNA polymerase II, core YDR347W -0.629823 INESSENTIAL MRP1 37 kDa mitochondrial ribosomal protein, protein biosynthesis, structural protein of ribosome, mitochondrial small ribosomal-subunit YMR097C -0.636134 INESSENTIAL biological_process unknown, molecular_function unknown, YGR221C -0.647492 INESSENTIAL TOS2 biological_process unknown, molecular_function unknown, YKL001C -0.700380 INESSENTIAL MET14 adenylylsulfate kinase, methionine metabolism*, adenylsulfate kinase, cellular_component unknown YPR111W -0.707509 INESSENTIAL DBF20 kinase required for late nuclear division, protein phosphorylation*, protein serine/threonine kinase, YGL042C -0.722812 INESSENTIAL biological_process unknown, molecular_function unknown, YGL154C -0.741559 INESSENTIAL LYS5 aminoadipate-semialdehyde dehydrogenase small subunit (alpha-aminoadipate reductase), amino acid biosynthesis, aminoadipate-semialdehyde dehydrogenase, cytoplasm YDR129C -0.742637 INESSENTIAL SAC6 fibrim homolog (actin-filament bundling protein), endocytosis*, actin cross-linking, actin cortical patch (sensu Saccharomyces)* YDR237W -0.751427 INESSENTIAL MRPL7 Mitochondrial ribosomal protein MRPL7 (YmL7), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YDR114C -0.752167 INESSENTIAL biological_process unknown, molecular_function unknown, YNL054W -0.757494 INESSENTIAL VAC7 Integral vacuolar membrane protein,molecular_function unknown, YAL023C -0.776945 INESSENTIAL PMT2 dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase, O-linked glycosylation, dolichyl-phosphate-mannose--protein mannosyltransferase, endoplasmic reticulum YIL008W -0.790230 INESSENTIAL URM1 ubiquitin like protein, protein modification, YOR352W -0.807863 INESSENTIAL biological_process unknown, molecular_function unknown, YNR055C -0.818808 INESSENTIAL HOL1 Putative ion transporter similar to the major facilitator superfamily of transporters, transport, YER122C -0.820581 INESSENTIAL GLO3 Zinc-finger-containing protein with similarity to Gcs1p and Sps18p, ER to Golgi transport*, ARF GTPase activator, secretory vesicle* YJR144W -0.825926 INESSENTIAL MGM101 (putative) nucleic acid interactor, mitochondrial genome maintenance, YMR280C -0.835323 INESSENTIAL CAT8 Zinc-cluster protein involved in activating gluconeogenic genes; related to Gal4p, gluconeogenesis, transcription factor, YMR205C -0.853518 INESSENTIAL PFK2 phosphofructokinase beta subunit, glycolysis, 6-phosphofructokinase, 6-phosphofructokinase YLL018C-A -0.860470 INESSENTIAL COX19 Cox19p (under characterization),molecular_function unknown, YJL029C -0.870644 INESSENTIAL VPS53 Vps53p is a hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p.,molecular_function unknown, YPR125W -0.872157 INESSENTIAL biological_process unknown, YGL105W -0.888968 INESSENTIAL ARC1 G4 nucleic acid binding protein, involved in tRNA aminoacylation YMR188C -0.889166 INESSENTIAL biological_process unknown, molecular_function unknown, YNR005C -0.890583 INESSENTIAL biological_process unknown, molecular_function unknown, YLR123C -0.894479 INESSENTIAL biological_process unknown, molecular_function unknown, YDR377W -0.912787 INESSENTIAL ATP17 ATP synthase subunit f, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, F0 sector YIL049W -0.932598 INESSENTIAL DFG10 involved in filamentous growth,molecular_function unknown, YAL056W -0.937224 INESSENTIAL G protein effector, biological_process unknown, molecular_function unknown, YIL065C -0.941322 INESSENTIAL FIS1 mitochondrial fission, mitochondrial fission, molecular_function unknown, mitochondrial outer membrane YGL138C -0.949019 INESSENTIAL biological_process unknown, molecular_function unknown, YCR090C -0.961957 INESSENTIAL biological_process unknown, molecular_function unknown, YPL223C -0.965676 INESSENTIAL GRE1 hydrophilic polypeptide with no known homology, biological_process unknown, molecular_function unknown, YKR078W -0.976937 INESSENTIAL biological_process unknown, molecular_function unknown, YPL090C -0.977942 INESSENTIAL RPS6A Ribosomal protein S6A (S10A) (rp9) (YS4), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YGR076C -0.981943 INESSENTIAL MRPL25 Mitochondrial ribosomal protein MRPL25 (YmL25), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YMR286W -0.989511 INESSENTIAL MRPL33 Mitochondrial ribosomal protein MRPL33 (YmL33) (E. coli L30), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YML068W -0.990106 INESSENTIAL biological_process unknown, molecular_function unknown, YDL032W -1.013546 INESSENTIAL biological_process unknown, molecular_function unknown, YGR016W -1.018464 INESSENTIAL biological_process unknown, molecular_function unknown, YML081W -1.019958 INESSENTIAL biological_process unknown, molecular_function unknown, YGL127C -1.022846 INESSENTIAL SOH1 SOH1 encodes a novel 14-kD protein with limited sequence similarity to RNA polymerases. The Soh1 protein interacts with a DNA repair protein, Rad5p, in a two-hybrid system assay., biological_process unknown, molecular_function unknown, YJL106W -1.030113 INESSENTIAL IME2 Serine Threonine protein kinase, positively regulated by IME1 YLR053C -1.037296 INESSENTIAL biological_process unknown, molecular_function unknown, YJR118C -1.041536 INESSENTIAL ILM1 molecular_function unknown YDL223C -1.065093 INESSENTIAL biological_process unknown, molecular_function unknown, YGL010W -1.070464 INESSENTIAL biological_process unknown, molecular_function unknown, YML122C -1.077796 INESSENTIAL biological_process unknown, molecular_function unknown, YHR100C -1.082378 INESSENTIAL biological_process unknown, molecular_function unknown, YJR050W -1.083521 INESSENTIAL ISY1 interacts with the spliceosome, mRNA splicing, molecular_function unknown, spliceosome YDL019C -1.100588 INESSENTIAL OSH2 OSbp Homologue (OSBP stands for Oxysterol binding protein), biological_process unknown, molecular_function unknown, YLR404W -1.102422 INESSENTIAL biological_process unknown, molecular_function unknown, YDR458C -1.108448 INESSENTIAL biological_process unknown, molecular_function unknown, YMR142C -1.109539 INESSENTIAL RPL13B Ribosomal protein L13B, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YLR399C -1.115043 INESSENTIAL BDF1 Bdf1p contains two bromodomains, localizes to the nucleus and to chomosomes in spread meiotic nuclei but is excluded from the nucleolus, sporulation (sensu Saccharomyces), transcription factor, nucleus YPR133W-A -1.115241 INESSENTIAL TOM5 Membrane protein involved in protein translocation to the mitochondria, mitochondrial translocation, protein transporter, mitochondrial outer membrane translocase complex YML061C -1.115855 INESSENTIAL PIF1 5' to 3' DNA helicase, DNA recombination*, DNA helicase, mitochondrion YFR010W -1.116920 INESSENTIAL UBP6 (putative) ubiquitin-specific protease, deubiquitylation, ubiquitin-specific protease, cellular_component unknown YNR036C -1.119585 INESSENTIAL biological_process unknown, molecular_function unknown, YIL146C -1.139284 INESSENTIAL ECM37 (putative) involved in cell wall biogenesis,molecular_function unknown, YEL023C -1.139550 INESSENTIAL biological_process unknown, molecular_function unknown, YGR070W -1.151193 INESSENTIAL ROM1 Rho1 GDP GTP exchange protein, establishment of cell polarity (sensu Saccharomyces)*, signal transducer*, intracellular YGR219W -1.153715 INESSENTIAL biological_process unknown, molecular_function unknown, YOR099W -1.170182 INESSENTIAL KTR1 type 2 membrane protein; probable secretory protein, O-linked glycosylation*, alpha-1,2-mannosyltransferase, Golgi apparatus YHR039C -1.171959 INESSENTIAL MSC7 Aldehyde dehydrogenases, biological_process unknown, molecular_function unknown, YDR137W -1.173254 INESSENTIAL RGP1 involved in mitotic growth, biological_process unknown, molecular_function unknown, YLR396C -1.188145 INESSENTIAL VPS33 involved in vacuolar protein targeting YGL038C -1.194469 INESSENTIAL OCH1 membrane-bound alpha-1,6-mannosyltransferase, N-linked glycoprotein