YNL109W 404.656825 INESSENTIAL biological_process unknown, molecular_function unknown, YJL059W 280.083169 INESSENTIAL YHC3 Homolog of human CLN3, biological_process unknown, molecular_function unknown, YLR315W 278.367093 INESSENTIAL biological_process unknown, molecular_function unknown, YMR002W 271.295586 INESSENTIAL biological_process unknown, molecular_function unknown, YNL015W 266.279366 INESSENTIAL PBI2 Proteinase inhibitor that inhibits protease Prb1p (yscB), biological_process unknown, YJR113C 261.580695 INESSENTIAL RSM7 protein of the small subunit of the mitochondrial ribosome YDR457W 251.181121 INESSENTIAL TOM1 hect-domain-containing protein, containing kinase motifs; similar to Rsp5, polyubiquitylation*, ubiquitin--protein ligase, cellular_component unknown YBR038W 232.364484 IN CHS2 chitin synthase 2, cytokinesis*, chitin synthase, cytokinetic ring (sensu Saccharomyces) YDL045W-A 226.633469 INESSENTIAL MRP10 homologous to Yml37p, component of the 37 S subunit of mitochondrial ribosomes, protein biosynthesis, structural protein of ribosome, mitochondrial small ribosomal-subunit YHR038W 202.827831 INESSENTIAL FIL1 Putative mitochondrial ribosome recycling factor, protein biosynthesis, translation termination factor, mitochondrion YDL069C 202.531006 INESSENTIAL CBS1 translational activator of cytochrome b, protein biosynthesis, molecular_function unknown, mitochondrial inner membrane YJR104C 196.979250 INESSENTIAL SOD1 Cu, Zn superoxide dismutase,superoxide dismutase, YDR446W 196.816126 INESSENTIAL ECM11 (putative) involved in cell wall biogenesis,molecular_function unknown, YLL002W 194.869061 INESSENTIAL REM50 diepoxybutane and mitomycin C resistance,molecular_function unknown, YKR074W 192.555139 INESSENTIAL biological_process unknown, molecular_function unknown, YDR388W 189.106945 INESSENTIAL RVS167 (putative) cytoskeletal protein, endocytosis*, cytoskeletal protein binding protein, actin cortical patch (sensu Saccharomyces) YLR039C 185.849091 INESSENTIAL RIC1 involved in transcription of ribosomal protein genes and ribosomal RNA, transcription regulation from Pol II promoter*, molecular_function unknown, nucleus YOR019W 180.754069 INESSENTIAL biological_process unknown, molecular_function unknown, YJL063C 173.640693 INESSENTIAL MRPL8 Mitochondrial ribosomal protein MRPL8 (YmL8) (E. coli L17), protein biosynthesis*, structural protein of ribosome, mitochondrial large ribosomal-subunit YOR096W 169.405802 INESSENTIAL RPS7A Ribosomal protein S7A (rp30), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YHR100C 168.421182 INESSENTIAL biological_process unknown, molecular_function unknown, YMR256C 167.105582 INESSENTIAL COX7 subunit VII of cytochrome c oxidase,cytochrome-c oxidase, YBR173C 165.046042 INESSENTIAL UMP1 20S proteasome maturation factor YDL083C 156.956127 INESSENTIAL RPS16B Ribosomal protein S16B (rp61R), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YLL044W 150.374207 INESSENTIAL biological_process unknown, molecular_function unknown, YBR274W 148.890667 INESSENTIAL CHK1 Protein kinase Chk1, cell cycle, YJL056C 146.778416 INESSENTIAL ZAP1 Metalloregulatory protein involved in zinc-responsive transcriptional regulation, transcription regulation from Pol II promoter*, specific RNA polymerase II transcription factor, YHR066W 146.403516 INESSENTIAL SSF1 homologous to Ssf2p,molecular_function unknown, YDR433W 145.179059 INESSENTIAL KRE22 biological_process unknown, molecular_function unknown, YNL169C 144.339523 INESSENTIAL PSD1 Phosphatidylserine Decarboxylase 1,phosphatidylserine decarboxylase, YGR219W 143.090653 INESSENTIAL biological_process unknown, molecular_function unknown, YHR059W 139.728410 INESSENTIAL FYV4 biological_process unknown, molecular_function unknown, cellular_component unknown YNL271C 138.792434 INESSENTIAL BNI1 contains formin homology domains; homologous to BNR1 (BNI1 related protein), establishment of cell polarity (sensu Saccharomyces)*, cytoskeletal regulatory protein binding, actin cap (sensu Saccharomyces)* YCR028C-A 137.877656 INESSENTIAL RIM1 Single-stranded zinc finger DNA-binding protein YOL148C 137.829024 INESSENTIAL SPT20 transcription factor, member of the histone acetyltransferase SAGA complex SAGA complex YOR309C 136.852726 INESSENTIAL biological_process unknown, molecular_function unknown, YNL223W 136.348568 INESSENTIAL AUT2 Anchor protein. Mediates attachment of autophagosomes to microtubules., autophagy*, microtubule binding, microtubule associated protein YNL166C 135.096788 IN BNI5 bud neck protein, biological_process unknown, molecular_function unknown, YMR230W 134.827661 INESSENTIAL RPS10B Ribosomal protein S10B, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YPL161C 133.611228 INESSENTIAL BEM4 Involved in polarity establishment and bud emergence, establishment of cell polarity (sensu Saccharomyces)*, molecular_function unknown, cellular_component unknown YMR032W 133.114743 INESSENTIAL HOF1 SH3 domain containing-protein, cytokinesis, cytoskeletal protein binding protein, cytokinetic ring (sensu Saccharomyces) YHR049C-A 133.005963 INESSENTIAL biological_process unknown, molecular_function unknown, YNL208W 132.844133 INESSENTIAL biological_process unknown, molecular_function unknown, YJL102W 132.483405 INESSENTIAL MEF2 mitochondrial elongation factor G-like protein, protein synthesis elongation, translation elongation factor, mitochondrion YJL075C 132.225918 INESSENTIAL biological_process unknown, molecular_function unknown, YLR262C 130.749395 INESSENTIAL YPT6 highly homologous to the human GTPase, Rab6 YHR048W 127.080130 INESSENTIAL biological_process unknown, YDL116W 126.015306 INESSENTIAL NUP84 Protein with homology to mammalian Nup107p, mRNA-nucleus export*, structural protein, nuclear pore YHR008C 124.646499 INESSENTIAL SOD2 Manganese-containing superoxide dismutase,superoxide dismutase, YER068W 123.047648 INESSENTIAL MOT2 putative zinc finger protein, mating (sensu Saccharomyces), YHR091C 122.744849 INESSENTIAL MSR1 Arginyl-tRNA synthetase,arginine--tRNA ligase, YHR046C 122.208526 INESSENTIAL Inositol monophosphatase, biological_process unknown, molecular_function unknown, YJR063W 121.308402 INESSENTIAL RPA12 A12.2 subunit of RNA polymerase I, transcription from Pol I promoter, DNA-directed RNA polymerase I, DNA-directed RNA polymerase I YER077C 120.907755 INESSENTIAL biological_process unknown, molecular_function unknown, YPL024W 120.892330 INESSENTIAL NCE4 involved in cell separation YPR159W 120.809764 INESSENTIAL KRE6 potential beta-glucan synthase YKR020W 120.000278 INESSENTIAL biological_process unknown, molecular_function unknown, YJL183W 118.675406 INESSENTIAL MNN11 mannosyltransferase complex component, biological_process unknown, YCR020W-B 118.506432 INESSENTIAL HTL1 high-temperature lethal, biological_process unknown, molecular_function unknown, YLR261C 118.450702 INESSENTIAL biological_process unknown, molecular_function unknown, YNL139C 117.833879 INESSENTIAL RLR1 Involved in transcription, transcription,nucleus YHR183W 117.595258 INESSENTIAL GND1 Phosphogluconate Dehydrogenase (Decarboxylating),phosphogluconate dehydrogenase (decarboxylating), YPL045W 116.501946 INESSENTIAL VPS16 Vacuolar sorting protein, protein-vacuolar targeting*, molecular_function unknown, vacuolar membrane* YIL093C 116.419479 INESSENTIAL RSM25 protein of the small subunit of the mitochondrial ribosome YDR245W 116.094767 INESSENTIAL MNN10 galactosyltransferase, actin filament organization*, alpha-1,6-mannosyltransferase, mannosyltransferase complex YNL234W 115.932739 INESSENTIAL biological_process unknown, molecular_function unknown, YDL005C 115.651202 INESSENTIAL MED2 Stoichiometric member of mediator complex, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YGL195W 115.371363 INESSENTIAL GCN1 translational activator of GCN4 through activation of GCN2 in response to starvation YLR046C 113.987690 INESSENTIAL biological_process unknown, molecular_function unknown, YGL206C 113.766288 INESSENTIAL CHC1 presumed vesicle coat protein YGR118W 113.565729 INESSENTIAL RPS23A Ribosomal protein S23A (S28A) (rp37) (YS14), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YMR066W 112.962945 INESSENTIAL SOV1 (putative) involved in respiration,molecular_function unknown, YDR079W 112.674451 INESSENTIAL PET100 cytochrome c oxidase-specific assembly factor, cytochrome c oxidase biogenesis, molecular_function unknown, cellular_component unknown YAL016W 111.954400 INESSENTIAL TPD3 protein phosphatase 2A regulatory subunit A, protein biosynthesis*, protein phosphatase type 2A, protein phosphatase type 2A YLR244C 111.301013 INESSENTIAL MAP1 methionine aminopeptidase,methionyl aminopeptidase, YNL228W 110.530580 INESSENTIAL biological_process unknown, molecular_function unknown, YNL059C 109.872142 INESSENTIAL ARP5 Actin-related protein, biological_process unknown, molecular_function unknown, cell YPL188W 109.322477 INESSENTIAL POS5 involved in oxidative stress, biological_process unknown, molecular_function unknown, YPL268W 109.247379 INESSENTIAL PLC1 phosphoinositide-specific phospholipase C, pseudohyphal growth*, 1-phosphatidylinositol-4,5-biphosphate phosphodiesterase, cellular_component unknown YLR193C 108.839186 INESSENTIAL biological_process unknown, molecular_function unknown, YBR279W 107.921717 INESSENTIAL PAF1 RNA polymerase II-associated protein, transcription, YBR282W 106.944286 INESSENTIAL MRPL27 Mitochondrial ribosomal protein MRPL27 (YmL27), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YNL133C 106.225113 INESSENTIAL FYV6 biological_process unknown, molecular_function unknown, cellular_component unknown YJL006C 105.821770 INESSENTIAL CTK2 cyclin-like protein, protein phosphorylation*, cyclin, YJL188C 105.621749 INESSENTIAL BUD19 biological_process unknown, molecular_function unknown, YKL139W 104.799111 INESSENTIAL CTK1 alpha subunit of the kinase which phosphorylates the RNA polymerase largest subunit CTD (carboxyl-terminal domain), protein phosphorylation*, protein kinase, YNL029C 104.019119 INESSENTIAL KTR5 Putative mannosyltransferase, cell wall organization and biogenesis*, mannosyltransferase, Golgi apparatus YLR295C 103.217551 INESSENTIAL ATP14 ATP synthase subunit h, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, F0 sector YDL198C 102.996325 INESSENTIAL YHM1 (putative) mitochondrial carrier protein, transport, YMR158W 102.781612 INESSENTIAL biological_process unknown, molecular_function unknown, YPL129W 102.243782 INESSENTIAL ANC1 transcription initiation factor TFIIF small subunit, transcription initiation from Pol II promoter*, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex* YNL008C 101.644520 INESSENTIAL biological_process unknown, molecular_function unknown, YNL164C 101.389104 INESSENTIAL biological_process unknown, molecular_function unknown, YFL018C 101.084690 INESSENTIAL LPD1 dihydrolipoamide dehydrogenase precursor (mature protein is the E3 component of alpha-ketoacid dehydrogenase complexes), serine biosynthesis*, dihydrolipoamide dehydrogenase, mitochondrial matrix* YLL006W 100.806201 INESSENTIAL MMM1 mitochondrial outer membrane protein, mitochondrion inheritance*, molecular_function unknown, mitochondrial outer membrane YGR165W 99.193683 INESSENTIAL biological_process unknown, molecular_function unknown, YNR047W 98.853551 INESSENTIAL biological_process unknown, molecular_function unknown, YNR010W 98.650094 INESSENTIAL CSE2 Component of RNA polymerase II mediator subcomplex, transcription from Pol II promoter*, RNA polymerase II transcription mediator, mediator complex YJL092W 98.380621 INESSENTIAL HPR5 DNA helicase, DNA repair, DNA helicase, nucleus YDL075W 98.155536 INESSENTIAL RPL31A Ribosomal protein L31A (L34A) (YL28), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YMR166C 97.766279 INESSENTIAL biological_process unknown, molecular_function unknown, YMR021C 97.262707 INESSENTIAL MAC1 metal-binding transcriptional activator,transcription factor, YJL140W 96.345984 INESSENTIAL RPB4 fourth-largest subunit of RNA polymerase II, transcription from Pol II promoter, DNA-directed RNA polymerase II, DNA-directed RNA polymerase II, core YHR050W 96.263690 INESSENTIAL SMF2 localized to mitochondrial membrane, manganese ion transport, manganese ion transporter, mitochondrial membrane YFL016C 95.753224 INESSENTIAL MDJ1 DnaJ homolog involved in mitochondrial biogenesis and protein folding, protein folding*, heat shock protein, mitochondrial inner membrane YPL029W 94.758593 INESSENTIAL SUV3 putative ATP-dependent helicase,RNA helicase, YGL200C 94.205442 INESSENTIAL EMP24 type I transmemebrane protein, component of COPII-coated, ER-derived transport vesicles YHR078W 93.972021 INESSENTIAL biological_process unknown, molecular_function unknown, YOL076W 93.529784 INESSENTIAL MDM20 involved in mitochondrial inheritance and actin assembly, cytoskeleton organization and biogenesis*, actin binding, intracellular YHR182W 92.947752 INESSENTIAL biological_process unknown, molecular_function unknown, YIL128W 91.827064 INESSENTIAL MET18 regulator of TFIIH, transcription from Pol II promoter*, RNA polymerase II transcription factor, nucleoplasm YOL086C 91.284504 INESSENTIAL ADH1 Alcohol dehydrogenase,acylglycerone-phosphate reductase, YLR333C 91.240331 INESSENTIAL RPS25B Ribosomal protein S25B (S31B) (rp45) (YS23), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDR129C 91.211516 INESSENTIAL SAC6 fibrim homolog (actin-filament bundling protein), endocytosis*, actin cross-linking, actin cortical patch (sensu Saccharomyces)* YGR159C 91.017805 INESSENTIAL NSR1 nuclear localization sequence binding protein, rRNA processing*, RNA binding, nucleolus YHR079C 90.806941 INESSENTIAL IRE1 Ire1p is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities, myo-inositol metabolism*, protein serine/threonine kinase*, endoplasmic reticulum membrane* YNL081C 90.623674 INESSENTIAL biological_process unknown, molecular_function unknown, YPL031C 90.307273 INESSENTIAL PHO85 cyclin-dependent protein kinase, protein phosphorylation*, cyclin-dependent protein kinase*, YNL284C 89.960466 INESSENTIAL MRPL10 Mitochondrial ribosomal protein MRPL10 (YmL10), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YJL003W 89.217562 INESSENTIAL biological_process unknown, molecular_function unknown, YKL003C 89.031607 INESSENTIAL MRP17 Mitochondrial ribosomal protein MRP17, protein biosynthesis, structural protein of ribosome, mitochondrial small ribosomal-subunit YNL005C 87.878865 INESSENTIAL MRP7 Mitochondrial ribosomal protein MRP7 (YmL2) (E. coli L27), protein biosynthesis, structural protein of ribosome*, mitochondrial large ribosomal-subunit YER074W 87.502780 INESSENTIAL RPS24A 40S ribosomal protein S24A, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDR138W 87.176959 INESSENTIAL HPR1 involved in mitosis, recombination; similar to TOP1 across 2 regions, DNA recombination, molecular_function unknown, nucleus YGR085C 87.139606 INESSENTIAL RPL11B 60S ribosomal protein L11B (L16B) (rp39B) (YL22), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YDR322W 87.058619 INESSENTIAL MRPL35 Mitochondrial ribosomal protein MRPL35 (YmL35), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YDL042C 86.867441 INESSENTIAL SIR2 regulator of silencing at HML, HMR, telomeres, and rDNA, chromatin silencing at HML and HMR (sensu Saccharomyces)*, histone deacetylase, nucleolus* YNL021W 86.624729 INESSENTIAL HDA1 histone deacetylase, shares sequence similarity with Rpd3p, Hos1p, Hos2p, and Hos3p, chromatin architecture*, histone deacetylase, histone deacetylase complex YPL086C 86.248827 INESSENTIAL ELP3 RNA polymerase II-associated Histone acetyltransferase YGR020C 85.859035 INESSENTIAL VMA7 vacuolar ATPase V1 domain subunit F (14 kDa), vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V1 domain YLR318W 84.540151 INESSENTIAL EST2 103 kD basic protein, catalytic subunit of telomerase YGL174W 84.467065 INESSENTIAL BUD13 biological_process unknown, molecular_function unknown, YDR136C 84.310160 INESSENTIAL biological_process unknown, molecular_function unknown, YDR432W 83.685571 INESSENTIAL NPL3 nuclear shuttling protein with an RNA recognition motif YHR080C 83.612326 INESSENTIAL biological_process unknown, molecular_function unknown, YOR073W 83.390375 INESSENTIAL biological_process unknown, molecular_function unknown, YLR425W 83.253711 INESSENTIAL TUS1 1307 AA, hydrophilic protein., biological_process unknown, molecular_function unknown, YDR027C 83.080920 INESSENTIAL LUV1 involved in vacuole biogenesis,molecular_function unknown, YIL134W 82.997053 INESSENTIAL FLX1 mitochondrial inner membrane carrier protein for FAD, mitochondrial transport, flavin adenine dinucleotide transporter, mitochondrion YOL023W 82.992115 INESSENTIAL IFM1 mitochondrial initiation factor 2, protein synthesis initiation, translation initiation factor, mitochondrion YPL069C 82.989285 INESSENTIAL BTS1 geranylgeranyl diphosphate synthase YKL057C 82.915595 INESSENTIAL NUP120 100-kDa protein (predicted molecular weight is 120 kDa) with two leucine zipper motifs, coiled-coil region, and some homology to Nup133p, mRNA-nucleus export*, structural protein, nuclear pore YLR235C 82.706413 INESSENTIAL biological_process unknown, molecular_function unknown, YEL044W 82.555447 INESSENTIAL biological_process unknown, molecular_function unknown, YKR082W 82.530175 INESSENTIAL NUP133 nuclear pore protein, mRNA-nucleus export*, structural protein, nuclear pore YIL009C-A 81.979325 INESSENTIAL EST3 181aa protein - 20.5 kD,molecular_function unknown, YLR048W 81.499824 INESSENTIAL RPS0B Ribosomal protein S0B, protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YLR304C 81.215096 INESSENTIAL ACO1 Aconitase, mitochondrial, tricarboxylic acid cycle*, aconitate hydratase, cytosol* YOR106W 81.041343 INESSENTIAL VAM3 member of the syntaxin family of proteins; predicted C-terminal TMD, non-selective vesicle fusion*, t-SNARE, vacuolar membrane YOR293W 80.839780 INESSENTIAL RPS10A Ribosomal protein S10A, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YLR138W 80.760726 INESSENTIAL NHA1 Putative Na+ H+ antiporter YPR139C 80.385019 INESSENTIAL biological_process unknown, molecular_function unknown, YGL170C 80.175478 INESSENTIAL SPO74 biological_process unknown, molecular_function unknown, YKL055C 80.092479 INESSENTIAL OAR1 3-oxoacyl-[acyl-carrier-protein] reductase, respiration, YPL274W 79.940876 INESSENTIAL SAM3 High affinity S-adenosylMethionine Permease, sulfur amino acid transport, amino acid-polyamine transporter, cellular_component unknown YJL189W 79.586169 INESSENTIAL RPL39 Ribosomal protein L39 (L46) (YL40), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YBL100C 79.532981 INESSENTIAL biological_process unknown, molecular_function unknown, YML115C 79.475311 INESSENTIAL VAN1 mannosyltransferase,mannosyltransferase, YLR062C 79.445200 INESSENTIAL BUD28 biological_process unknown, molecular_function unknown, cellular_component unknown YDR210W 79.100084 INESSENTIAL biological_process unknown, molecular_function unknown, YPR008W 78.997889 INESSENTIAL biological_process unknown, molecular_function unknown, YER139C 78.923062 INESSENTIAL biological_process unknown, molecular_function unknown, YDR532C 78.801672 INESSENTIAL KRE28 biological_process unknown, molecular_function unknown, YGL033W 78.783592 INESSENTIAL HOP2 Meiosis-specific gene required for the pairing of homologous chromosomes,molecular_function unknown, YLR233C 78.333954 INESSENTIAL EST1 involved in telomere length regulation YPL047W 78.264448 INESSENTIAL biological_process unknown, molecular_function unknown, YPL090C 78.254060 INESSENTIAL RPS6A Ribosomal protein S6A (S10A) (rp9) (YS4), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YBL090W 78.248083 INESSENTIAL MRP21 Component of the small subunit of mitochondrial ribosomes, protein biosynthesis*, structural protein of ribosome, mitochondrial small ribosomal-subunit YKL079W 78.149231 INESSENTIAL SMY1 kinesin heavy chain homolog, exocytosis, motor, bud tip* YHR073W 77.818372 INESSENTIAL OSH3 Oxysterol-binding protein, biological_process unknown, molecular_function unknown, YKR044W 77.029917 INESSENTIAL biological_process unknown, molecular_function unknown, YOR258W 76.674947 INESSENTIAL biological_process unknown, molecular_function unknown, YFR001W 76.174150 INESSENTIAL LOC1 Double-stranded RNA-binding protein YJL150W 76.137698 INESSENTIAL biological_process unknown, molecular_function unknown, YBR076W 75.985119 INESSENTIAL ECM8 involved in cell wall biogenesis,molecular_function unknown, YBR191W 75.888578 INESSENTIAL RPL21A Ribosomal protein L21A, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YHR147C 75.866637 INESSENTIAL MRPL6 Mitochondrial ribosomal protein MRPL6 (YmL6), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YMR143W 75.819036 INESSENTIAL RPS16A Ribosomal protein S16A (rp61R), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YKR001C 75.745213 INESSENTIAL VPS1 putative GTP-binding protein; similar to mammalian Mx proteins, protein-vacuolar targeting*, GTPase, membrane fraction YPR043W 75.744797 INESSENTIAL RPL43A Ribosomal protein L43A, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YCR047C 75.736286 INESSENTIAL BUD23 Protein carboxyl methylase, biological_process unknown, molecular_function unknown, YNL246W 75.392268 INESSENTIAL biological_process unknown, molecular_function unknown, YPR131C 75.323578 INESSENTIAL NAT3 N-terminal acetyltransferase YDR418W 75.258463 INESSENTIAL RPL12B Ribosomal protein L12B (L15B) (YL23), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YDR092W 75.199071 INESSENTIAL UBC13 ubiquitin-conjugating enzyme, polyubiquitylation*, ubiquitin conjugating enzyme, nucleus YLR420W 75.093439 INESSENTIAL URA4 dihydrooratase,dihydroorotase, YDL090C 75.029523 INESSENTIAL RAM1 beta subunit of farnesyltransferase YGL246C 74.895971 INESSENTIAL RAI1 biological_process unknown, molecular_function unknown, YIL100W 74.563536 INESSENTIAL biological_process unknown, molecular_function unknown, YLR067C 74.395671 INESSENTIAL PET309 involved in COX1 mRNA stability, protein biosynthesis*, molecular_function unknown, mitochondrial inner membrane YPR077C 74.333641 INESSENTIAL biological_process unknown, molecular_function unknown, YLR388W 74.176682 INESSENTIAL RPS29A Ribosomal protein S29A (S36A) (YS29), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YML110C 74.167731 INESSENTIAL COQ5 Putative mitochondrial C-methyltransferase, ubiquinone metabolism,mitochondrion YBL093C 73.341903 INESSENTIAL ROX3 RNA polymerase II holoenzyme mediator subunit, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YLR061W 73.254846 INESSENTIAL RPL22A Ribosomal protein L22A (L1c) (rp4) (YL31), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YBL033C 73.219675 INESSENTIAL RIB1 GTP cyclohydrolase II,GTP cyclohydrolase II, YKL169C 73.160078 INESSENTIAL biological_process unknown, molecular_function unknown, YMR224C 73.026455 INESSENTIAL MRE11 localizes to discrete sites in rad50s mutants. Mre11p, Rad50p, Mer2p and Xrs2p function in a complex by immunoprecipitation and two-hybrid analyses; mutations in these genes have similar phenotypes. mRNA is induced in meiosis, DNA repair*, endonuclease, nucleus YPL271W 72.944972 INESSENTIAL ATP15 nuclear gene for ATP synthase epsilon subunit, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, central stalk YLR049C 72.862943 INESSENTIAL biological_process unknown, molecular_function unknown, YJL136C 72.619731 INESSENTIAL RPS21B Ribosomal protein S21B (S26B) (YS25), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YFL036W 72.148402 INESSENTIAL RPO41 mitohcondrial RNA polymerase, mitochondrial genome maintenance*, DNA-directed RNA polymerase, mitochondrial matrix YLL033W 72.077801 INESSENTIAL biological_process unknown, molecular_function unknown, YGL218W 71.043084 INESSENTIAL biological_process unknown, molecular_function unknown, YKL113C 70.999699 INESSENTIAL RAD27 42 kDa 5' to 3' exonuclease required for Okazaki fragment processing, DNA repair, YCR066W 70.832140 INESSENTIAL RAD18 Zn finger protein, putative ATPase YHR092C 70.828343 INESSENTIAL HXT4 High-affinity glucose transporter, transport, YLR327C 69.926576 INESSENTIAL biological_process unknown, molecular_function unknown, YLR264W 69.779314 INESSENTIAL RPS28B Ribosomal protein S28B (S33B) (YS27), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YBR251W 69.654838 INESSENTIAL MRPS5 Probable mitochondrial ribosomal protein S5, protein biosynthesis, structural protein of ribosome, mitochondrial ribosome YBR168W 69.313525 INESSENTIAL biological_process unknown, molecular_function unknown, YGL143C 69.181918 INESSENTIAL MRF1 Mitochondrial polypeptide chain release factor, protein biosynthesis*, translation release factor, mitochondrion YER050C 69.086172 INESSENTIAL RSM18 protein of the small subunit of the mitochondrial ribosome YHR039C-B 68.790271 INESSENTIAL YOR078W 68.589336 INESSENTIAL BUD21 BUD site selection, biological_process unknown, molecular_function unknown, YBR277C 68.384090 INESSENTIAL biological_process unknown, molecular_function unknown, YCL026C 68.318543 INESSENTIAL FRM2 involved in fatty acid signaling,molecular_function unknown, YDR175C 67.908488 INESSENTIAL RSM24 protein of the small subunit of the mitochondrial ribosome YDR226W 67.740697 INESSENTIAL ADK1 adenylate kinase,adenylate kinase, YCR044C 67.667552 INESSENTIAL PER1 Protein Processing in the ER,molecular_function unknown, YBR127C 66.983297 INESSENTIAL VMA2 vacuolar ATPase V1 domain subunit B (60 kDa), vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V1 domain YDL047W 66.888208 INESSENTIAL SIT4 type 2A related protein phosphatase, G1/S transition of mitotic cell cycle, protein serine/threonine phosphatase, cytoplasm YJL176C 66.742078 INESSENTIAL SWI3 transcription factor, chromatin modeling, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex YBL058W 66.445623 INESSENTIAL SHP1 putative regulatory subunit for Glc7p, a phosphatase required for glucose repression, sporulation (sensu Saccharomyces)*, molecular_function unknown, cellular_component unknown YBR166C 66.388168 INESSENTIAL TYR1 Prephenate dehydrogenase (NADP+),prephenate dehydrogenase (NADP+), YDR025W 65.910102 INESSENTIAL RPS11A Ribosomal protein S11A (S18A) (rp41A) (YS12), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YNL280C 65.849153 INESSENTIAL ERG24 sterol C-14 reductase, ergosterol biosynthesis, C-14 sterol reductase, endoplasmic reticulum YGR262C 65.600058 INESSENTIAL BUD32 biological_process unknown, molecular_function unknown, cellular_component unknown YNL003C 65.304515 INESSENTIAL PET8 mitochondrial carrier protein family, biological_process unknown, molecular_function unknown, cellular_component unknown YML128C 65.237722 INESSENTIAL MSC1 biological_process unknown, molecular_function unknown, cellular_component unknown YGR104C 65.208645 INESSENTIAL SRB5 subunit of RNA polymerase II holoenzyme mediator complex, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YHR011W 65.086873 INESSENTIAL DIA4 Seryl-tRNA synthetase, pseudohyphal growth*, serine--tRNA ligase, cellular_component unknown YLR052W 65.002570 INESSENTIAL IES3 biological_process unknown, molecular_function unknown, YDL216C 64.689603 INESSENTIAL RRI1 biological_process unknown, molecular_function unknown, cellular_component unknown YDL044C 63.897003 INESSENTIAL MTF2 involved in mRNA splicing, mRNA processing, RNA binding, mitochondrion YLR139C 63.845928 INESSENTIAL SLS1 73 kDa mitochondrial integral membrane protein YPL089C 63.741343 INESSENTIAL RLM1 serum response factor-like protein, signal transduction, transcription factor, nucleus YDR195W 63.578554 INESSENTIAL REF2 RNA-binding protein, involved in mRNA processing,molecular_function unknown, YOR026W 63.565255 INESSENTIAL BUB3 cell cycle checkpoint protein, mitotic spindle checkpoint, molecular_function unknown, cellular_component unknown YLR234W 63.326526 INESSENTIAL TOP3 DNA Topoisomerase III, meiotic recombination*, DNA topoisomerase I, YDR442W 62.598695 INESSENTIAL biological_process unknown, molecular_function unknown, YHR168W 62.295756 INESSENTIAL GTP-binding protein, biological_process unknown, molecular_function unknown, YBR266C 61.949244 INESSENTIAL probable membrane protein, biological_process unknown, molecular_function unknown, YDL081C 61.925473 INESSENTIAL RPP1A Acidic ribosomal protein P1A (YP1alpha) (A1), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YJL088W 61.820343 INESSENTIAL ARG3 Ornithine carbamoyltransferase, arginine biosynthesis*, ornithine carbamoyltransferase, cytosol YEL045C 61.260743 INESSENTIAL biological_process unknown, molecular_function unknown, YPR036W 61.132832 INESSENTIAL VMA13 vacuolar ATPase V1 domain subunit H (54 kDa), vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V1 domain YKR050W 61.090898 INESSENTIAL TRK2 membrane protein; low affinity potassium transport, transport, YJL096W 60.986906 INESSENTIAL MRPL49 mitochondrial ribosomal protein of the large subunit, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YPR114W 60.960709 INESSENTIAL biological_process unknown, molecular_function unknown, YOR227W 60.586352 INESSENTIAL biological_process unknown, molecular_function unknown, YBR171W 60.580915 INESSENTIAL SEC66 glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex required for translocation of presecretory proteins, SRP-dependent, co-translational membrane targeting, translocation*, signal recognition particle receptor, signal recognition particle receptor YAL047C 60.443824 INESSENTIAL SPC72 component of spindle pole bodies, microtubule nucleation*, structural protein of cytoskeleton, outer plaque of spindle pole body YCL029C 60.321859 INESSENTIAL BIK1 Microtubule-binding protein, mitotic anaphase B*, microtubule binding, spindle pole body* YDR089W 60.203765 INESSENTIAL biological_process unknown, molecular_function unknown, YPR163C 59.965331 INESSENTIAL TIF3 Translation initiation factor eIF-4B, protein synthesis initiation, translation initiation factor, ribosome YDR024W 59.438132 INESSENTIAL FYV1 biological_process unknown, molecular_function unknown, cellular_component unknown YER095W 59.281715 INESSENTIAL RAD51 RecA homolog; Rad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsis (independently of ZIP1 and DMC1), and interacts with Rad52p and Rad55p; human Rad51p homolog interacts with Brca2 protein which has been implicated in causing breast cancer,recombinase, YNL138W 58.850500 INESSENTIAL SRV2 70-kDa adenylyl cyclase-associated protein, cytoskeleton organization and biogenesis*, cytoskeletal protein binding protein*, actin cortical patch (sensu Saccharomyces) YMR091C 58.784568 INESSENTIAL NPL6 involved in nuclear protein targeting,molecular_function unknown, YCR063W 58.615638 INESSENTIAL BUD31 G10-like protein, biological_process unknown, molecular_function unknown, cellular_component unknown YLR074C 58.528526 INESSENTIAL BUD20 BUD site selection, biological_process unknown, molecular_function unknown, cellular_component unknown YMR142C 58.443127 INESSENTIAL RPL13B Ribosomal protein L13B, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YNL302C 58.032243 INESSENTIAL RPS19B Ribosomal protein S19B (rp55B) (S16aB) (YS16B), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YLR251W 58.029442 INESSENTIAL biological_process unknown, molecular_function unknown, YMR267W 58.012528 INESSENTIAL PPA2 mitochondrial inorganic pyrophosphatase, respiration, inorganic diphosphatase, mitochondrion YLR402W 57.937919 INESSENTIAL biological_process unknown, molecular_function unknown, YLR068W 57.936971 INESSENTIAL FYV7 biological_process unknown, molecular_function unknown, cellular_component unknown YDR296W 57.900519 INESSENTIAL MHR1 Involved in mitochondrial homologous DNA recombination,molecular_function unknown, YER070W 57.758645 INESSENTIAL RNR1 ribonucleotide reductase, DNA replication, ribonucleoside-diphosphate reductase, cytosol YFL023W 57.620389 INESSENTIAL FYV11 biological_process unknown, molecular_function unknown, cellular_component unknown YGR180C 57.296592 INESSENTIAL RNR4 Ribonucleotide Reductase, DNA replication, ribonucleoside-diphosphate reductase, nucleus YDR300C 57.262031 INESSENTIAL PRO1 gamma-glutamyl kinase,glutamate 5-kinase, YCR091W 56.661864 INESSENTIAL KIN82 Putative serine threonine protein kinase most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily, biological_process unknown, protein kinase, YML024W 56.363084 INESSENTIAL RPS17A Ribosomal protein S17A (rp51A), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDL006W 55.852955 INESSENTIAL PTC1 serine-threonine protein phosphatase, tRNA splicing*, protein phosphatase type 2C, cytosol YCL034W 55.845880 INESSENTIAL biological_process unknown, molecular_function unknown, YOR054C 55.817139 INESSENTIAL biological_process unknown, molecular_function unknown, YOL100W 55.172394 INESSENTIAL PKH2 Ser Thr protein kinase, biological_process unknown, YGL129C 54.889169 INESSENTIAL RSM23 protein of the small subunit of the mitochondrial ribosome YFR019W 54.126667 INESSENTIAL FAB1 type II PI(4)P5-kinase (PIP4,5 kinase) similar to human PIP5K-II, vacuole organization and biogenesis, 1-phosphatidylinositol-3-phosphate 5-kinase, vacuolar membrane YLR342W 54.092525 INESSENTIAL FKS1 1,3-beta-D-glucan synthase, cell wall organization and biogenesis*, 1,3-beta-glucan synthase, actin cap (sensu Saccharomyces)* YDR470C 53.969216 INESSENTIAL UGO1 mitochondrial fusion, molecular_function unknownmitochondrial outer membrane YOL050C 53.940548 INESSENTIAL biological_process unknown, molecular_function unknown, YDR507C 53.808083 INESSENTIAL GIN4 putative serine threonine kinase, protein phosphorylation*, protein kinase, bud neck YMR193W 53.793916 INESSENTIAL MRPL24 Mitochondrial ribosomal protein MRPL24 (YmL24), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YGR036C 53.751448 INESSENTIAL CAX4 CAX4p contains 3 short stretches of amino acids that are characteristic for a wide variety of phosphatases, including lipid phosphatases and a protein phosphatase.,molecular_function unknown, YGL211W 53.699711 INESSENTIAL biological_process unknown, molecular_function unknown, YJR125C 53.475783 INESSENTIAL ENT3 Ent3p, actin filament organization*, cytoskeletal adaptor, actin cortical patch (sensu Saccharomyces) YGL036W 53.427493 INESSENTIAL MTC2 Mtf1 Two Hybrid Clone 2, biological_process unknown, molecular_function unknown, YDR382W 53.350017 INESSENTIAL RPP2B Ribosomal protein P2B (YP2beta) (L45), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YNL215W 53.292892 INESSENTIAL IES2 biological_process unknown, molecular_function unknown, YMR098C 53.211200 INESSENTIAL biological_process unknown, molecular_function unknown, YNL235C 53.185500 INESSENTIAL biological_process unknown, molecular_function unknown, YEL054C 53.148870 INESSENTIAL RPL12A Ribosomal protein L12A (L15A) (YL23), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YGL220W 53.057360 INESSENTIAL biological_process unknown, molecular_function unknown, YNR022C 52.154527 INESSENTIAL biological_process unknown, molecular_function unknown, YOR270C 51.781289 INESSENTIAL VPH1 vacuolar ATPase V0 domain subunit a (100 kDa), vacuolar acidification*, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V0 domain YLR044C 51.602105 INESSENTIAL PDC1 pyruvate decarboxylase,alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, YIL133C 51.588082 INESSENTIAL RPL16A Ribosomal protein L16A (L21A) (rp22) (YL15), protein biosynthesis, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YER017C 51.483208 INESSENTIAL AFG3 ATP-dependent metalloprotease, protein complex assembly*, adenosinetriphosphatase*, mitochondrial inner membrane YKR085C 51.404728 INESSENTIAL MRPL20 22.3 kDa mitochondrial ribosomal large subunit protein YmL20; homologous to L17 of E. coli, protein biosynthesis*, structural protein of ribosome, mitochondrial large ribosomal-subunit YGL070C 51.059916 INESSENTIAL RPB9 RNA polymerase II subunit, transcription from Pol II promoter, DNA-directed RNA polymerase II, DNA-directed RNA polymerase II, core YOR331C 51.047936 INESSENTIAL biological_process unknown, molecular_function unknown, YBR126C 51.031911 INESSENTIAL TPS1 56 kD synthase subunit of trehalose-6-phosphate synthase phosphatase complex, stress response*, alpha,alpha-trehalose-phosphate synthase (UDP-forming), alpha,alpha-trehalose-phosphate synthase (UDP-forming) YML094W 50.540962 INESSENTIAL GIM5 bovine prefoldin subunit 5 homolog (putative), protein folding, YNL040W 50.290088 INESSENTIAL biological_process unknown, molecular_function unknown, YPL125W 50.263731 INESSENTIAL KAP120 karyopherin YLR441C 50.219399 INESSENTIAL RPS1A Ribosomal protein S1A (rp10A), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YMR089C 50.020081 INESSENTIAL YTA12 mitochondrial membrane ATPase of the CDC48 PAS1 SEC18 (AAA) family, protein complex assembly*, adenosinetriphosphatase*, mitochondrial inner membrane YDR332W 49.965755 INESSENTIAL biological_process unknown, molecular_function unknown, YOL008W 49.895155 INESSENTIAL biological_process unknown, molecular_function unknown, YDL077C 49.833943 INESSENTIAL VAM6 involved in vacuolar morphogenesis,vacuolar carboxypeptidase Y, YMR198W 49.798186 INESSENTIAL CIK1 spindle pole body associated protein, mitotic chromosome segregation*, microtubule motor, cytoplasmic microtubule* YLR200W 49.663488 INESSENTIAL YKE2 Polypeptide 6 of a Yeast Non-native Actin Binding Complex, homolog of a component of the bovine NABC complex YHL025W 49.640267 INESSENTIAL SNF6 subunit of the chromatin remodeling Snf Swi complex, chromatin modeling, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex YAL013W 49.590069 INESSENTIAL DEP1 regulation of phospholipid metabolism, phospholipid metabolism, YLL007C 49.323516 INESSENTIAL biological_process unknown, molecular_function unknown, YHL033C 49.262867 INESSENTIAL RPL8A Ribosomal protein L8A (rp6) (YL5) (L4A), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YDR176W 49.257145 INESSENTIAL NGG1 transcription factor; genetic and mutant analyses suggest that Ngg1p (Ada3p) is part of two transcriptional adaptor HAT (histone acetyltransferase complexes, the 0.8 MD ADA complex and the 1.8 MD SAGA complex SAGA complex YLR242C 49.200301 INESSENTIAL ARV1 similar to Nup120p and C.elegans R05H5.5 protein and Nup120p, biological_process unknown, molecular_function unknown, YDR450W 49.079629 INESSENTIAL RPS18A Ribosomal protein S18A, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YGL009C 49.060970 INESSENTIAL LEU1 isopropylmalate isomerase,3-isopropylmalate dehydratase, YPL180W 49.054531 INESSENTIAL biological_process unknown, molecular_function unknown, YBL038W 49.006728 INESSENTIAL MRPL16 Mitochondrial ribosomal protein MRPL16, protein biosynthesis, structural protein of ribosome*, mitochondrial large ribosomal-subunit YLR270W 48.287979 INESSENTIAL biological_process unknown, molecular_function unknown, YDR241W 48.255353 INESSENTIAL BUD26 BUD site selection, biological_process unknown, molecular_function unknown, YDR298C 48.216478 INESSENTIAL ATP5 ATP synthase subunit 5; oligomycin sensitivity-conferring protein, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, stator stalk YGR285C 48.170331 INESSENTIAL ZUO1 Zuotin, putative Z-DNA binding protein, protein folding, chaperone, cytosol* YKL054C 47.992965 INESSENTIAL VID31 vacuole import and degradation,molecular_function unknown, YGR062C 47.804065 INESSENTIAL COX18 required for mitochondrial cytochrome oxidase activity, cytochrome c oxidase biogenesis, molecular_function unknown, mitochondrial membrane YFR036W 47.745137 INESSENTIAL CDC26 cell division control protein, ubiquitin-dependent protein degradation*, ubiquitin--protein ligase*, anaphase-promoting complex YBR201W 47.739454 INESSENTIAL DER1 involved in degradation in the ER,molecular_function unknown, YEL029C 47.156855 INESSENTIAL BUD16 biological_process unknown, molecular_function unknown, YEL040W 47.096403 INESSENTIAL UTR2 biological_process unknown, molecular_function unknown, YJL184W 47.090014 INESSENTIAL biological_process unknown, molecular_function unknown, YLR043C 46.939338 INESSENTIAL TRX1 thioredoxin, oxidative stress response*, thioredoxin, cytosol YJR034W 46.736227 INESSENTIAL PET191 involved in cytochrome c oxidase assembly, cytochrome c oxidase biogenesis, molecular_function unknown, mitochondrial inner membrane YGL219C 46.720141 INESSENTIAL biological_process unknown, molecular_function unknown, cellular_component unknown YDL068W 46.598374 INESSENTIAL biological_process unknown, molecular_function unknown, YGL005C 46.501986 INESSENTIAL biological_process unknown, molecular_function unknown, YPL106C 46.401480 INESSENTIAL SSE1 HSP70 family member, highly homologous to Ssa1p and Sse2p, protein folding, cochaperone, cytoplasm YOR209C 46.359991 INESSENTIAL NPT1 nicotinate phosphoribosyl transferase (putative),nicotinate phosphoribosyltransferase, YDR417C 46.340370 INESSENTIAL biological_process unknown, molecular_function unknown, YFL001W 46.281518 INESSENTIAL DEG1 Depressed growth-rate protein, RNA processing, pseudouridylate synthase, nucleus* YDR337W 46.051391 INESSENTIAL MRPS28 Mitochondrial ribosomal protein MRPS28 (E. coli S15), protein biosynthesis*, structural protein of ribosome*, mitochondrial small ribosomal-subunit YPL104W 46.044470 INESSENTIAL MSD1 Aspartyl-tRNA synthetase, mitochondrial, protein biosynthesis, aspartate--tRNA ligase, mitochondrion YHR034C 45.966408 INESSENTIAL biological_process unknown, molecular_function unknown, YBR026C 45.634664 INESSENTIAL MRF1 Nuclear protein that binds to T-rich strand of core consensus sequence of autonomously replicating sequence, respiration, DNA binding, nucleus YLR306W 45.546162 INESSENTIAL UBC12 Ubiquitin-conjugating enzyme, polyubiquitylation*, ubiquitin conjugating enzyme, cellular_component unknown YNL192W 45.516679 INESSENTIAL CHS1 chitin synthase 1, cytokinesis, chitin synthase, YER004W 45.289244 INESSENTIAL biological_process unknown, molecular_function unknown, YBR189W 45.206090 INESSENTIAL RPS9B Ribosomal protein S9B (S13) (rp21) (YS11), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YGL041C 45.143509 INESSENTIAL biological_process unknown, molecular_function unknown, YPL084W 45.055756 INESSENTIAL BRO1 BCK1-like resistance to osmotic shock, signal transduction, molecular_function unknown, cellular_component unknown YDR348C 44.992305 INESSENTIAL biological_process unknown, molecular_function unknown, YOR201C 44.705194 INESSENTIAL PET56 Ribose methyltransferase for mitochondrial 21S rRNA, ribosomal large subunit assembly and maintenance, rRNA (guanine-N1-)-methyltransferase, mitochondrion YHR154W 44.429943 INESSENTIAL ESC4 involved in silencing,molecular_function unknown, YGR155W 44.373713 INESSENTIAL CYS4 Cystathionine beta-synthase,cystathione beta-synthase, YDR101C 44.317414 INESSENTIAL biological_process unknown, molecular_function unknown, YDR405W 44.221455 INESSENTIAL MRP20 263-amino acid mitochondrial ribosomal large subunit protein; similar to L23 family of ribosomal proteins, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YHR167W 44.054181 INESSENTIAL THP2 biological_process unknown, molecular_function unknown, nucleus YDL061C 44.048330 INESSENTIAL RPS29B Ribosomal protein S29B (S36B) (YS29), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YNL199C 44.005421 INESSENTIAL GCR2 Transcription factor, glycolysis, YPR047W 44.004069 INESSENTIAL MSF1 alpha subunit of yeast mitochondrial phenylalanyl-tRNA synthetase, protein biosynthesis, phenylalanine--tRNA ligase, mitochondrion YML036W 43.440295 INESSENTIAL biological_process unknown, molecular_function unknown, YLR423C 43.360948 INESSENTIAL APG17 involved in autophagy, autophagy, molecular_function unknown, YPR100W 43.321279 INESSENTIAL biological_process unknown, molecular_function unknown, YDR065W 43.296026 INESSENTIAL biological_process unknown, molecular_function unknown, YBR268W 43.288619 INESSENTIAL MRPL37 Probable mitochondrial protein L37, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YMR067C 43.204845 INESSENTIAL biological_process unknown, molecular_function unknown, YPR106W 43.050527 INESSENTIAL ISR1 protein kinase,protein kinase, YLR148W 42.953235 INESSENTIAL PEP3 vacuolar membrane protein YMR284W 42.588819 INESSENTIAL YKU70 DNA binding protein, DNA repair, YER028C 42.507551 INESSENTIAL biological_process unknown, molecular_function unknown, YNL055C 42.322577 INESSENTIAL POR1 Outer mitochondrial membrane porin (voltage-dependent anion channel, or VDAC), transport, YNL297C 42.033751 INESSENTIAL MON2 molecular_function unknown YGL023C 41.983969 INESSENTIAL PIB2 similar to Fab1 and Vps27; involved in telomere-proximal repression of gene expression,molecular_function unknown, YHR191C 41.865339 INESSENTIAL CTF8 (putative) kinetochore protein YNL064C 41.815848 INESSENTIAL YDJ1 yeast dnaJ homolog (nuclear envelope protein); heat shock protein YPR040W 41.798513 INESSENTIAL SDF1 biological_process unknown, molecular_function unknown, YKL006W 41.641367 INESSENTIAL RPL14A Ribosomal protein L14A, protein biosynthesis, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YPR116W 41.539879 INESSENTIAL biological_process unknown, molecular_function unknown, YGL167C 41.214685 INESSENTIAL PMR1 Ca++-Pump, ATPase, transport, YMR014W 41.147817 INESSENTIAL BUD22 BUD site selection, biological_process unknown, molecular_function unknown, YNL323W 41.070101 INESSENTIAL LEM3 cell surface receptor linked signal transduction, molecular_function unknown, integral membrane protein YDR270W 41.064187 INESSENTIAL CCC2 Cu(2+)-transporting ATPase,hydrogen/potassium-exchanging ATPase, YAL023C 41.013311 INESSENTIAL PMT2 dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase, O-linked glycosylation, dolichyl-phosphate-mannose--protein mannosyltransferase, endoplasmic reticulum YGR160W 40.856260 INESSENTIAL FYV13 biological_process unknown, molecular_function unknown, cellular_component unknown YBR285W 40.818958 INESSENTIAL biological_process unknown, molecular_function unknown, YLL040C 40.689336 INESSENTIAL VPS13 component of peripheral vacuolar membrane protein complex YPR132W 40.665375 INESSENTIAL RPS23B Ribosomal protein S23B (S28B) (rp37) (YS14), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YCL037C 40.582338 INESSENTIAL SRO9 RNA binding protein with La motif YER014C-A 40.524503 INESSENTIAL BUD25 bud site selection, biological_process unknown, molecular_function unknown, cellular_component unknown YGL141W 40.425581 INESSENTIAL HUL5 ubiquitin-protein ligase (E3), polyubiquitylation*, ubiquitin--protein ligase, cellular_component unknown YGR076C 40.380882 INESSENTIAL MRPL25 Mitochondrial ribosomal protein MRPL25 (YmL25), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YDR137W 40.287062 INESSENTIAL RGP1 involved in mitotic growth, biological_process unknown, molecular_function unknown, YDR462W 40.277697 INESSENTIAL MRPL28 Mitochondrial ribosomal protein MRPL28 (YmL28), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YKR099W 40.165149 INESSENTIAL BAS1 transcription factor,transcription factor, YHR076W 40.104126 INESSENTIAL biological_process unknown, molecular_function unknown, YER154W 39.712666 INESSENTIAL OXA1 involved in cytochrome c oxidase and ATP synthase assembly, mitochondrial translocation, protein transporter, mitochondrial inner membrane YCR083W 39.466431 INESSENTIAL TRX3 mitochondrial thioredoxin, oxidative stress response, thioredoxin, mitochondrion YGR101W 39.340568 INESSENTIAL biological_process unknown, molecular_function unknown, YLL018C-A 39.326092 INESSENTIAL COX19 Cox19p (under characterization),molecular_function unknown, YGR086C 39.154163 INESSENTIAL biological_process unknown, molecular_function unknown, YKL032C 38.915469 INESSENTIAL IXR1 intrastrand crosslink recognition protein YBR163W 38.721251 INESSENTIAL DEM1 Weak similarity to Pta1p (pre-tRNA processing protein), biological_process unknown, molecular_function unknown, cellular_component unknown YNL185C 38.619564 INESSENTIAL MRPL19 mitochondrial ribosomal protein of the large subunit, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YLR447C 38.587029 INESSENTIAL VMA6 vacuolar ATPase V0 domain subunit d (36 kDa), vacuolar acidification*, hydrogen-transporting two-sector ATPase, vacuolar membrane* YGL013C 38.488673 INESSENTIAL PDR1 zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, transport, YHR064C 38.483690 INESSENTIAL PDR13 Hsp70 Protein YIL149C 38.447203 INESSENTIAL MLP2 colied-coil protein (putative), similar to myosin and TPR, protein-nucleus import, molecular_function unknown, nuclear membrane* YBL099W 38.336504 INESSENTIAL ATP1 mitochondrial F1F0-ATPase alpha subunit, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, catalytic core YDR500C 38.272076 INESSENTIAL RPL37B 60S ribosomal protein L37B (L43) (YL35), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YNL225C 38.168899 INESSENTIAL CNM67 Spindle pole body protein involved in nuclear migration, microtubule nucleation, structural protein of cytoskeleton, spindle pole body YMR205C 37.827179 INESSENTIAL PFK2 phosphofructokinase beta subunit, glycolysis, 6-phosphofructokinase, 6-phosphofructokinase YPR067W 37.772293 INESSENTIAL ISA2 Iron Sulfur Assembly -- IscA NifA homolog, iron transport, molecular_function unknown, mitochondrial intermembrane space YHR010W 37.526295 INESSENTIAL RPL27A Ribosomal protein L27A, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YJR090C 37.473223 INESSENTIAL GRR1 cyclin F box protein, ubiquitin-dependent protein degradation*, ubiquitin--protein ligase*, nuclear ubiquitin ligase complex YNL236W 37.434966 INESSENTIAL SIN4 component of RNA polymerase II holoenzyme mediator complex, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YKL073W 37.405461 INESSENTIAL LHS1 novel member of the Hsp70 family of molecular chaperones that localizes to the lumen of the endoplasmic reticulum: YMR116C 36.873168 INESSENTIAL ASC1 G-beta like protein YBR084C-A 36.831154 INESSENTIAL RPL19A Ribosomal protein L19A (L23A) (rpl5L) (YL14), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YER155C 36.720270 INESSENTIAL BEM2 Rho-type GTPase activating protein (GAP), establishment of cell polarity (sensu Saccharomyces)*, signal transducer*, intracellular YGL110C 36.719051 INESSENTIAL biological_process unknown, molecular_function unknown, YHR120W 36.698420 INESSENTIAL MSH1 mutS homolog involved in mitochondrial DNA repair, DNA repair, YDL192W 36.630082 INESSENTIAL ARF1 ADP-ribosylation factor, ER to Golgi transport*, ARF small monomeric GTPase, cytosol* YHR051W 36.379627 INESSENTIAL COX6 subunit VI of cytochrome c oxidase,cytochrome-c oxidase, YMR064W 36.352841 INESSENTIAL AEP1 basic, hydrophilic protein of 59 kDa, protein biosynthesis, molecular_function unknown, cellular_component unknown YDR318W 36.158197 INESSENTIAL MCM21 involved in minichromosome maintenance,molecular_function unknown, YNR052C 36.132329 INESSENTIAL POP2 Putative transcription factor YPL260W 36.087131 INESSENTIAL biological_process unknown, molecular_function unknown, YLR184W 36.075051 INESSENTIAL biological_process unknown, molecular_function unknown, YAL044C 36.002727 INESSENTIAL GCV3 H-protein subunit of the glycine cleavage system, glycine metabolism, YGL173C 35.673007 INESSENTIAL KEM1 cytoplasmic 5'-to-3' exonuclease., 35S primary transcript processing*, 5'-3' exoribonuclease, cytoplasm YCL063W 35.561887 INESSENTIAL biological_process unknown, molecular_function unknown, YOR008C 35.535213 INESSENTIAL KIM1 diepoxybutane and mitomycin C resistance,molecular_function unknown, YDL038C 35.474407 INESSENTIAL biological_process unknown, molecular_function unknown, YDL185W 35.377126 INESSENTIAL TFP1 vacuolar ATPase V1 domain subunit A (69 kDa), vacuolar acidification*, hydrogen-transporting two-sector ATPase*, hydrogen-transporting ATPase V1 domain YNR037C 35.316066 INESSENTIAL RSM19 protein of the small subunit of the mitochondrial ribosome YML056C 35.228943 INESSENTIAL IMD4 IMP dehydrogenase homolog, biological_process unknown, IMP dehydrogenase, cellular_component unknown YEL027W 34.857518 INESSENTIAL CUP5 vacuolar ATPase V0 domain subunit c (17 kDa), endocytosis*, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V0 domain YNL028W 34.809980 INESSENTIAL biological_process unknown, molecular_function unknown, YJL180C 34.682228 INESSENTIAL ATP12 (putative) involved F1F0-ATPase complex assembly, protein complex assembly, chaperone, mitochondrial matrix YGL101W 34.588293 INESSENTIAL biological_process unknown, molecular_function unknown, YGR261C 34.559612 INESSENTIAL APL6 putative beta adaptin component of the membrane-associate clathrin assembly complex YGL237C 34.552898 INESSENTIAL HAP2 transcriptional activator protein of CYC1 YGL244W 34.460987 INESSENTIAL RTF1 Nuclear protein, transcription, YNR036C 34.434435 INESSENTIAL biological_process unknown, molecular_function unknown, YDR377W 34.344291 INESSENTIAL ATP17 ATP synthase subunit f, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, F0 sector YNL252C 34.289595 INESSENTIAL MRPL17 mitochondrial ribosomal protein of the large subunit, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YGL026C 34.101198 INESSENTIAL TRP5 tryptophan synthetase,tryptophan synthase, YDR359C 34.052446 INESSENTIAL VID21 vacuolar import degradation,molecular_function unknown, YBR283C 34.029173 INESSENTIAL SSH1 Probable SEC61 protein homolog, co-translational membrane targeting, protein transporter, translocon YGL240W 33.983384 INESSENTIAL DOC1 component of the anaphase-promoting complex, ubiquitin-dependent protein degradation*, enzyme activator, anaphase-promoting complex YDL107W 33.897661 INESSENTIAL MSS2 cox1 pre-mRNA splicing factor,molecular_function unknown, YJR074W 33.891621 INESSENTIAL MOG1 nuclear protein that interacts with GTP-Gsp1p, biological_process unknown, molecular_function unknown, YAL046C 33.844905 INESSENTIAL biological_process unknown, molecular_function unknown, YGL105W 33.830173 INESSENTIAL ARC1 G4 nucleic acid binding protein, involved in tRNA aminoacylation YAL056W 33.812513 INESSENTIAL G protein effector, biological_process unknown, molecular_function unknown, YDL040C 33.782201 INESSENTIAL NAT1 N-terminal acetyltransferase, protein acetylation, peptide alpha-N-acetyltransferase, YDR467C 33.761203 INESSENTIAL biological_process unknown, molecular_function unknown, YOR241W 33.519297 INESSENTIAL MET7 Folylpolyglutamate synthetase,folylpolyglutamate synthase, YGR105W 33.483153 INESSENTIAL VMA21 vacuolar H+-ATPase assembly protein, vacuolar acidification, YDL013W 33.433534 INESSENTIAL HEX3 involved in hexose metabolism,molecular_function unknown, YGR200C 33.341446 INESSENTIAL ELP2 90 kD subunit of elongator and elongating RNA pol II holoenzyme, transcription, YBR200W 33.278058 INESSENTIAL BEM1 contains two SH3 domains YML061C 33.170060 INESSENTIAL PIF1 5' to 3' DNA helicase, DNA recombination*, DNA helicase, mitochondrion YJL127C 33.102381 INESSENTIAL SPT10 negative transcriptional regulator, chromatin modeling*, molecular_function unknown, nucleus YDR140W 33.057557 INESSENTIAL FYV9 biological_process unknown, molecular_function unknown, cellular_component unknown YDR268W 32.802745 INESSENTIAL MSW1 mitochondrial tryptophanyl-tRNA synthetase,tryptophan--tRNA ligase, YBR194W 32.556775 INESSENTIAL biological_process unknown, molecular_function unknown, cytoplasm YJL062W 32.323117 INESSENTIAL LAS21 putative membrane protein, a member of the major facilitator super family, biological_process unknown, YOR199W 32.304420 INESSENTIAL biological_process unknown, molecular_function unknown, YGL058W 32.195169 INESSENTIAL RAD6 Ubiquitin conjugating (E2) enzyme. The C-terminal 23 residues are critical for sporulation and histone polyubiquitinating activity, but not UV repair or induced mutagenesis., ubiquitin-dependent protein degradation*, ubiquitin conjugating enzyme, nucleus YAL048C 32.170721 INESSENTIAL molecular_function unknown YDR200C 32.125136 INESSENTIAL biological_process unknown, molecular_function unknown, YPL193W 32.047923 INESSENTIAL RSA1 RiboSome Assembly, ribosomal large subunit assembly and maintenance, molecular_function unknown, nucleoplasm YKL100C 31.743697 INESSENTIAL biological_process unknown, molecular_function unknown, YLR382C 31.734515 INESSENTIAL NAM2 mitochondrial leucyl tRNA synthetase,leucine--tRNA ligase, YOR187W 31.718916 INESSENTIAL TUF1 Translation elongation factor Tu, mitochondrial YNL210W 31.672321 INESSENTIAL MER1 encodes protein with RNA-binding motifs required for MRE2-dependent mRNA splicing, meiosis, pre-mRNA splicing factor, nucleus YLR372W 31.612004 INESSENTIAL SUR4 involved in fatty acid biosynthesis, fatty acid biosynthesis*, molecular_function unknown, endoplasmic reticulum membrane YJL047C 31.335547 INESSENTIAL RTT101 Regulator of Ty1 Transposition,molecular_function unknown, YJR030C 31.278213 INESSENTIAL biological_process unknown, molecular_function unknown, YLR312W-A 31.152125 INESSENTIAL MRPL15 Mitochondrial ribosomal protein MRPL15 (YmL15), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YMR228W 30.945707 INESSENTIAL MTF1 Mitochondrial RNA polymerase specificity factor, transcription from mitochondrial promoter, transcription factor, mitochondrial matrix YMR078C 30.863459 INESSENTIAL CTF18 (putative) involved in chromosome transmission during mitosis,molecular_function unknown, YHR142W 30.579958 INESSENTIAL CHS7 The seventh gene identified that is involved in chitin synthesis; involved in Chs3p export from the ER YIR026C 30.496930 INESSENTIAL YVH1 nitrogen starvation-induced protein phosphatase, meiosis*, protein tyrosine phosphatase, YNL030W 30.049637 INESSENTIAL HHF2 Histone H4 (HHF1 and HHF2 code for identical proteins) YMR024W 29.943561 INESSENTIAL MRPL3 Mitochondrial ribosomal protein MRPL3 (YmL3), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YEL061C 29.850166 INESSENTIAL CIN8 kinesin-related protein involved in establishment and maintenance of mitotic spindle, mitotic chromosome segregation*, microtubule motor, kinesin* YML010C-B 29.811747 INESSENTIAL biological_process unknown, molecular_function unknown, YDR057W 29.741660 INESSENTIAL biological_process unknown, molecular_function unknown, YIL098C 29.474852 INESSENTIAL FMC1 Formation of Mitochondrial Cytochromes 1 YGR257C 29.423688 INESSENTIAL biological_process unknown, molecular_function unknown, YGR215W 28.985145 INESSENTIAL RSM27 protein of the small subunit of the mitochondrial ribosome YLR192C 28.931429 INESSENTIAL HCR1 High Copy suppressor of RPG1, biological_process unknown, molecular_function unknown, YJL046W 28.731179 INESSENTIAL biological_process unknown, molecular_function unknown, YIL049W 28.673384 INESSENTIAL DFG10 involved in filamentous growth,molecular_function unknown, YML073C 28.663484 INESSENTIAL RPL6A Ribosomal protein L6A (L17A) (rp18) (YL16), protein biosynthesis*, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YOR196C 28.606580 INESSENTIAL LIP5 lipoic acid synthase, fatty acid metabolism, YNL320W 28.400462 INESSENTIAL biological_process unknown, molecular_function unknown, YGR037C 28.349112 INESSENTIAL ACB1 Acyl-CoA-binding protein (ACBP) Diazepam binding inhibitor (DBI) endozepine (EP), fatty acid metabolism, acyl-CoA binding, cellular_component unknown YPL262W 28.309484 INESSENTIAL FUM1 mitochondrial and cytoplasmic fumarase (fumarate hydralase), tricarboxylic acid cycle*, fumarate hydratase, cytosol* YOR014W 28.245964 INESSENTIAL RTS1 B-type regulatory subunit of protein phosphatase 2A (PP2A), protein biosynthesis, protein phosphatase type 2A, protein phosphatase type 2A YDR471W 28.166243 INESSENTIAL RPL27B Ribosomal protein L27B, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YMR072W 27.945692 INESSENTIAL ABF2 HMG-1 homolog, mitochondrial, mitochondrial genome maintenance, YPL005W 27.879380 INESSENTIAL biological_process unknown, molecular_function unknown, YMR060C 27.879320 INESSENTIAL TOM37 mitochondrial import receptor, heterodimerizes with Tom70p, preferentially recognizes the mature regions of precursor proteins associated with ATP-dependent cytosolic chaperones, mitochondrial translocation, protein transporter, mitochondrial outer membrane translocase complex YJL175W 27.814345 INESSENTIAL biological_process unknown, molecular_function unknown, YMR266W 27.780917 INESSENTIAL RSN1 biological_process unknown, molecular_function unknown, YCR071C 27.765481 INESSENTIAL IMG2 similar to Drosophila gonadal protein Z600; involved in mitochondrial