maturation, alpha-1,6-mannosyltransferase, YLR425W -1.197424 INESSENTIAL TUS1 1307 AA, hydrophilic protein., biological_process unknown, molecular_function unknown, YMR287C -1.202603 INESSENTIAL MSU1 component of 3'-5'exonuclease complex YER017C -1.211284 INESSENTIAL AFG3 ATP-dependent metalloprotease, protein complex assembly*, adenosinetriphosphatase*, mitochondrial inner membrane YLR360W -1.223000 INESSENTIAL VPS38 involved in vacuolar protein targeting,molecular_function unknown, YLR435W -1.227835 INESSENTIAL biological_process unknown, molecular_function unknown, YOR083W -1.233346 INESSENTIAL biological_process unknown, molecular_function unknown, YBR296C -1.238127 INESSENTIAL PHO89 Probable Na+ Pi symporter, phosphate metabolism, YER049W -1.241216 INESSENTIAL biological_process unknown, molecular_function unknown, cellular_component unknown YKR035W-A -1.259762 INESSENTIAL DID2 Rad52p inhibitor YGR162W -1.263519 INESSENTIAL TIF4631 mRNA cap-binding protein (eIF-4F), 150K subunit , highly homologous to Tif4632p, homologs of mammalian p220, protein synthesis initiation, translation initiation factor, ribosome YNL210W -1.265977 INESSENTIAL MER1 encodes protein with RNA-binding motifs required for MRE2-dependent mRNA splicing, meiosis, pre-mRNA splicing factor, nucleus YNL063W -1.277317 INESSENTIAL biological_process unknown, molecular_function unknown, YDR281C -1.283806 INESSENTIAL PHM6 phosphate metabolism; transcription is regulated by PHO system,molecular_function unknown, YLR384C -1.288827 INESSENTIAL IKI3 required for killer toxin sensitivity,molecular_function unknown, YHR041C -1.313533 INESSENTIAL SRB2 RNA polymerase II holoenzyme mediator subunit, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YDL232W -1.319329 INESSENTIAL OST4 3.6-kDa protein, probably membrane-located,dolichyl-diphosphooligosaccharide-protein glycosyltransferase, YJL162C -1.326528 INESSENTIAL biological_process unknown, molecular_function unknown, YOL023W -1.337005 INESSENTIAL IFM1 mitochondrial initiation factor 2, protein synthesis initiation, translation initiation factor, mitochondrion YKL054C -1.343985 INESSENTIAL VID31 vacuole import and degradation,molecular_function unknown, YDL080C -1.361035 INESSENTIAL THI3 alpha-ketoisocaproate decarboxylase, vitamin B1 biosynthesis, transcription activating factor, cellular_component unknown YBR285W -1.361837 INESSENTIAL biological_process unknown, molecular_function unknown, YDR529C -1.364444 INESSENTIAL QCR7 ubiquinol-cytochrome c oxidoreductase subunit 7 (14 kDa),ubiquinol-cytochrome-c reductase, YDL115C -1.367477 INESSENTIAL biological_process unknown, molecular_function unknown, YGR157W -1.370343 INESSENTIAL CHO2 Phosphatidyl-ethanolamine N-methyltransferase, phosphatidylcholine biosynthesis, methylene-fatty-acyl-phospholipid synthase, endoplasmic reticulum YGR054W -1.371727 INESSENTIAL biological_process unknown, molecular_function unknown, YNL185C -1.382733 INESSENTIAL MRPL19 mitochondrial ribosomal protein of the large subunit, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YPR174C -1.405594 INESSENTIAL biological_process unknown, molecular_function unknown, YBR003W -1.413754 INESSENTIAL COQ1 hexaprenyl pyrophosphate synthetase, ubiquinone metabolism, trans-hexaprenyltranstransferase, YOR382W -1.417293 INESSENTIAL FIT2 biological_process unknown, molecular_function unknown, YGR210C -1.420448 INESSENTIAL biological_process unknown, molecular_function unknown, YMR184W -1.426926 INESSENTIAL biological_process unknown, molecular_function unknown, YGL164C -1.427853 INESSENTIAL biological_process unknown, molecular_function unknown, YML024W -1.435227 INESSENTIAL RPS17A Ribosomal protein S17A (rp51A), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YOR196C -1.435885 INESSENTIAL LIP5 lipoic acid synthase, fatty acid metabolism, YLR343W -1.445134 INESSENTIAL biological_process unknown, molecular_function unknown, YMR031C -1.446180 INESSENTIAL biological_process unknown, molecular_function unknown, YDR073W -1.454141 INESSENTIAL SNF11 component of SWI SNF global transcription activator complex, chromatin modeling, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex YDR079W -1.469059 INESSENTIAL PET100 cytochrome c oxidase-specific assembly factor, cytochrome c oxidase biogenesis, molecular_function unknown, cellular_component unknown YLR119W -1.469957 INESSENTIAL SRN2 may be involved in RNA export from nucleus,molecular_function unknown, YDR405W -1.476248 INESSENTIAL MRP20 263-amino acid mitochondrial ribosomal large subunit protein; similar to L23 family of ribosomal proteins, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YHL011C -1.477407 INESSENTIAL PRS3 ribose-phosphate pyrophosphokinase 3, histidine biosynthesis*, ribose-phosphate pyrophosphokinase, cytoplasm YDR382W -1.488269 INESSENTIAL RPP2B Ribosomal protein P2B (YP2beta) (L45), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YMR014W -1.502588 INESSENTIAL BUD22 BUD site selection, biological_process unknown, molecular_function unknown, YBR111C -1.504751 INESSENTIAL YSA1 Homolog to serendipity protein (D. melanogaster), biological_process unknown, molecular_function unknown, YGL051W -1.510766 INESSENTIAL biological_process unknown, molecular_function unknown, YIL015C-A -1.512721 INESSENTIAL biological_process unknown, molecular_function unknown, YFR032C-A -1.515657 INESSENTIAL RPL29 Ribosomal protein L29 (YL43), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YBL033C -1.537430 INESSENTIAL RIB1 GTP cyclohydrolase II,GTP cyclohydrolase II, YGL131C -1.546932 INESSENTIAL biological_process unknown, molecular_function unknown, YPL032C -1.549442 INESSENTIAL SVL3 (putative) involved in vacuole function, endocytosis, molecular_function unknown, cellular_component unknown YCL037C -1.551206 INESSENTIAL SRO9 RNA binding protein with La motif YBL021C -1.566052 INESSENTIAL HAP3 transcriptional activator protein of CYC1, transcription, YDR378C -1.569121 INESSENTIAL LSM6 Sm-like protein,molecular_function unknown, YGL140C -1.570815 INESSENTIAL biological_process unknown, YMR116C -1.576417 INESSENTIAL ASC1 G-beta like protein YEL029C -1.594026 INESSENTIAL BUD16 biological_process unknown, molecular_function unknown, YIL079C -1.613348 INESSENTIAL biological_process unknown, molecular_function unknown, YOL056W -1.620271 INESSENTIAL GPM3 phosphoglycerate mutase, glycolysis*, phosphoglycerate mutase, cytosol YLR216C -1.630008 INESSENTIAL CPR6 cyclophilin related to the mammalian CyP-40, protein folding, peptidylprolyl isomerase, cytoplasm YBL024W -1.633956 INESSENTIAL NCL1 Probable proliferating-cell nucleolar antigen (human p120), biological_process unknown, molecular_function unknown, YMR025W -1.660385 INESSENTIAL biological_process unknown, molecular_function unknown, YDR061W -1.665890 INESSENTIAL biological_process unknown, molecular_function unknown, YNL156C -1.680794 INESSENTIAL biological_process unknown, molecular_function unknown, YGR233C -1.689254 INESSENTIAL PHO81 Pho85 kinase inhibitor, cell cycle, YMR024W -1.695468 INESSENTIAL MRPL3 Mitochondrial ribosomal protein MRPL3 (YmL3), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YGR161C -1.710049 INESSENTIAL biological_process unknown, molecular_function unknown, YDL024C -1.712544 INESSENTIAL DIA3 Digs Into Agar, pseudohyphal growth*, acid phosphatase, cellular_component unknown YOR267C -1.718544 INESSENTIAL biological_process unknown, YJL172W -1.722396 INESSENTIAL CPS1 carboxypeptidase yscS,gly-X carboxypeptidase, YOL100W -1.730987 INESSENTIAL PKH2 Ser Thr protein kinase, biological_process unknown, YMR053C -1.738671 INESSENTIAL STB2 Sin3p binding protein, biological_process unknown, YDL088C -1.741487 INESSENTIAL ASM4 Nuclear pore complex protein, mRNA-nucleus export*, structural protein, nuclear pore YIL007C -1.747686 INESSENTIAL biological_process unknown, molecular_function unknown, YHL013C -1.771203 INESSENTIAL biological_process unknown, molecular_function