DNA maitenance,molecular_function unknown, YDR509W 27.636966 INESSENTIAL biological_process unknown, molecular_function unknown, YGL072C 27.575324 INESSENTIAL biological_process unknown, molecular_function unknown, YDL032W 27.451223 INESSENTIAL biological_process unknown, molecular_function unknown, YLR268W 26.988697 INESSENTIAL SEC22 Synaptobrevin (v-SNARE) homolog, non-selective vesicle fusion*, v-SNARE, inter-Golgi transport vesicle* YJL028W 26.511943 INESSENTIAL biological_process unknown, molecular_function unknown, YPR148C 26.511085 INESSENTIAL biological_process unknown, molecular_function unknown, YHR021C 26.336489 INESSENTIAL RPS27B 40S Ribosomal protein S27B (rp61) (YS20), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YHR203C 26.047204 INESSENTIAL RPS4B Ribosomal protein S4B (YS6) (rp5) (S7B), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YGL095C 25.998741 INESSENTIAL VPS45 cytosolic and peripheral membrane protein, Golgi to vacuole transport*, vacuolar assembly, Golgi-vacuole transport vesicle YDR519W 25.881870 INESSENTIAL FKB2 FKBP (FK506 binding protein) 13; peptidylprolyl cis-trans isomerase activity, biological_process unknown, peptidylprolyl isomerase, endoplasmic reticulum membrane YKL009W 25.330694 INESSENTIAL MRT4 involved in mRNA decay,molecular_function unknown, YGL108C 25.258028 INESSENTIAL biological_process unknown, molecular_function unknown, YPR099C 25.202258 INESSENTIAL biological_process unknown, molecular_function unknown, YNL156C 25.152922 INESSENTIAL biological_process unknown, molecular_function unknown, YDR315C 25.000996 INESSENTIAL IPK1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IP5 2-kinase) YDR293C 24.993667 INESSENTIAL SSD1 cell cycle, RNA binding, cytoplasm YDR529C 24.985876 INESSENTIAL QCR7 ubiquinol-cytochrome c oxidoreductase subunit 7 (14 kDa),ubiquinol-cytochrome-c reductase, YLR185W 24.899227 INESSENTIAL RPL37A 60S ribosomal protein L37A (L43) (YL35), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YEL051W 24.675528 INESSENTIAL VMA8 vacuolar ATPase V1 domain subunit D, vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V1 domain YHR057C 24.567977 INESSENTIAL CYP2 Peptidylprolyl isomerase (cyclophilin) ER or secreted, stress response, peptidylprolyl isomerase, cellular_component unknown YDL191W 24.364736 INESSENTIAL RPL35A Ribosomal protein L35A, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YLR091W 24.285028 INESSENTIAL biological_process unknown, molecular_function unknown, YLR079W 24.206568 INESSENTIAL SIC1 Cdc28p-Clb5 protein kinase inhibitor YDL033C 24.074476 INESSENTIAL YLR182W 23.932281 INESSENTIAL SWI6 transcription factor, cell cycle, transcription factor, YDL128W 23.920279 INESSENTIAL VCX1 vacuolar H+ Ca2+ exchanger, transport, YDR043C 23.890091 INESSENTIAL NRG1 transcriptional repressor which can bind to UAS-1 in the STA1 promoter and which can interact with Ssn6p, biological_process unknown, molecular_function unknown, YLR396C 23.542497 INESSENTIAL VPS33 involved in vacuolar protein targeting YNL330C 23.385328 INESSENTIAL RPD3 histone deacetylase, chromatin architecture*, histone deacetylase, histone deacetylase complex YDR069C 22.914245 INESSENTIAL DOA4 ubiquitin isopeptidase, deubiquitylation*, ubiquitin-specific protease, 26S proteasome YOR211C 22.871050 INESSENTIAL MGM1 encodes protein with GTP-binding domain related to dynamin, mitochondrion organization and biogenesis*, GTPase, mitochondrial outer membrane YGR096W 22.867134 INESSENTIAL biological_process unknown, molecular_function unknown, YMR307W 22.858759 INESSENTIAL GAS1 cell surface glycoprotein 115-120 kDa, biological_process unknown, YKL002W 22.667314 INESSENTIAL DID4 biological_process unknown, molecular_function unknown, YER122C 22.598046 INESSENTIAL GLO3 Zinc-finger-containing protein with similarity to Gcs1p and Sps18p, ER to Golgi transport*, ARF GTPase activator, secretory vesicle* YOR139C 22.535032 INESSENTIAL biological_process unknown, molecular_function unknown, YDR173C 22.381810 INESSENTIAL ARG82 dual-specificity inositol 1,4,5-trisphosphate 6-kinase inositol 1,4,5,6-tetrakisphosphate 3-kinase (IP3 6- IP4 3-kinase) YER054C 22.231406 INESSENTIAL GIP2 (putative) regulator of Glc7, a PP1 family protein phosphatase YDR320C 22.099830 INESSENTIAL SWA2 Auxilin-like protein,molecular_function unknown, YNL250W 21.914953 INESSENTIAL RAD50 Contains a purine-binding domain, two heptad repeats and a hydrophobic tail., DNA repair, YDR017C 21.868281 INESSENTIAL KCS1 Shows homology to basic leucine zipper family of transcription factors YDR347W 21.657307 INESSENTIAL MRP1 37 kDa mitochondrial ribosomal protein, protein biosynthesis, structural protein of ribosome, mitochondrial small ribosomal-subunit YJR018W 21.626943 INESSENTIAL biological_process unknown, molecular_function unknown, YOL087C 21.318409 INESSENTIAL biological_process unknown, molecular_function unknown, YLR322W 21.252035 INESSENTIAL biological_process unknown, molecular_function unknown, YDR115W 21.139314 INESSENTIAL biological_process unknown, molecular_function unknown, YPL234C 21.051545 INESSENTIAL TFP3 vacuolar ATPase V0 domain subunit c' (17 kDa), vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V0 domain YPL078C 20.830618 INESSENTIAL ATP4 F(1)F(0)-ATPase complex delta subunit, mitochondrial, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, stator stalk YBR271W 20.523519 INESSENTIAL biological_process unknown, molecular_function unknown, YKR060W 20.441951 INESSENTIAL biological_process unknown, molecular_function unknown, YBR156C 20.416152 INESSENTIAL SLI15 Mitotic spindle protein involved in chromosome segregation.,molecular_function unknown, YBR112C 20.343466 INESSENTIAL CYC8 Transcription regulatory protein, transcription, YLR338W 20.199683 INESSENTIAL KRE21 biological_process unknown, molecular_function unknown, YAR002W 20.128423 INESSENTIAL NUP60 nuclear pore protein YPL087W 20.126973 INESSENTIAL YDC1 alkaline dihydroceramidase with minor reverse activity., sphingolipid metabolism, YML063W 20.065711 INESSENTIAL RPS1B Ribosomal protein S1B (rp10B), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDR448W 20.049083 INESSENTIAL ADA2 transcription factor, member of ADA and SAGA, two transcriptional adaptor HAT (histone acetyltransferase)complexes SAGA complex YDR323C 20.024510 INESSENTIAL PEP7 cytosolic and peripheral membrane protein with three zinc fingers; cysteine rich regions of amino acids are essential for function, non-selective vesicle fusion*, vesicle fusion, cytoplasm* YKL170W 19.992867 INESSENTIAL MRPL38 mitochondrial ribosomal protein L14, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YKL114C 19.851049 INESSENTIAL APN1 major apurinic apyrimidinic endonuclease 3'-repair diesterase,DNA-(apurinic or apyrimidinic site) lyase, YMR188C 19.784120 INESSENTIAL biological_process unknown, molecular_function unknown, YPL173W 19.783604 INESSENTIAL MRPL40 Mitochondrial ribosomal protein MRPL40 (YmL40), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YNL296W 19.591279 INESSENTIAL KRE25 biological_process unknown, molecular_function unknown, YPR072W 19.557697 INESSENTIAL NOT5 member of the NOT complex, a global negative regulator of transcription, transcription, YNL229C 19.468821 INESSENTIAL URE2 transcriptional regulator, putative glutathione transferase, nitrogen utilization regulation, transcription co-repressor, soluble fraction YDR363W 19.308300 INESSENTIAL ESC2 establishes silent chromatin,molecular_function unknown, YNL248C 18.986196 INESSENTIAL RPA49 49-kDa alpha subunit of RNA polymerase A, transcription from Pol I promoter, DNA-directed RNA polymerase I, DNA-directed RNA polymerase I YPR044C 18.909601 INESSENTIAL biological_process unknown, molecular_function unknown, YGL127C 18.843763 INESSENTIAL SOH1 SOH1 encodes a novel 14-kD protein with limited sequence similarity to RNA polymerases. The Soh1 protein interacts with a DNA repair protein, Rad5p, in a two-hybrid system assay., biological_process unknown, molecular_function unknown, YPL062W 18.616619 INESSENTIAL biological_process unknown, molecular_function unknown, YDR076W 18.592215 INESSENTIAL RAD55 RecA homolog (related to DMC1, RAD51, RAD57), interacts with Rad51p and Rad57p by two-hybrid analysis YNL315C 18.355070 INESSENTIAL ATP11 F1FO ATPase assembly protein, protein complex assembly, chaperone, mitochondrial matrix YLR217W 18.315877 INESSENTIAL biological_process unknown, molecular_function unknown, cellular_component unknown YDR525W 18.233706 INESSENTIAL biological_process unknown, molecular_function unknown, YMR041C 18.196918 INESSENTIAL biological_process unknown, molecular_function unknown, YNL073W 18.132152 INESSENTIAL MSK1 mitochondrial lysine-tRNA synthetase,lysine--tRNA ligase, YPL042C 18.085386 INESSENTIAL SSN3 a cyclin(SSN8)-dependent serine threonine protein kinase, protein phosphorylation*, non-specific RNA polymerase II transcription factor*, transcription factor complex YLR149C 17.990042 INESSENTIAL biological_process unknown, molecular_function unknown, YOL095C 17.938064 INESSENTIAL HMI1 mitochondrial DNA helicase (putative), biological_process unknown, YMR038C 17.743119 INESSENTIAL LYS7 copper chaperone for superoxide dismutase Sod1p, oxidative stress response, YDR363W-A 17.728920 INESSENTIAL SEM1 unknown function, similar to S. pombe Dss1,molecular_function unknown, YNL146W 17.641233 INESSENTIAL biological_process unknown, molecular_function unknown, YNR073C 17.582066 INESSENTIAL biological_process unknown, molecular_function unknown, YGL016W 17.211623 INESSENTIAL KAP122 karyopherin-beta family protein YHR047C 17.204544 INESSENTIAL AAP1 arginine alanine aminopeptidase, biological_process unknown, aminopeptidase, cellular_component unknown YLR374C 17.138569 INESSENTIAL biological_process unknown, molecular_function unknown, YGR167W 17.117741 INESSENTIAL CLC1 Clathrin light chain YDR237W 17.081973 INESSENTIAL MRPL7 Mitochondrial ribosomal protein MRPL7 (YmL7), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YGR171C 17.064267 INESSENTIAL MSM1 mitochondrial methionyl-tRNA synthetase,methionine--tRNA ligase, YML095C-A 17.061551 INESSENTIAL biological_process unknown, molecular_function unknown, YDR375C 16.977923 INESSENTIAL BCS1 Mitochondrial ATPase (AAA family), respiration, adenosinetriphosphatase, mitochondrial inner membrane YBR025C 16.878999 INESSENTIAL probable purine nucleotide-binding protein, biological_process unknown, molecular_function unknown, cytoplasm YGL135W 16.792041 INESSENTIAL RPL1B Ribosomal protein L1B, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YGR272C 16.726839 INESSENTIAL biological_process unknown, molecular_function unknown, YCR046C 16.493664 INESSENTIAL IMG1 mitochondrial ribosomal protein, protein biosynthesis, structural protein of ribosome, mitochondrial ribosome YDR163W 16.459034 INESSENTIAL biological_process unknown, molecular_function unknown, YBR133C 16.343704 INESSENTIAL HSL7 regulator of Swe1p kinase, bud growth*, protein kinase inhibitor, cytokinetic ring (sensu Saccharomyces) YPL040C 16.320152 INESSENTIAL ISM1 nuclear encoded mitochondrial isoleucyl-tRNA synthetase,isoleucine--tRNA ligase, YBR162C 16.167442 INESSENTIAL TOS1 YOL121C 16.150262 INESSENTIAL RPS19A 40S ribosomal protein S19A (S16aA) (rp55A) (YS16A), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDR431W 16.148262 INESSENTIAL biological_process unknown, molecular_function unknown, YDL151C 16.084440 INESSENTIAL FYV3 biological_process unknown, molecular_function unknown, cellular_component unknown YDR121W 16.073294 INESSENTIAL DPB4 DNA polymerase II (epsilon) 4th subunit, lagging strand elongation*, epsilon DNA polymerase, epsilon DNA polymerase YDR495C 15.821114 INESSENTIAL VPS3 vacuolar protein targeting protein YKL118W 15.813665 INESSENTIAL biological_process unknown, molecular_function unknown, YOL115W 15.756468 INESSENTIAL TRF4 homologous to Trf5p and Top1p, associates with Smc1p and Smc2p, mitotic chromosome condensation*, DNA-directed DNA polymerase, nucleus YBL081W 15.754580 INESSENTIAL biological_process unknown, molecular_function unknown, YMR275C 15.644374 INESSENTIAL BUL1 Rsp5p ubiquitin ligase binding protein, polyubiquitylation*, molecular_function unknown, plasma membrane YGL076C 15.363258 INESSENTIAL RPL7A Ribosomal protein L7A (L6A) (rp11) (YL8), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YMR269W 15.257470 INESSENTIAL biological_process unknown, molecular_function unknown, YKL134C 15.200295 INESSENTIAL 1 mitochondrial intermediate peptidase, possesses octapeptidyl amino-peptidase activity, iron homeostasis*, metallopeptidase, mitochondrion YGL025C 15.179878 INESSENTIAL PGD1 RNA polymerase II mediator subunit, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YLR069C 14.824493 INESSENTIAL MEF1 mitochondrial elongation factor G-like protein, protein synthesis elongation, translation elongation factor, mitochondrion YGL168W 14.775550 INESSENTIAL biological_process unknown, molecular_function unknown, YCL047C 14.756762 INESSENTIAL biological_process unknown, molecular_function unknown, YGL071W 14.674081 INESSENTIAL RCS1 Putative transcription factor that binds the consensus site PyPuCACCCPu, iron transport, YLL027W 14.666387 INESSENTIAL ISA1 Iron Sulfur Assembly -- IscA NifA homolog, iron transport, molecular_function unknown, mitochondrial matrix YNL037C 14.608884 INESSENTIAL IDH1 alpha-4-beta-4 subunit of mitochondrial isocitrate dehydrogenase 1, tricarboxylic acid cycle*, isocitrate dehydrogenase (NAD+), mitochondrial matrix YER117W 14.530491 INESSENTIAL RPL23B Ribosomal protein L23B (L17aB) (YL32), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YPL183W-A 14.471263 INESSENTIAL protein biosynthesis, structural protein of ribosome, mitochondrion YOR312C 14.441398 INESSENTIAL RPL20B 60S ribosomal protein L20B (L18B), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YNL080C 14.251658 INESSENTIAL biological_process unknown, molecular_function unknown, YPL157W 14.231324 INESSENTIAL biological_process unknown, molecular_function unknown, YCR077C 14.166316 INESSENTIAL PAT1 Necessary for accurate chromosome transmission during cell YDR127W 14.133192 INESSENTIAL ARO1 pentafunctional arom polypeptide (contains: 3-dehydroquinate synthase, 3-dehydroquinate dehydratase (3-dehydroquinase), shikimate 5-dehydrogenase, shikimate kinase, and epsp synthase),3-dehydroquinate dehydratase, YCR024C 14.121011 INESSENTIAL Asn-tRNA synthetase, protein biosynthesis, asparagine--tRNA ligase*, mitochondrion YOL033W 14.034742 INESSENTIAL MSE1 Mitochondrial glutamyl-tRNA synthetase,glutamate--tRNA ligase, YOR006C 13.999829 INESSENTIAL biological_process unknown, molecular_function unknown, YIL037C 13.935889 INESSENTIAL PRM2 pheromone-regulated membrane protein, mating (sensu Saccharomyces), molecular_function unknown, integral membrane protein YEL033W 13.823270 INESSENTIAL biological_process unknown, molecular_function unknown, YFL025C 13.821749 INESSENTIAL BST1 negative regulator of COPII vesicle formation YHR194W 13.795366 INESSENTIAL biological_process unknown, molecular_function unknown, YBR221C 13.630488 INESSENTIAL PDB1 beta