unknown, YKL134C -1.777874 INESSENTIAL 1 mitochondrial intermediate peptidase, possesses octapeptidyl amino-peptidase activity, iron homeostasis*, metallopeptidase, mitochondrion YDR051C -1.779927 INESSENTIAL biological_process unknown, molecular_function unknown, YLL002W -1.802030 INESSENTIAL REM50 diepoxybutane and mitomycin C resistance,molecular_function unknown, YGR034W -1.810437 INESSENTIAL RPL26B Ribosomal protein L26B (L33B) (YL33), protein biosynthesis, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YDL023C -1.821581 INESSENTIAL biological_process unknown, molecular_function unknown, YBR133C -1.823747 INESSENTIAL HSL7 regulator of Swe1p kinase, bud growth*, protein kinase inhibitor, cytokinetic ring (sensu Saccharomyces) YOR124C -1.826448 INESSENTIAL UBP2 Ubiquitin-specific protease, deubiquitylation, ubiquitin-specific protease, cytoplasm YKL100C -1.830194 INESSENTIAL biological_process unknown, molecular_function unknown, YGL218W -1.837107 INESSENTIAL biological_process unknown, molecular_function unknown, YOR043W -1.838990 INESSENTIAL WHI2 involved in growth regulation,molecular_function unknown, YKR009C -1.846024 INESSENTIAL FOX2 peroxisomal multifunctional beta-oxidation protein, fatty acid beta-oxidation, 3-hydroxyacyl-CoA dehydrogenase*, peroxisomal matrix YIL034C -1.849415 INESSENTIAL CAP2 beta subunit of capping protein, cell wall organization and biogenesis*, F-actin capping, actin cortical patch (sensu Saccharomyces)* YNL288W -1.875948 INESSENTIAL CAF40 CCR4 associated factor 40 kDa YIL029C -1.884821 INESSENTIAL biological_process unknown, molecular_function unknown, YDR375C -1.912530 INESSENTIAL BCS1 Mitochondrial ATPase (AAA family), respiration, adenosinetriphosphatase, mitochondrial inner membrane YML097C -1.913758 INESSENTIAL VPS9 similar to mammalian ras inhibitors YLR107W -1.925992 INESSENTIAL REX3 RNA EXonuclease; part of family of 3'-to5' exonucleases. See Moser et al. 1997 Nucleic acids Res. 25:5110-5118, RNA processing, 3'-5' exonuclease, cellular_component unknown YDR332W -1.926564 INESSENTIAL biological_process unknown, molecular_function unknown, YLR148W -1.941003 INESSENTIAL PEP3 vacuolar membrane protein YGL070C -1.945720 INESSENTIAL RPB9 RNA polymerase II subunit, transcription from Pol II promoter, DNA-directed RNA polymerase II, DNA-directed RNA polymerase II, core YKL170W -1.954455 INESSENTIAL MRPL38 mitochondrial ribosomal protein L14, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YIL087C -1.955835 INESSENTIAL biological_process unknown, molecular_function unknown, YNR032C-A -1.969160 INESSENTIAL HUB1 ubiquitin-like modifier YOR304W -1.970094 INESSENTIAL ISW2 ATPase component of a two subunit chromatin remodeling complex, biological_process unknown, molecular_function unknown, YMR004W -1.974714 INESSENTIAL MVP1 peripheral Golgi membrane protein YML053C -1.982241 INESSENTIAL biological_process unknown, molecular_function unknown, YPR070W -1.983999 INESSENTIAL MED1 Subunit 1 of the Mediator complex essential for transcriptional regulation, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YDR158W -1.985688 INESSENTIAL HOM2 aspartic beta semi-aldehyde dehydrogenase,aspartate-semialdehyde dehydrogenase, YMR181C -1.992949 INESSENTIAL biological_process unknown, molecular_function unknown, YGR144W -1.999944 INESSENTIAL THI4 component of the biosynthetic pathway producing the thiazole precursor of thiamine, DNA repair*, molecular_function unknown, mitochondrion YOR305W -2.017887 INESSENTIAL biological_process unknown, molecular_function unknown, YDR074W -2.023480 INESSENTIAL TPS2 Trehalose-6-phosphate phosphatase, stress response*, trehalose phosphatase, alpha,alpha-trehalose-phosphate synthase (UDP-forming) YJR056C -2.024926 INESSENTIAL biological_process unknown, molecular_function unknown, YPL257W -2.027098 INESSENTIAL biological_process unknown, molecular_function unknown, YDR024W -2.027182 INESSENTIAL FYV1 biological_process unknown, molecular_function unknown, cellular_component unknown YBR159W -2.027631 INESSENTIAL biological_process unknown, molecular_function unknown, YOR279C -2.037778 INESSENTIAL biological_process unknown, molecular_function unknown, YGL158W -2.039161 INESSENTIAL RCK1 Serine threonine protein kinase, biological_process unknown, protein kinase, YMR075C-A -2.054638 INESSENTIAL biological_process unknown, molecular_function unknown, YDL123W -2.064948 INESSENTIAL biological_process unknown, molecular_function unknown, YGR027C -2.096854 INESSENTIAL RPS25A Ribosomal protein S25A (S31A) (rp45) (YS23), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YNL013C -2.098631 INESSENTIAL biological_process unknown, molecular_function unknown, YGR134W -2.099528 INESSENTIAL CAF130 CCR4 associated factor 130 kDa YER053C -2.109123 INESSENTIAL biological_process unknown, inorganic phosphate transporter, vacuole YKR085C -2.116549 INESSENTIAL MRPL20 22.3 kDa mitochondrial ribosomal large subunit protein YmL20; homologous to L17 of E. coli, protein biosynthesis*, structural protein of ribosome, mitochondrial large ribosomal-subunit YIL069C -2.119021 INESSENTIAL RPS24B 40S ribosomal protein S24B, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YER016W -2.125618 INESSENTIAL BIM1 microtubule-binding protein, microtubule nucleation*, structural protein of cytoskeleton, spindle pole body* YJL093C -2.143135 INESSENTIAL TOK1 outward-rectifier potassium channel, transport, YNL252C -2.157519 INESSENTIAL MRPL17 mitochondrial ribosomal protein of the large subunit, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YGR110W -2.181012 INESSENTIAL biological_process unknown, molecular_function unknown, YEL049W -2.189892 INESSENTIAL PAU2 similar to members of the seripauperin (PAU) family, biological_process unknown, molecular_function unknown, YNL330C -2.209843 INESSENTIAL RPD3 histone deacetylase, chromatin architecture*, histone deacetylase, histone deacetylase complex YGL205W -2.212917 INESSENTIAL POX1 fatty-acyl coenzyme A oxidase, fatty acid beta-oxidation, acyl-CoA oxidase, peroxisomal matrix YIL055C -2.221022 INESSENTIAL biological_process unknown, molecular_function unknown, YJR019C -2.243011 INESSENTIAL TES1 peroxisomal acyl-CoA thioesterase, fatty acid metabolism, YPL155C -2.247052 INESSENTIAL KIP2 kinesin-related protein, mitotic anaphase B*, microtubule motor, cytoplasmic microtubule* YHR022C -2.262613 INESSENTIAL RAS-related protein, biological_process unknown, molecular_function unknown, YGR123C -2.303284 INESSENTIAL PPT1 serine threonine phosphatase,protein serine/threonine phosphatase, YLR328W -2.312978 INESSENTIAL biological_process unknown, molecular_function unknown, YJL133W -2.316848 INESSENTIAL MRS3 mitochondrial carrier protein, transport*, carrier, mitochondrion YHR111W -2.348163 INESSENTIAL moeB, thiF, UBA1, biological_process unknown, molecular_function unknown, YIL053W -2.358912 INESSENTIAL RHR2 DL-glycerol-3-phosphatase, glycerol metabolism, YGR089W -2.365648 INESSENTIAL biological_process unknown, molecular_function unknown, YAR029W -2.379860 INESSENTIAL membrane protein, biological_process unknown, molecular_function unknown, YKL208W -2.395641 INESSENTIAL CBT1 involved in RNA splicing,molecular_function unknown, YBR271W -2.401034 INESSENTIAL biological_process unknown, molecular_function unknown, YKL015W -2.421583 INESSENTIAL PUT3 zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, transcription, YLL044W -2.433860 INESSENTIAL biological_process unknown, molecular_function unknown, YIL073C -2.435899 INESSENTIAL SPO22 meiosis-specific phospholipase A2 homolog YLR279W -2.436675 INESSENTIAL biological_process unknown, molecular_function unknown, YOL068C -2.476361 INESSENTIAL HST1 Homolog of SIR2 YIL056W -2.496243 INESSENTIAL biological_process unknown, molecular_function unknown, YCR015C -2.501433 INESSENTIAL biological_process unknown, molecular_function unknown, YKL138C -2.503664 INESSENTIAL MRPL31 15.5 kDa mitochondrial ribosomal protein