subunit of pyruvate dehydrogenase (E1 beta),pyruvate dehydrogenase (lipoamide), YJR121W 13.592565 INESSENTIAL ATP2 F(1)F(0)-ATPase complex beta subunit, mitochondrial, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, catalytic core YLR260W 13.547349 INESSENTIAL LCB5 sphingoid long chain base (LCB) kinase, sphingolipid metabolism, YPR123C 13.508886 INESSENTIAL biological_process unknown, molecular_function unknown, YBR181C 13.468818 INESSENTIAL RPS6B 40S ribosomal gene product S6B (S10B) (rp9) (YS4), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YJR118C 13.364679 INESSENTIAL ILM1 molecular_function unknown YMR190C 13.285275 INESSENTIAL SGS1 has DNA helicase signature motifs YKL077W 13.222053 INESSENTIAL biological_process unknown, molecular_function unknown, YMR287C 13.209315 INESSENTIAL MSU1 component of 3'-5'exonuclease complex YIL060W 13.201067 INESSENTIAL biological_process unknown, molecular_function unknown, YDR028C 13.159274 INESSENTIAL REG1 regulator of phosphatase Glc7p, involved in glucose repression, glycogen metabolism*, protein phosphatase type 1, cytoplasm* YCR003W 13.023011 INESSENTIAL MRPL32 Mitochondrial ribosomal protein MRPL32 (YmL32), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YNL184C 12.887343 INESSENTIAL biological_process unknown, molecular_function unknown, YLR403W 12.736003 INESSENTIAL SFP1 split zinc finger protein, biological_process unknown, YKL138C 12.681875 INESSENTIAL MRPL31 15.5 kDa mitochondrial ribosomal protein YmL31, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YGR126W 12.523488 INESSENTIAL biological_process unknown, molecular_function unknown, YKL119C 12.493812 INESSENTIAL VPH2 25.2 kDa protein involved in assembly of vacuolar H(+) ATPase, vacuolar acidification*, molecular_function unknown, endoplasmic reticulum membrane YLR083C 12.467563 INESSENTIAL EMP70 endosomal membrane protein YBR289W 12.366712 INESSENTIAL SNF5 subunit of the chromatin remodeling Snf Swi complex, chromatin modeling, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex YDL202W 12.299979 INESSENTIAL MRPL11 Mitochondrial ribosomal protein MRPL11 (YmL11), protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YPL097W 12.262667 INESSENTIAL MSY1 Tyrosyl-tRNA synthetase,tyrosine--tRNA ligase, YDR161W 12.201103 INESSENTIAL TCI1 interacts with PP2C, biological_process unknown, YOR295W 12.166828 INESSENTIAL biological_process unknown, molecular_function unknown, YPL017C 11.835708 INESSENTIAL biological_process unknown, molecular_function unknown, YDR447C 11.734642 INESSENTIAL RPS17B Ribosomal protein S17B (rp51B), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YAL035W 11.606219 INESSENTIAL FUN12 97 kDa protein, biological_process unknown, molecular_function unknown, YBR267W 11.475775 INESSENTIAL Probable Zn-finger protein (C2H2 type), biological_process unknown, molecular_function unknown, YGL038C 11.462457 INESSENTIAL OCH1 membrane-bound alpha-1,6-mannosyltransferase, N-linked glycoprotein maturation, alpha-1,6-mannosyltransferase, YOR366W 11.327795 INESSENTIAL biological_process unknown, molecular_function unknown, YGL118C 11.256913 INESSENTIAL biological_process unknown, molecular_function unknown, YOR080W 11.143821 INESSENTIAL DIA2 Digs Into Agar, invasive growth, molecular_function unknown, cellular_component unknown YGL107C 11.137542 INESSENTIAL biological_process unknown, molecular_function unknown, YML122C 11.135171 INESSENTIAL biological_process unknown, molecular_function unknown, YIL040W 11.061886 INESSENTIAL biological_process unknown, molecular_function unknown, YMR312W 10.998635 INESSENTIAL biological_process unknown, molecular_function unknown, YEL003W 10.972061 INESSENTIAL GIM4 bovine prefoldin subunit 2 homolog (putative), protein folding, YLR226W 10.943034 INESSENTIAL BUR2 involved in transcriptional regulation, mitotic chromosome segregation, molecular_function unknown, cellular_component unknown YLR042C 10.929505 INESSENTIAL biological_process unknown, molecular_function unknown, YML124C 10.877462 INESSENTIAL TUB3 alpha-tubulin, mitotic chromosome segregation*, structural protein of cytoskeleton, spindle pole body* YPR191W 10.850479 INESSENTIAL QCR2 40 kDa ubiquinol cytochrome-c reductase core protein 2,ubiquinol-cytochrome-c reductase, YLL045C 10.835898 INESSENTIAL RPL8B Ribosomal protein L8B (L4B) (rp6) (YL5), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YJL029C 10.738075 INESSENTIAL VPS53 Vps53p is a hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p.,molecular_function unknown, YDL160C 10.737972 INESSENTIAL DHH1 (putative) DEAD box RNA helicase, transcription, RNA helicase, YDR184C 10.607798 INESSENTIAL ATC1 nuclear protein that interacts with Aip3 YOL051W 10.593166 INESSENTIAL GAL11 Component of the RNA polymerase II holoenzyme complex, positive and negative transcriptional regulator of genes involved in mating-type specialization, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YOR359W 10.496476 INESSENTIAL biological_process unknown, molecular_function unknown, YBR278W 10.488261 INESSENTIAL DPB3 C and C' subunits of DNA polymerase II, nucleotide-excision repair*, epsilon DNA polymerase, replication fork YGR162W 10.403526 INESSENTIAL TIF4631 mRNA cap-binding protein (eIF-4F), 150K subunit , highly homologous to Tif4632p, homologs of mammalian p220, protein synthesis initiation, translation initiation factor, ribosome YPL061W 10.373243 INESSENTIAL ALD6 Cytosolic Aldehyde Dehydrogenase, carbohydrate metabolism*, aldehyde dehydrogenase, cytoplasm YNL147W 10.369984 INESSENTIAL LSM7 Sm-like protein YDL056W 10.338609 INESSENTIAL MBP1 transcription factor, cell cycle control*, transcription factor, nucleus YDR162C 10.316943 INESSENTIAL NBP2 interacts with Nap1, which is involved in histone assembly, biological_process unknown, YGR078C 10.113515 INESSENTIAL PAC10 Polypeptide 3 of a Yeast Non-native Actin Binding Complex, homolog of a component of the bovine NABC complex, tubulin folding, molecular_function unknown, cellular_component unknown YNL120C 10.111854 INESSENTIAL biological_process unknown, molecular_function unknown, YPL158C 10.073223 INESSENTIAL biological_process unknown, molecular_function unknown, YKR057W 10.036210 INESSENTIAL RPS21A Ribosomal protein S21A (S26A) (YS25), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YNL069C 9.999963 INESSENTIAL RPL16B Ribosomal protein L16B (L21B) (rp23) (YL15), protein biosynthesis, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YNL054W 9.982350 INESSENTIAL VAC7 Integral vacuolar membrane protein,molecular_function unknown, YLR439W 9.917703 INESSENTIAL MRPL4 Mitochondrial 60S ribosomal protein L4, protein biosynthesis, structural protein of ribosome, mitochondrial large ribosomal-subunit YNL177C 9.911636 INESSENTIAL biological_process unknown, molecular_function unknown, YHR081W 9.882132 INESSENTIAL biological_process unknown, molecular_function unknown, YLR337C 9.868226 INESSENTIAL VRP1 Proline-rich protein verprolin, actin filament organization*, actin binding, actin cortical patch (sensu Saccharomyces) YDL115C 9.743249 INESSENTIAL biological_process unknown, molecular_function unknown, YLR073C 9.741628 INESSENTIAL biological_process unknown, molecular_function unknown, YLR358C 9.671333 INESSENTIAL biological_process unknown, molecular_function unknown, YDL035C 9.653067 INESSENTIAL GPR1 G-protein coupled receptor YPL239W 9.629343 INESSENTIAL YAR1 YAR1 encodes a 200-amino-acid protein with two ANK repeat motifs and an acidic C terminus rich in PEST-like sequences, biological_process unknown, molecular_function unknown, YOR034C 9.576339 INESSENTIAL AKR2 involved in constitutive endocytosis of Ste3p,molecular_function unknown, YJL077C 9.508128 INESSENTIAL ICS3 Increased Copper Sensitivity,molecular_function unknown, YKL204W 9.432802 INESSENTIAL EAP1 probable purine nucleotide-binding protein, translational regulation, initiation, adenosinetriphosphatase, eukaryotic translation initiation factor 4F complex YDL106C 9.404593 INESSENTIAL PHO2 Homeobox-domain containing transcription fractor which is a positive regulator of PHO5 and other genes.,transcription factor, YDR533C 9.403454 INESSENTIAL biological_process unknown, molecular_function unknown, YGR231C 9.377477 INESSENTIAL PHB2 mitochondrial protein, prohibitin homolog; homolog of mammalian BAP37 and S. cerevisiae Phb1p, proteolysis and peptidolysis*, molecular_function unknown, mitochondrion YAL012W 9.366425 INESSENTIAL CYS3 cystathionine gamma-lyase,cystathionine-gamma-lyase, YKR092C 9.334929 INESSENTIAL SRP40 nucleolar protein that is immunologically and structurally related to rat Nopp140, a nonribosomal protein of the nucleolus and coiled bodies., nucleocytoplasmic transport, chaperone, nucleolus YGL163C 9.283614 INESSENTIAL RAD54 DNA-dependent ATPase, DNA repair, YLR239C 9.189502 INESSENTIAL biological_process unknown, molecular_function unknown, YCL061C 9.158571 INESSENTIAL biological_process unknown, molecular_function unknown, YJL007C 9.144955 INESSENTIAL biological_process unknown, molecular_function unknown, YJL124C 9.140259 INESSENTIAL LSM1 involved in mRNA stablity YPL050C 9.062493 INESSENTIAL MNN9 Protein required for complex glycosylation, protein glycosylation, YDL130W 9.021062 INESSENTIAL RPP1B Ribosomal protein P1B (L44') (YP1beta) (Ax), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YDR486C 9.009931 INESSENTIAL VPS60 biological_process unknown, molecular_function unknown, cellular_component unknown YMR207C 8.956760 INESSENTIAL HFA1 Similar to acetyl-coenzyme A carboxylase, biological_process unknown, molecular_function unknown, YDR340W 8.889285 INESSENTIAL biological_process unknown, molecular_function unknown, YBR048W 8.880474 INESSENTIAL RPS11B Ribosomal protein S11B (S18B) (rp41B) (YS12), protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YPL132W 8.828892 INESSENTIAL COX11 mitochondrial membrane protein required for insertion of Cu(B) and magnesium during assembly of cytochrome c oxidase, respiration, molecular_function unknown, mitochondrial inner membrane YGL064C 8.697243 INESSENTIAL biological_process unknown, molecular_function unknown, YGR220C 8.692272 INESSENTIAL MRPL9 Mitochondrial ribosomal protein MRPL9 (YmL9) (E. coli L3) (human MRL3), protein biosynthesis*, structural protein of ribosome*, mitochondrial large ribosomal-subunit YDR283C 8.519870 INESSENTIAL GCN2 eukaryotic initiation factor 2 alpha (eIF2-alpha) kinase YHR067W 8.498297 INESSENTIAL biological_process unknown, molecular_function unknown, YDR369C 8.481016 INESSENTIAL XRS2 DNA repair protein YDL175C 8.440315 INESSENTIAL biological_process unknown, molecular_function unknown, YER056C-A 8.412243 INESSENTIAL RPL34A Ribosomal protein L34A, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YGR016W 8.385204 INESSENTIAL biological_process unknown, molecular_function unknown, YOR369C 8.290474 INESSENTIAL RPS12 40S ribosomal protein S12, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YER044C 8.256833 INESSENTIAL ERG28 ergosterol biosynthesis, molecular_function unknown, cellular_component unknown YIL097W 8.153299 INESSENTIAL FYV10 biological_process unknown, molecular_function unknown, cellular_component unknown YER151C 8.051618 INESSENTIAL UBP3 Ubiquitin-specific protease, deubiquitylation, ubiquitin-specific protease, cytoplasm YJR055W 8.003395 INESSENTIAL HIT1 involved in growth at high temperature, biological_process unknown, YML032C 7.962507 INESSENTIAL RAD52 Required for X-ray damage repair and various types of intra-and interchromosomal mitotic recombination, including HO switching and plasmid exchange. Dispensable for premeiotic DNA synthesis, double strand breaks, synaptonemal complexes, and heteroduplex formation, but generally required for completion of meiotic recombination. RAD52 controls the level of a 72 kd endo-exonuclease in log phase and sporulation. Interacts with Rad51p by two hybrid analysis. mRNA is induced in meiosis during recombination. YGR112W 7.742136 INESSENTIAL SHY1 mitochondrial protein with homology to the mammalian SURF-1 gene, respiration, molecular_function unknown, mitochondrial inner membrane YDR073W 7.713625 INESSENTIAL SNF11 component of SWI SNF global transcription activator complex, chromatin modeling, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex YER178W 7.630428 INESSENTIAL PDA1 alpha subunit of pyruvate dehydrogenase (E1 alpha),pyruvate dehydrogenase (lipoamide), YDR477W 7.590309 INESSENTIAL SNF1 protein serine threonine kinase, protein phosphorylation*, SNF1A/AMP-activated protein kinase, cytoplasm YDL095W 7.564068 INESSENTIAL PMT1 dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase, O-linked glycosylation, dolichyl-phosphate-mannose--protein mannosyltransferase, endoplasmic reticulum membrane YJR110W 7.544077 INESSENTIAL Gene product shows sequence similarity to conserved myotubularin dual specificity phosphatase (PTP DSP) gene family (Laporte et al. (1998) Hum Mol Gen 7:1703), biological_process unknown, molecular_function unknown, YOR035C 7.430282 INESSENTIAL SHE4 Required for mother cell-specific HO expression,molecular_function unknown, YGR081C 7.368625 INESSENTIAL biological_process unknown, molecular_function unknown, YIL139C 7.276244 INESSENTIAL REV7 subunit of DNA polymerase-zeta (Pol-zeta), an enzyme whose sole function appears to be translesion synthesis, DNA repair*, zeta DNA polymerase, nucleus YOR235W 7.216005 INESSENTIAL biological_process unknown, molecular_function unknown, YPR101W 7.199219 INESSENTIAL SNT309 Component of a protein complex associated with the splicing factor Prp19p., mRNA splicing, YLR190W 7.163797 INESSENTIAL biological_process unknown, molecular_function unknown, YHR041C 7.142754 INESSENTIAL SRB2 RNA polymerase II holoenzyme mediator subunit, transcription from Pol II promoter, RNA polymerase II transcription mediator, mediator complex YDR244W 7.118227 INESSENTIAL PEX5 69-kDa protein containing tetratricopeptide repeat (TPR), protein-peroxisome targeting*, peroxisome targeting sequence binding*, cytosol* YLR320W 7.093825 INESSENTIAL biological_process unknown, molecular_function unknown, YML016C 6.931450 INESSENTIAL PPZ1 serine-threonine phosphatase Z,protein serine/threonine phosphatase, YNL071W 6.905867 INESSENTIAL LAT1 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex,dihydrolipoamide S-acetyltransferase, YBR272C 6.835469 INESSENTIAL HSM3 Hsm3p may be a member of the yeast MutS homolog family, mismatch repair, molecular_function unknown, YDR281C 6.749479 INESSENTIAL PHM6 phosphate metabolism; transcription is regulated by PHO system,molecular_function unknown, YCL007C 6.738252 INESSENTIAL CWH36 involved in cell wall biogenesis,molecular_function unknown, YDR264C 6.712965 INESSENTIAL AKR1 Ankyrin repeat-containing protein, endocytosis*, molecular_function unknown, cellular_component unknown YNL121C 6.692826 INESSENTIAL TOM70 70 kDa mitochondrial specialized import receptor of the outer membrane, mitochondrial translocation, protein transporter, mitochondrial outer membrane translocase complex YDR408C 6.526577 INESSENTIAL ADE8 glycinamide ribotide transformylase,phosphoribosylglycinamide