YmL31, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YER106W -2.538682 INESSENTIAL MAM1 biological_process unknown, molecular_function unknown, YNL046W -2.541721 INESSENTIAL biological_process unknown, molecular_function unknown, YMR072W -2.552217 INESSENTIAL ABF2 HMG-1 homolog, mitochondrial, mitochondrial genome maintenance, YMR009W -2.553676 INESSENTIAL biological_process unknown, molecular_function unknown, YJL169W -2.555809 INESSENTIAL biological_process unknown, molecular_function unknown, YHR125W -2.577662 INESSENTIAL biological_process unknown, molecular_function unknown, YOL052C -2.581688 INESSENTIAL SPE2 S-adenosylmethionine decarboxylase,adenosylmethionine decarboxylase, YML052W -2.591079 INESSENTIAL SUR7 putative integral membrane protein YDR497C -2.620900 INESSENTIAL ITR1 myo-inositol transporter, transport, YOR005C -2.625995 INESSENTIAL DNL4 ATP dependent DNA ligase, double-strand break repair via nonhomologous end-joining, DNA ligase (ATP), nucleus YPL263C -2.646148 INESSENTIAL KEL3 Kelch-repeat protein, similar to Kel1 and Kel2, biological_process unknown, molecular_function unknown, YMR111C -2.685399 INESSENTIAL biological_process unknown, molecular_function unknown, YDR102C -2.692529 INESSENTIAL biological_process unknown, molecular_function unknown, YML060W -2.707820 INESSENTIAL OGG1 43-kDa 8-oxo-guanine DNA glycosylase, DNA repair, 8-oxoguanine DNA glycosylase, YAL005C -2.748706 INESSENTIAL SSA1 Heat shock protein of HSP70 family, cytoplasmic, protein folding*, adenosinetriphosphatase*, nucleus* YOR141C -2.749063 INESSENTIAL ARP8 actin-related protein, biological_process unknown, molecular_function unknown, cell YJL065C -2.774142 INESSENTIAL biological_process unknown, molecular_function unknown, YJR039W -2.776256 INESSENTIAL biological_process unknown, molecular_function unknown, YOL013C -2.776735 INESSENTIAL HRD1 required to degrade misfolded ER lumenal and integral membrane proteins,molecular_function unknown, YER164W -2.799680 INESSENTIAL CHD1 transcriptional regulator, transcription, YLR023C -2.810336 INESSENTIAL biological_process unknown, molecular_function unknown, YHR049W -2.824353 INESSENTIAL biological_process unknown, molecular_function unknown, YGL094C -2.830377 INESSENTIAL PAN2 135-kDa protein that is subunit of poly(A) ribonuclease, mRNA processing,cellular_component unknown YMR147W -2.831300 INESSENTIAL biological_process unknown, molecular_function unknown, YAL002W -2.833244 INESSENTIAL VPS8 Vps8p is a membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the RING finger Zn2+ binding motif.,molecular_function unknown, YDR059C -2.855803 INESSENTIAL UBC5 ubiquitin-conjugating enzyme, stress response*, ubiquitin conjugating enzyme, cellular_component unknown YLR408C -2.869864 INESSENTIAL biological_process unknown, molecular_function unknown, YPR002W -2.871958 INESSENTIAL PDH1 prpD homolog (ie the propionate operon of many prokaryotes and specifically, the gene called prpD in that operon) This gene may be regarded as *real* in yeast by two criteria: it has close homologs (some known to be essential for propionate utilization) in numerous prokaryotes (several of these homologs are called prpD), and it is transcribed in yeast.,molecular_function unknown, YJR100C -2.878720 INESSENTIAL biological_process unknown, molecular_function unknown, YML050W -2.879361 INESSENTIAL biological_process unknown, molecular_function unknown, YJL079C -2.881880 INESSENTIAL PRY1 Similar to plant PR-1 class of pathogen related proteins, biological_process unknown, molecular_function unknown, YMR140W -2.913470 INESSENTIAL biological_process unknown, molecular_function unknown, YOR297C -2.915561 INESSENTIAL TIM18 mitochondrial inner memebrane translocase, protein-mitochondrial targeting*, ATP/ADP antiporter, mitochondrial inner membrane translocase complex YLR081W -2.929233 INESSENTIAL GAL2 galactose permease, galactose metabolism*, galactose transporter, plasma membrane YLR285W -2.943305 