formyltransferase, YOR141C 6.377158 INESSENTIAL ARP8 actin-related protein, biological_process unknown, molecular_function unknown, cell YJR010C-A 6.377073 INESSENTIAL SPC1 signal peptidase subunit, signal peptide processing, molecular_function unknown, signal peptidase complex YDR522C 6.315032 INESSENTIAL SPS2 involved in meiosis, meiosis, molecular_function unknown, YHL011C 6.248889 INESSENTIAL PRS3 ribose-phosphate pyrophosphokinase 3, histidine biosynthesis*, ribose-phosphate pyrophosphokinase, cytoplasm YMR138W 6.227974 INESSENTIAL CIN4 GTP-binding protein, microtubule-based process, GTP binding, microtubule YJR145C 6.196290 INESSENTIAL RPS4A Ribosomal protein S4A (YS6) (rp5) (S7A), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YCR084C 6.166231 INESSENTIAL TUP1 glucose repression regulatory protein, exhibits similarity to beta subunits of G proteins, transcription, YEL036C 6.123656 INESSENTIAL ANP1 subunit of mannosyltransferase complex, protein glycosylation, YKL016C 6.092816 INESSENTIAL ATP7 ATP synthase d subunit, ATP synthesis coupled proton transport, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATP synthase, stator stalk YPR133W-A 6.065199 INESSENTIAL TOM5 Membrane protein involved in protein translocation to the mitochondria, mitochondrial translocation, protein transporter, mitochondrial outer membrane translocase complex YBR078W 6.063203 INESSENTIAL ECM33 Homolog to sporulation specific protein SPS2 (S. cerevisiae),molecular_function unknown, YMR216C 6.047492 INESSENTIAL SKY1 Serine Protein Kinase, biological_process unknown, protein kinase, YLR349W 5.962063 INESSENTIAL biological_process unknown, molecular_function unknown, YNL165W 5.925538 INESSENTIAL biological_process unknown, molecular_function unknown, YNL051W 5.923436 INESSENTIAL biological_process unknown, molecular_function unknown, YBR003W 5.758147 INESSENTIAL COQ1 hexaprenyl pyrophosphate synthetase, ubiquinone metabolism, trans-hexaprenyltranstransferase, YOR305W 5.688902 INESSENTIAL biological_process unknown, molecular_function unknown, YDR385W 5.616965 INESSENTIAL EFT2 translation elongation factor 2 (EF-2), protein synthesis elongation, translation elongation factor, ribosome YDR271C 5.605216 INESSENTIAL biological_process unknown, molecular_function unknown, YLR370C 5.539485 INESSENTIAL ARC18 Arp2 3 Complex Subunit, actin filament organization, structural protein of cytoskeleton, Arp2/3 protein complex YBL027W 5.513131 INESSENTIAL RPL19B Ribosomal protein L19B (YL14) (L23B) (rpl5L), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YBR111C 5.507584 INESSENTIAL YSA1 Homolog to serendipity protein (D. melanogaster), biological_process unknown, molecular_function unknown, YBL039C 5.492190 INESSENTIAL URA7 CTP synthase, highly homologus to URA8 CTP synthase,CTP synthase, YLR448W 5.483372 INESSENTIAL RPL6B 60S ribosomal subunit protein L6B (L17B) (rp18) (YL16), protein biosynthesis*, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YDR174W 5.432337 INESSENTIAL HMO1 35 kDa protein belonging to the high mobility group (HMG) fanily of proteins YGR214W 5.363021 INESSENTIAL RPS0A Ribosomal protein S0A, protein biosynthesis*, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YMR004W 5.314028 INESSENTIAL MVP1 peripheral Golgi membrane protein YMR026C 5.303723 INESSENTIAL PEX12 C3HC4 zinc-binding integral peroxisomal membrane protein, peroxisome organization and biogenesis, molecular_function unknown, peroxisomal membrane YOR001W 5.199253 INESSENTIAL RRP6 involved in 5.8S rRNA processing, 35S primary transcript processing, 3'-5' exoribonuclease, nuclear exosome (RNase complex) YLR435W 5.126015 INESSENTIAL biological_process unknown, molecular_function unknown, YDL096C 5.073665 INESSENTIAL biological_process unknown, molecular_function unknown, YKL212W 5.068664 INESSENTIAL SAC1 integral membrane protein localizing to the ER and Golgi YCL058C 5.047231 INESSENTIAL FYV5 biological_process unknown, molecular_function unknown, cellular_component unknown YNL220W 4.976333 INESSENTIAL ADE12 adenylosuccinate synthetase,adenylosuccinate synthase, YIL008W 4.869762 INESSENTIAL URM1 ubiquitin like protein, protein modification, YBL101C 4.838310 INESSENTIAL ECM21 involved in cell wall biogenesis,molecular_function unknown, YPR124W 4.798780 INESSENTIAL CTR1 Copper transport protein, transport, YJR033C 4.729479 INESSENTIAL RAV1 Regulator of (H+)-ATPase in vacuolar membrane,molecular_function unknown, YBR179C 4.586783 INESSENTIAL FZO1 homolog of Drosophila melanogaster fuzzy onions gene; integral protein of the mitochondrial outer membrane which can be isolated as part of a high molecular weight complex, mitochondrion organization and biogenesis, GTPase, mitochondrial outer membrane YLR110C 4.554020 INESSENTIAL CCW12 biological_process unknown, molecular_function unknown, YPL068C 4.552017 INESSENTIAL biological_process unknown, molecular_function unknown, YML050W 4.512390 INESSENTIAL biological_process unknown, molecular_function unknown, YGR255C 4.497609 INESSENTIAL COQ6 COQ6 monooxygenase, ubiquinone metabolism, YDR116C 4.480686 INESSENTIAL biological_process unknown, molecular_function unknown, YOR290C 4.464520 INESSENTIAL SNF2 transcriptional regulator, chromatin modeling, non-specific RNA polymerase II transcription factor, nucleosome remodeling complex YNL153C 4.439555 INESSENTIAL GIM3 bovine prefoldin subunit 4 homolog (putative), protein folding, YDR378C 4.403970 INESSENTIAL LSM6 Sm-like protein,molecular_function unknown, YER110C 4.385037 INESSENTIAL KAP123 Karyopherin beta 4 YAR015W 4.317217 INESSENTIAL ADE1 phosphoribosyl amino imidazolesuccinocarbozamide synthetase,phosphoribosylaminoimidazole-succinocarboxamide synthase, YER078C 4.290512 INESSENTIAL biological_process unknown, molecular_function unknown, YEL050C 4.242412 INESSENTIAL RML2 mitochondrial ribosomal protein L2 of the large subunit, protein biosynthesis*, structural protein of ribosome, mitochondrial large ribosomal-subunit YGL084C 4.235504 INESSENTIAL GUP1 putative glycerol transporter YLR386W 4.197487 INESSENTIAL biological_process unknown, molecular_function unknown, YOR383C 4.183898 INESSENTIAL FIT3 biological_process unknown, molecular_function unknown, YGL088W 4.153030 INESSENTIAL biological_process unknown, molecular_function unknown, YNL025C 4.138303 INESSENTIAL SSN8 C-type cyclin associated with the Ssn3p cyclin-dependent kinase, repression of transcription from Pol II promoter, non-specific RNA polymerase II transcription factor*, transcription factor complex YBL072C 4.123989 INESSENTIAL RPS8A Ribosomal protein S8A (S14A) (rp19) (YS9), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YLR240W 4.119606 INESSENTIAL VPS34 phosphatidylinositol 3-kinase, protein phosphorylation*, protein kinase*, membrane fraction YGR056W 4.061059 INESSENTIAL RSC1 Member of RSC complex, chromatin modeling, molecular_function unknown, nucleosome remodeling complex YHR004C 4.035515 INESSENTIAL NEM1 Nuclear Envelope Morphology, nuclear organization and biogenesis, YMR193C-A 3.998907 INESSENTIAL biological_process unknown, molecular_function unknown, YOL143C 3.945484 INESSENTIAL RIB4 6,7-dimethyl-8-ribityllumazine synthase (DMRL synthase) YPL254W 3.924400 INESSENTIAL HFI1 transcription factor, member of Ada Gcn5 protein complex, transcription,SAGA complex YIL034C 3.918726 INESSENTIAL CAP2 beta subunit of capping protein, cell wall organization and biogenesis*, F-actin capping, actin cortical patch (sensu Saccharomyces)* YGR092W 3.863558 INESSENTIAL DBF2 Serine threonine protein kinase, cell cycle, YDR114C 3.705041 INESSENTIAL biological_process unknown, molecular_function unknown, YOR200W 3.666752 INESSENTIAL biological_process unknown, molecular_function unknown, YIL110W 3.595922 INESSENTIAL biological_process unknown, molecular_function unknown, YKR024C 3.503741 INESSENTIAL DBP7 putative RNA helicase, 35S primary transcript processing*, ATP dependent RNA helicase, nucleolus YOL009C 3.376021 INESSENTIAL MDM12 Mdm12p is a mitochondrial outer membrane protein. An Mdm12p homolog exists in S. Pombe which confers a dominant negative phenotype when expressed in S. cerevisiae, mitochondrion inheritance*, molecular_function unknown, mitochondrial outer membrane YDR392W 3.363745 INESSENTIAL SPT3 transcription factor, member of the histone acetyltransferase SAGA complex SAGA complex YDL232W 3.335393 INESSENTIAL OST4 3.6-kDa protein, probably membrane-located,dolichyl-diphosphooligosaccharide-protein glycosyltransferase, YNL309W 3.312205 INESSENTIAL STB1 Interacts with the putative transcription factor Sin3p, biological_process unknown, YDR350C 3.306679 INESSENTIAL TCM10 biological_process unknown, molecular_function unknown, YKL080W 3.303697 INESSENTIAL VMA5 vacuolar ATPase V1 domain subunit C (42 kDa), vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V1 domain YGR102C 3.287388 INESSENTIAL biological_process unknown, molecular_function unknown, YNL135C 3.283910 INESSENTIAL FPR1 peptidylprolyl cis-trans isomerase, biological_process unknown, peptidylprolyl isomerase, cytoplasm YJL159W 3.274919 INESSENTIAL HSP150 Heat shock protein, secretory glycoprotein, cell wall organization and biogenesis, cell wall structural protein, cell wall YLR357W 3.268020 INESSENTIAL RSC2 Member of RSC complex., chromatin modeling, molecular_function unknown, nucleosome remodeling complex YMR097C 3.258129 INESSENTIAL biological_process unknown, molecular_function unknown, YNL041C 3.245174 INESSENTIAL biological_process unknown, molecular_function unknown, YLR426W 3.172200 INESSENTIAL biological_process unknown, molecular_function unknown, YDR414C 3.169025 INESSENTIAL ERD1 involved in rentention of lumenal ER proteins YDR204W 3.115656 INESSENTIAL COQ4 involved in ubiquinone biosynthesis, ubiquinone metabolism, YGL236C 3.079479 INESSENTIAL MTO1 Mitochondrial Translation Optimization; Strong similarity to E. coli GidA, protein biosynthesis, molecular_function unknown, mitochondrion YPL118W 3.063795 INESSENTIAL MRP51 Component of small subunit of the mitochondrial ribosome, protein biosynthesis*, structural protein of ribosome, mitochondrial small ribosomal-subunit YNL079C 3.009212 INESSENTIAL TPM1 tropomyosin I, establishment of cell polarity (sensu Saccharomyces)*, actin lateral binding, cytokinetic ring (sensu Saccharomyces)* YGL223C 3.002647 INESSENTIAL biological_process unknown, molecular_function unknown, YCR028C 2.986199 INESSENTIAL FEN2 Amino acid permease, biological_process unknown, molecular_function unknown, YOR205C 2.985486 INESSENTIAL biological_process unknown, molecular_function unknown, YIL130W 2.958239 INESSENTIAL biological_process unknown, molecular_function unknown, YBR031W 2.917486 INESSENTIAL RPL4A Ribosomal protein L4A (L2A) (rp2) (YL2), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YMR293C 2.892441 INESSENTIAL amidase YPR135W 2.888394 INESSENTIAL CTF4 DNA polymerase alpha binding protein, DNA repair*, DNA binding, nucleus YBR044C 2.826837 INESSENTIAL TCM62 mitochondrial protein; (putative) chaperone, protein complex assembly, chaperone, mitochondrial inner membrane YPR166C 2.781199 INESSENTIAL MRP2 14 kDa mitochondrial ribosomal protein; homologous to E. coli S14 protein, protein biosynthesis, structural protein of ribosome, mitochondrial small ribosomal-subunit YMR282C 2.659334 INESSENTIAL AEP2 basic, hydrophilic 67.5 kDa protein, protein biosynthesis, molecular_function unknown, mitochondrion YER153C 2.657042 INESSENTIAL PET122 translational activator of cytochrome c oxidase subunit III, protein biosynthesis, molecular_function unknown, mitochondrial inner membrane YJL120W 2.623422 INESSENTIAL biological_process unknown, molecular_function unknown, YGR252W 2.578030 INESSENTIAL GCN5 histone acetyltransferase,histone acetyltransferase, SAGA complex YNR020C 2.577944 INESSENTIAL biological_process unknown, molecular_function unknown, YLR418C 2.541668 INESSENTIAL CDC73 RNA polymerase II accessory protein, transcription, YIL122W 2.519776 INESSENTIAL biological_process unknown, molecular_function unknown, YIL103W 2.412878 INESSENTIAL biological_process unknown, molecular_function unknown, YJR032W 2.396432 INESSENTIAL CPR7 peptidyl-prolyl cis trans isomerase, biological_process unknown, peptidylprolyl isomerase, cytoplasm YOL039W 2.380871 INESSENTIAL RPP2A 60S acidic ribosomal protein P2A (L44) (A2) (YP2alpha), protein biosynthesis*, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YGR110W 2.346137 INESSENTIAL biological_process unknown, molecular_function unknown, YPL101W 2.313896 INESSENTIAL biological_process unknown, molecular_function unknown, YOL044W 2.293468 INESSENTIAL PEX15 44 kDa phosphorylated integral peroxisomal membrane protein, protein-peroxisome targeting*, molecular_function unknown, peroxisomal membrane YLR371W 2.235388 INESSENTIAL ROM2 GDP-GTP Exchange Protein (GEP) for Rho1p, establishment of cell polarity (sensu Saccharomyces)*, signal transducer*, bud tip YJL115W 2.232823 INESSENTIAL ASF1 involved in silencing, transcription, YML026C 2.224587 INESSENTIAL RPS18B Ribosomal protein S18B, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YDL088C 2.203746 INESSENTIAL ASM4 Nuclear pore complex protein, mRNA-nucleus export*, structural protein, nuclear pore YPR120C 2.197418 INESSENTIAL CLB5 B-type cyclin, G1/S transition of mitotic cell cycle*, cyclin, cellular_component unknown YIR005W 2.161876 INESSENTIAL IST3 biological_process unknown, molecular_function unknown, cellular_component unknown YGR034W 2.114656 INESSENTIAL RPL26B Ribosomal protein L26B (L33B) (YL33), protein biosynthesis, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YCR002C 2.112760 INESSENTIAL CDC10 conserved potential GTP-ginding protein, establishment of cell polarity (sensu Saccharomyces)*, structural protein of cytoskeleton, septin ring (sensu Saccharomyces) YPL148C 2.103154 INESSENTIAL PPT2 Phosphopantetheine:protein transferase (PPTase), lipid transport, YPR125W 2.089429 INESSENTIAL biological_process unknown, YOR221C 2.084896 INESSENTIAL MCT1 malonyl-CoA:ACP transferase, fatty acid metabolism, YJL023C 2.069406 INESSENTIAL PET130 Nuclear gene encoding mitochondrial protein, biological_process unknown, molecular_function unknown, cellular_component unknown YGR188C 1.951898 INESSENTIAL BUB1 Serine threonine protein kinase required for cell cycle arrest in response to loss of microtubule function, mitotic spindle checkpoint, protein kinase, nucleus YDR463W 1.933516 INESSENTIAL STP1 Nuclear-localized protein containing zinc finger motifs, tRNA splicing, YNL167C 1.928864 INESSENTIAL SKO1 CREB like repressor, bZIP protein that binds to CRE motifs, interacts with Mig1p, transcription, YLR399C 1.869290 INESSENTIAL BDF1 Bdf1p contains two bromodomains, localizes to the nucleus and to chomosomes in spread meiotic nuclei but is excluded from the nucleolus, sporulation (sensu Saccharomyces), transcription factor, nucleus YCL016C 1.844950 INESSENTIAL biological_process unknown, molecular_function unknown, YOR036W 1.819691 INESSENTIAL PEP12 integral membrane protein; c-terminal TMD; located in endosome, Golgi to vacuole transport, t-SNARE, Golgi apparatus* YGR135W 1.756569 INESSENTIAL PRE9 proteasome component Y13, ubiquitin-dependent protein degradation, multicatalytic endopeptidase, 20S core proteasome YHL031C 1.598423 INESSENTIAL GOS1 Golgi SNARE protein, non-selective vesicle fusion*, v-SNARE, inter-Golgi transport vesicle YJR144W 1.586016 INESSENTIAL MGM101 (putative) nucleic acid interactor, mitochondrial genome maintenance, YDR231C 1.553127 INESSENTIAL COX20 protein required for maturation and assembly of cytochrome oxidase subunit II, respiration, YOR153W 1.549610 INESSENTIAL PDR5 multidrug resistance transporter,transporter, YGL078C 1.516168 INESSENTIAL DBP3 ATP-dependent RNA helicase CA3 of the DEAD DEAH box family, 35S primary transcript processing*, ATP dependent RNA helicase, nucleolus YDL041W 1.484037 INESSENTIAL KRE26 biological_process unknown, molecular_function unknown, YER061C 1.479289 INESSENTIAL CEM1 Protein homologous to beta-keto-acyl synthase, hexadecanal biosynthesis, 3-oxoacyl-[acyl-carrier protein] synthase, mitochondrion YHR013C 1.472061 INESSENTIAL ARD1 subunit of the major N alpha-acetyltransferase; complexes with Nat1p, protein acetylation, peptide alpha-N-acetyltransferase, YER016W 1.463089 INESSENTIAL BIM1 microtubule-binding protein, microtubule nucleation*, structural protein of cytoskeleton, spindle pole body* YNL096C 1.446050 INESSENTIAL RPS7B Ribosomal protein S7B (rp30), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YGL003C 1.445572 INESSENTIAL CDH1 protein required for Clb2 and Ase1 degradation, ubiquitin-dependent protein degradation*, enzyme activator, anaphase-promoting complex YPL079W 1.438917 INESSENTIAL RPL21B Ribosomal protein L21B, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YLR053C 1.436998 INESSENTIAL biological_process unknown, molecular_function unknown, YDR150W 1.401532 INESSENTIAL NUM1 Protein with variable number of tandem repeats of a 64 amino-acid polypeptide, potential Ca2+-binding site, and pleckstrin homology domain,molecular_function unknown, YCR081W 1.398836 INESSENTIAL SRB8 RNA polymerase II mediator subunit, repression of transcription from Pol II promoter, RNA polymerase II transcription mediator, transcription factor complex YOL072W 1.354866 INESSENTIAL THP1 THO2 - HPR1 Phenotype, biological_process unknown, molecular_function unknown, YLR047C 1.334995 INESSENTIAL biological_process unknown, molecular_function unknown, YLR111W 1.261492 INESSENTIAL biological_process unknown, molecular_function unknown, YGL104C 1.235540 INESSENTIAL biological_process unknown, molecular_function unknown, YIL036W 1.101811 INESSENTIAL CST6 omosome STability, DNA metabolism, molecular_function unknown, cellular_component unknown YPR164W 1.097529 INESSENTIAL KIM3 killed in mutagen, sensitive to diepoxybutane and or mitomycin C,molecular_function unknown, YPL018W 1.085152 INESSENTIAL CTF19 kinetochore protein YDL062W 1.061402 INESSENTIAL biological_process unknown, molecular_function unknown, YOR085W 1.047875 INESSENTIAL OST3 34-kDa, gamma subunit of oligosaccharyl transferase glycoprotein complex, protein glycosylation, dolichyl-diphosphooligosaccharide-protein glycosyltransferase, integral membrane protein YML112W 1.036824 INESSENTIAL CTK3 CTD kinase-I gamma subunit, protein phosphorylation*, molecular_function unknown, YPR134W 1.016290 INESSENTIAL MSS18 Involved in splicing of mitochondrial COX1 transcript,molecular_function unknown, YMR123W 0.952828 INESSENTIAL PKR1 Pichia farinosa killer toxin resistance,molecular_function unknown, YBR106W 0.936750 INESSENTIAL PHO88 regulator of Pho81, involved in regulating phosphate transport, phosphate transport, YMR219W 0.928317 INESSENTIAL ESC1 involved in silencing,molecular_function unknown, YAL010C 0.896658 INESSENTIAL MDM10 Mitochondrial outer membrane protein involved in mitochondrial morphology and inheritance, mitochondrion inheritance*, molecular_function unknown, mitochondrial outer membrane YOR104W 0.881538 INESSENTIAL biological_process unknown, molecular_function unknown, YOR002W 0.877480 INESSENTIAL ALG6 glucosyltransferase, protein glycosylation, YGR006W 0.840779 INESSENTIAL PRP18 RNA splicing factor associated with U5 snRNP, mRNA splicing, YML062C 0.828445 INESSENTIAL MFT1 mitochondrial targeting protein, protein-mitochondrial targeting, molecular_function unknown, nucleus YFR032C-A 0.757642 INESSENTIAL RPL29 Ribosomal protein L29 (YL43), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YJR122W 0.727093 INESSENTIAL CAF17 component of CCR4 transcriptional complex YPL055C 0.693619 INESSENTIAL biological_process unknown, molecular_function unknown, YDR207C 0.690344 INESSENTIAL UME6 Ume6p is a C6 zinc finger URS1-binding protein., meiosis, transcription factor, YDR194C 0.649998 INESSENTIAL MSS116 Mitochondrial DEAD box RNA helicase, RNA splicing, RNA helicase, mitochondrial matrix YKL110C 0.604311 INESSENTIAL KTI12 Protein involved in resistance to K. lactis killer toxin,molecular_function unknown, YDR512C 0.598540 INESSENTIAL biological_process unknown, molecular_function unknown, YDR197W 0.573722 INESSENTIAL CBS2 cytochrome b translational activator, protein biosynthesis, molecular_function unknown, mitochondrial inner membrane YER116C 0.555719 INESSENTIAL SLX8 biological_process unknown, molecular_function unknown, YNL119W 0.460277 INESSENTIAL biological_process unknown, molecular_function unknown, YGL066W 0.456824 INESSENTIAL biological_process unknown, molecular_function unknown, YCR051W 0.443146 INESSENTIAL biological_process unknown, molecular_function unknown, YPL008W 0.428118 INESSENTIAL CHL1 kinetochore protein in the DEAH box family, mitosis, YMR125W 0.380500 INESSENTIAL STO1 transcriptional activator of glycolytic genes YGR061C 0.326088 INESSENTIAL ADE6 5'-phosphoribosylformyl glycinamidine synthetase,phosphoribosylformylglycinamidine synthase, YBR041W 0.320164 INESSENTIAL FAT1 Fatty acid transporter, lipid transport*, long-chain-fatty-acid-CoA-ligase*, plasma membrane* YDR540C 0.312233 INESSENTIAL biological_process unknown, molecular_function unknown, YKL143W 0.311285 INESSENTIAL LTV1 low temperature viability protein, stress response, molecular_function unknown, cellular_component unknown YDR181C 0.243042 INESSENTIAL SAS4 involved in silencing at telomeres, HML, and HMR,molecular_function unknown, YLR369W 0.198271 INESSENTIAL SSQ1 mitochondrial hsp70-type molecular chaperone, DNA dependent DNA replication*, chaperone, mitochondrial matrix YGR150C 0.170626 INESSENTIAL biological_process unknown, molecular_function unknown, YPL080C 0.169200 INESSENTIAL biological_process unknown, molecular_function unknown, YOL096C 0.146665 INESSENTIAL COQ3 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase, ubiquinone metabolism, hexaprenyldihydroxybenzoate methyltransferase, YLR055C 0.125054 INESSENTIAL SPT8 transcription factor, probable member of histone acetyltransferase SAGA complex SAGA complex YIL052C 0.092873 INESSENTIAL RPL34B Ribosomal protein L34B, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YPL208W 0.085626 INESSENTIAL biological_process unknown, molecular_function unknown, YLR373C 0.083987 INESSENTIAL VID22 vacuole import and degradation,molecular_function unknown, YHR134W 0.018779 INESSENTIAL WSS1 Weak suppressor of smt3 mutant, biological_process unknown, molecular_function unknown, YOR089C -0.027969 INESSENTIAL VPS21 small GTP-binding protein; geranylgeranylated; geranylgeranylation required for membrane association; also involved in endocytosis post vesicle internalization, endocytosis, YDL194W -0.099046 INESSENTIAL SNF3 glucose sensor, transport, glucose permease, YGL136C -0.117725 INESSENTIAL biological_process unknown, molecular_function unknown, YGR027C -0.118832 INESSENTIAL RPS25A Ribosomal protein S25A (S31A) (rp45) (YS23), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YBL045C -0.140485 INESSENTIAL COR1 44 kDa core protein of yeast coenzyme QH2 cytochrome c reductase,ubiquinol-cytochrome-c reductase, YOR332W -0.150793 INESSENTIAL VMA4 vacuolar ATPase V1 domain subunit E (27 kDa), vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V1 domain YBR028C -0.187888 INESSENTIAL Probable ser thr-specific protein kinase, homolog to YKR2 and YPK1 (S. cerevisiae), biological_process unknown, molecular_function unknown, YPR087W -0.200960 INESSENTIAL biological_process unknown, molecular_function unknown, YGL213C -0.214407 INESSENTIAL SKI8 antiviral protein, mRNA is induced early in meiosis, mRNA catabolism, YMR194W -0.230779 INESSENTIAL RPL36A Ribosomal protein L36A (L39) (YL39), protein biosynthesis, structural protein of ribosome*, cytosolic large ribosomal (60S)-subunit YPL241C -0.260468 INESSENTIAL CIN2 involved in microtubule function, microtubule-based process, molecular_function unknown, microtubule YGL234W -0.296272 INESSENTIAL ADE5 glycinamide ribotide synthetase and aminoimidazole ribotide synthetase,phosphoribosylformylglycinamidine cyclo-ligase, YLR406C -0.302749 INESSENTIAL RPL31B Ribosomal protein L31B (L34B) (YL28), protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YDR393W -0.414455 INESSENTIAL SHE9 similar to Arabidopsis Cip1, lethal when overexpressed, biological_process unknown, molecular_function unknown, YOR339C -0.439812 INESSENTIAL UBC11 homolog of ubiquitin carrier protein E2-C, polyubiquitylation*, ubiquitin conjugating enzyme, cellular_component unknown YML054C -0.463484 INESSENTIAL CYB2 Cytochrome b2 [L--lactate cytochrome-c oxidoreductase],L-lactate dehydrogenase (cytochrome), YLR412W -0.468589 INESSENTIAL biological_process unknown, molecular_function unknown, YOR198C -0.494506 INESSENTIAL BFR1 involved in secretion, cytokinesis*, molecular_function unknown, cellular_component unknown YLR201C -0.539751 INESSENTIAL biological_process unknown, molecular_function unknown, YLR287C-A -0.551809 INESSENTIAL RPS30A Ribosomal protein S30A, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YPL059W -0.555801 INESSENTIAL GRX5 Protein with glutaredoxin activity, osmotic response*, glutaredoxin, cellular_component unknown YNL091W -0.595462 INESSENTIAL biological_process unknown, molecular_function unknown, YAL009W -0.603441 INESSENTIAL SPO7 sporulation protein, meiosis, molecular_function unknown, YIL153W -0.626255 INESSENTIAL RRD1 Resistant to Rapamycin Deletion, osmotic response, protein phosphatase type 2A regulator, cellular_component unknown YOR183W -0.632125 INESSENTIAL FYV12 biological_process unknown, molecular_function unknown, cellular_component unknown YDL082W -0.690871 INESSENTIAL RPL13A Ribosomal protein L13A, protein biosynthesis, structural protein of ribosome, cytosolic large ribosomal (60S)-subunit YCR031C -0.736409 INESSENTIAL RPS14A Ribosomal protein S14A (rp59A), protein biosynthesis*, structural protein of ribosome*, cytosolic small ribosomal (40S)-subunit YHR026W -0.749991 INESSENTIAL PPA1 vacuolar ATPase V0 domain subunit c'', vacuolar acidification, hydrogen-transporting two-sector ATPase, hydrogen-transporting ATPase V0 domain YMR083W -0.758286 INESSENTIAL ADH3 alcohol dehydrogenase isoenzyme III,acylglycerone-phosphate reductase, YEL046C -0.884466 INESSENTIAL GLY1 Threonine Aldolase,threonine aldolase, YML034W -0.911788 INESSENTIAL SRC1 Spliced mRNA and Cell cycle regulated gene, biological_process unknown, molecular_function unknown, YML014W -0.978494 INESSENTIAL biological_process unknown, molecular_function unknown, YDL048C -0.983087 INESSENTIAL STP4 involved in tRNA splicing, tRNA splicing, molecular_function unknown, YDR126W -0.984627 INESSENTIAL PSL10 biological_process unknown, molecular_function unknown, YBL007C -0.998021 INESSENTIAL SLA1 contains 3 SH3 domains, interacts with Bee1p, cell wall organization and biogenesis*, cytoskeletal protein binding protein, actin cortical patch (sensu Saccharomyces) YNL226W -1.013986 INESSENTIAL biological_process unknown, molecular_function unknown, YLR384C -1.026977 INESSENTIAL IKI3 required for killer toxin sensitivity,molecular_function unknown, YDR202C -1.038976 INESSENTIAL RAV2 Regulator of (H+)-ATPase in Vacuolar membrane,molecular_function unknown, YAL020C -1.064575 INESSENTIAL ATS1 similarity to human RCC1 protein, microtubule-based process, molecular_function unknown, cell YNL227C -1.095177 INESSENTIAL biological_process unknown, molecular_function unknown, YML081W -1.096717 INESSENTIAL biological_process unknown, molecular_function unknown, YPL102C -1.099819 INESSENTIAL KRE24 biological_process unknown, molecular_function unknown, YER131W -1.122346 INESSENTIAL RPS26B Ribosomal protein S26B, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YHR111W -1.124804 INESSENTIAL moeB, thiF, UBA1, biological_process unknown, molecular_function unknown, YLR056W -1.181055 INESSENTIAL ERG3 C-5 sterol desaturase, ergosterol biosynthesis, C-5 sterol desaturase, endoplasmic reticulum YDR203W -1.227827 INESSENTIAL biological_process unknown, molecular_function unknown, YHR189W -1.287608 INESSENTIAL YBL079W -1.332341 INESSENTIAL NUP170 Nucleoporin highly similar to Nup157p and to mammalian Nup155p (nup170 mutant can be complemented with NUP155), mRNA-nucleus export*, structural protein, nuclear pore YLL043W -1.347052 INESSENTIAL FPS1 glycerol channel protein, transport*, transporter, integral plasma membrane protein YKL056C -1.391198 INESSENTIAL biological_process unknown, molecular_function unknown, YDL067C -1.525566 INESSENTIAL COX9 Subunit VIIa of cytochrome c oxidase,cytochrome-c oxidase, YLR216C -1.542750 INESSENTIAL CPR6 cyclophilin related to the mammalian CyP-40, protein folding, peptidylprolyl isomerase, cytoplasm YOR182C -1.553969 INESSENTIAL RPS30B Ribosomal protein S30B, protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YER141W -1.560569 INESSENTIAL COX15 cytochrome oxidase assembly factor, cytochrome c oxidase biogenesis, molecular_function unknown, mitochondrial inner membrane YJR060W -1.603159 INESSENTIAL CBF1 basic helix-loop-helix protein, mitosis, YDR004W -1.701712 INESSENTIAL RAD57 RecA homolog (similar to DMC1, RAD51, and RAD55), interacts with Rad 55p by two-hybrid analysis YNR005C -1.965549 INESSENTIAL biological_process unknown, molecular_function unknown, YDR074W -2.117216 INESSENTIAL TPS2 Trehalose-6-phosphate phosphatase, stress response*, trehalose phosphatase, alpha,alpha-trehalose-phosphate synthase (UDP-forming) YMR179W -2.149709 INESSENTIAL SPT21 non-specific DNA binding protein, transcription, YMR257C -2.167125 INESSENTIAL PET111 translational activator of cytochrome c oxidase subunit II, protein biosynthesis, molecular_function unknown, mitochondrial inner membrane YOR167C -2.364403 INESSENTIAL RPS28A Ribosomal protein S28A (S33A) (YS27), protein biosynthesis, structural protein of ribosome, cytosolic small ribosomal (40S)-subunit YNL322C -2.464551 INESSENTIAL KRE1 putatively involved in side-chain addition to beta-1,6-glucan YJR059W -2.677117 INESSENTIAL PTK2 putative serine) threonine kinase involved in spermine metabolism, polyamine transport, YMR031C -3.011882 INESSENTIAL biological_process unknown, molecular_function unknown, YAL059W -3.012384 INESSENTIAL ECM1 putative transmembrane domain protein involved in cell wall biogenesis,molecular_function unknown,