INESSENTIAL biological_process unknown, molecular_function unknown, YOL053W -2.947921 INESSENTIAL biological_process unknown, molecular_function unknown, YGL151W -2.962358 INESSENTIAL NUT1 negative regulator of HO endonuclease YAL007C -3.010390 INESSENTIAL ERP2 p24 protein involved in membrane trafficking,molecular_function unknown, YER109C -3.010821 INESSENTIAL FLO8 putative transcriptional activator of FLO1, pseudohyphal growth*, specific RNA polymerase II transcription factor, nucleus YML042W -3.014491 INESSENTIAL CAT2 Carnitine O-acetyltransferase, peroxisomal and mitochondrial, amino acid metabolism*, carnitine O-acetyltransferase, mitochondrion* YJR009C -3.018410 INESSENTIAL TDH2 glyceraldehyde 3-phosphate dehydrogenase, glycolysis*, glyceraldehyde 3-phosphate dehydrogenase (phosphorylating), cytosol* YHL007C -3.089008 INESSENTIAL STE20 serine threonine protein kinase, protein phosphorylation*, protein kinase, incipient bud site* YIL010W -3.154011 INESSENTIAL DOT5 involved in telomeric silencing, transcription, YMR232W -3.166728 INESSENTIAL FUS2 involved in cell fusion YMR241W -3.175478 INESSENTIAL YHM2 DNA-binding protein, mtDNA stabilizing protein, mitochondrial inner membrane protein with low homology to RIM2, biological_process unknown, YFR014C -3.181089 INESSENTIAL CMK1 Calmodulin-dependent protein kinase, protein phosphorylation*, calmodulin-dependent protein kinase I, cytoplasm YHR106W -3.219836 INESSENTIAL TRR2 mitochondrial thioredoxin reductase, oxidative stress response, thioredoxin reductase (NADPH), mitochondrion YAR030C -3.229750 INESSENTIAL biological_process unknown, molecular_function unknown, YIL009W -3.242416 INESSENTIAL FAA3 Acyl CoA synthase,long-chain-fatty-acid-CoA-ligase, YOR180C -3.244934 INESSENTIAL DCI1 Peroxisomal delta(3,5)-delta(2,4)-dienoyl-CoA isomerase, fatty acid beta-oxidation, dodecenoyl-CoA delta-isomerase, peroxisomal matrix YER101C -3.276856 INESSENTIAL AST2 involved in targeting of plasma membrane [H+]ATPase YCL006C -3.334862 INESSENTIAL YNL253W -3.355727 INESSENTIAL biological_process unknown, molecular_function unknown, YER027C -3.425064 INESSENTIAL GAL83 glucose repression protein, a component of the Snf1 complex YMR006C -3.436356 INESSENTIAL PLB2 lysophospholipase phospholipase B,lysophospholipase, YAL027W -3.466400 INESSENTIAL biological_process unknown, molecular_function unknown, YGL104C -3.494848 INESSENTIAL biological_process unknown, molecular_function unknown, YPL177C -3.505162 INESSENTIAL CUP9 putative DNA binding protein which shows similarity in homeobox domain to human proto-oncogene PBX1 YPR167C -3.548341 INESSENTIAL MET16 3'phosphoadenylylsulfate reductase, methionine metabolism*, phosphoadenylyl-sulfate reductase (thioredoxin), cellular_component unknown YER037W -3.554371 INESSENTIAL PHM8 biological_process unknown, molecular_function unknown, cellular_component unknown YAR020C -3.602837 INESSENTIAL PAU7 similar to Pau3, member of Pau1 family, biological_process unknown, molecular_function unknown, YIL059C -3.672083 INESSENTIAL biological_process unknown, molecular_function unknown, YNL145W -3.808269 INESSENTIAL MFA2 mating a-factor pheromone precursor, mating (sensu Saccharomyces), YNL058C -3.822869 INESSENTIAL biological_process unknown, molecular_function unknown, YDL085W -3.827254 INESSENTIAL biological_process unknown, molecular_function unknown, YJL130C -3.843253 INESSENTIAL URA2 carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase,aspartate carbamoyltransferase, YIL050W -3.852633 INESSENTIAL PCL7 PHO85 cyclin, cell cycle, cyclin, YMR041C -3.882667 INESSENTIAL biological_process unknown, molecular_function unknown, YPL087W -3.885880 INESSENTIAL YDC1 alkaline dihydroceramidase with minor reverse activity., sphingolipid metabolism, YMR010W -3.916744 INESSENTIAL biological_process unknown, molecular_function unknown, YOR240W -3.963258 INESSENTIAL YML005W -4.347559 INESSENTIAL biological_process unknown, molecular_function unknown,